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“The Oprah Winfrey Show” was my greatest Therapy: Oprah Winfrey

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Oprah Winfrey, Wikimedia
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Los Angeles, April 13, 2017: Talk show queen Oprah Winfrey says “The Oprah Winfrey Show” was her greatest therapy.

“I had never gone to a therapist, ever,” Winfrey told people.com.

“But I had so many therapists sitting in the chair across from me that I just sort of took it in. ‘The Oprah Winfrey Show’ was my greatest therapy.”

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Winfrey’s career as a daytime host made her a household name and helped inspire millions of people. Now, the host and actress admits she learned just as much from her guests as they did from her.

“It was the greatest teaching. It was the greatest classroom and it was my greatest therapy.

“I came out of it a better human being having listened to everybody’s stories and like, ‘I don’t want to go down that road. I saw what happened to that lady. I heard what he said.’ (IANS)

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New Combo Therapy Found Effective In Kidney Cancer Patients

With this new combination therapy, tumour shrinkage or stabilization was better than that seen in patients taking just one of the two drugs alone, the researchers found

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The study was published in journal The Lancet Oncology. Wikimedia Commons
The study was published in journal The Lancet Oncology. Wikimedia Commons

Combining an anti-angiogenesis agent, which blocks blood vessel formation, with an immunotherapy agent, has shown promising anti-tumour activity in an early phase clinical trial in patients with advanced kidney cancer who had not been previously treated, says a new study.

The findings of the study involving the combination of anti-angiogenesis agent — axitinib (trade name Inlyta) – and the immunotherapy agent — pembrolizumab (trade name Keytruda) – were published in the journal The Lancet Oncology.

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“Our results are unprecedented. The combination doubled the efficacy of the drugs when used alone and the treatment was found to be tolerable,” said Michael Atkins of Georgetown University in Washington, DC, and principal investigator for the study.

The immunotherapy agent, pembrolizumab, is an immune checkpoint inhibitor that blocks a self-defense mechanism used by cancer cells to evade attack and destruction by the body's immune cells. Wikimedia Commons
The immunotherapy agent, pembrolizumab, is an immune checkpoint inhibitor that blocks a self-defence mechanism used by cancer cells to evade attack and destruction by the body’s immune cells. Wikimedia Commons

“Specifically, over 90 percent of patients exhibited tumour shrinkage and the disease was kept under control for a median of over 20 months,” Atkins said.

The investigators started their phase-1 clinical trial of this combination in 2014 and enrolled 52 advanced renal cell carcinoma (the most common form of kidney cancer) patients who had not previously been treated for the disease.

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With this new combination therapy, tumour shrinkage or stabilization was better than that seen in patients taking just one of the two drugs alone, the researchers found.

Patients also had fewer liver abnormalities and less fatigue than those treated with other similar combination therapies, Atkins said.

“We think this combination could present a major advance in the treatment of this disease as well as help define effective combinations of similar drugs for other cancers,” Atkins said. (IANS)

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