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11-Year-Old Girl Set to Become Britain’s youngest-ever Mother, Details of pregnancy withheld: Reports

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A baby (representational image), wikimedia

London, March 18, 2017: Britain is set to have its youngest-ever mother amid reports that an 11-year-old girl is expected to give birth soon, the media reported.

The father of the baby is believed to be another minor just a few years older than the mother-to-be, the police said.

Details of the pregnancy were withheld due to legal restrictions, reported the Guardian on Friday.

The current youngest mother gave birth in 2014 when she was 12 and the father was 13, the lowest combined age of any British parents.

Their toddler, a girl, is now reportedly looked after by her 28-year-old grandmother while the teenage mother attends school.

Britain has sharply reduced its teenage birth rate over the last decade, but it remains the highest in western Europe and the sixth-highest in the EU, according to World Bank statistics, with only Romania, Bulgaria, Slovakia, Hungary and Malta with higher rates. (IANS)

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Immunotherapy Drug Pembrolizumab May Treat Rare Pregnancy Cancer, Says Research

An immunotherapy drug - Pembrolizumab- has the potential to treat a rare pregnancy cancer belonging to a group of diseases called gestational trophoblastic disease (GTD), results of a clinical trial show

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Immunotherapy Drug May Treat Rare Pregnancy Cancer. Pixabay.

London, Nov 27: An immunotherapy drug has the potential to treat a rare pregnancy cancer belonging to a group of diseases called gestational trophoblastic disease (GTD), results of a clinical trial show.

Three out of four patients with the cancerous forms of GTD went into remission after receiving the immunotherapy drug pembrolizumab in a clinical trial carried out by researchers at London’s Imperial College.

The findings, published in the journal Lancet, suggest that immunotherapy could be used as a a safer alternative to conventional treatment for the disease.

Pembrolizumab is the trial drug/ immunotherapeutic agent:

The trial, which took place at Charing Cross Hospital, is the first to show that Pembrolizumab can be used to successfully treat women with GTD, according to the study

The researchers hope that this small early stage study could provide another treatment option for women who have drug-resistant GTD and lead to a 100 per cent cure rate.

“We have been able to show for the first time that immunotherapy may be used to cure patients of cancerous GTD,” said Professor Michael Seckl, lead author of the study.

The current treatments to tackle GTD cure most cases of the disease. However, there are a small number of women whose cancers are resistant to conventional therapies and as a result have a fatal outcome,” Seckl added.

“Immunotherapy may be a life-saving treatment and can be used as an alternative to the much more toxic high dose chemotherapy that is currently used,” Seckl said.

GTD is the term used to describe abnormal cells or tumors that start in the womb from cells that normally give rise to the placenta. They are extremely rare but can happen during or after pregnancy.

Globally, 18,000 women are diagnosed annually with cancerous forms of GTD, most of whom are cured with chemotherapy or surgery.

However, up to five per cent of these women’s outcomes are fatal due to factors such as chemotherapy resistance and rare forms of the cancer such as placental site trophoblastic tumours (PSTT) that develop four or more years after the causative pregnancy has ended. (IANS)

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Breastmilk Aids to Combat Food Allergies in Newborns, says Research

Breastmilk of nursing mothers can help in protecting the newborns from developing food allergies, suggests a new research

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Breastmilk aids in combatting diseases in Newborns. Pixabay.

New York, Nov 23: Breastmilk of nursing mothers who eat foods that commonly cause allergy, such as milk, eggs, peanut, tree nuts, soy, wheat, fish and shellfish during pregnancy can help protect newborns from developing food allergies, suggests a new research.

The mouse study, led by the University of Michigan, showed that when a nursing or pregnant mother is exposed to a food protein, it combines with her antibodies, which are transferred to the offspring through breasmilk and breastfeeding.

The food protein-antibody complexes are then introduced to the offspring’s developing immune system, triggering the production of protective T immune cells that suppress allergic reactions to the food.

These protective cells also persist after antibodies from the mother are gone, promoting long-term tolerance to the food.

The findings support the recent allergy prevention guidelines, which reject prior advice urging mothers to avoid high allergic foods during pregnancy or while breastfeeding breastmilk.

“This controlled study shows that mothers should feel free to eat a healthy and diverse diet throughout pregnancy and while breastfeeding,” said James R. Baker, Professor at the University of Michigan.

“Eating a range of nutritious foods during pregnancy and breastfeeding will not promote food allergies in developing babies, and may protect them from food allergy,” Baker said.

The study, published in the Journal of Experimental Medicine, showed that breast milk from mothers who consumed allergenic foods protected against food allergy, preventing anaphylaxis as well as production of immunoglobulin E and expansion of mast cells, both hallmarks of an allergic response.

Breast milk was found protective even when fed to unrelated offspring not exposed to food allergens in utero.

In other experiments, mothers who had never consumed allergenic foods were given food-specific antibodies from other mothers. This, too, protected their breastfed offspring.

Human breast milk, fed to mice with humanised immune systems (tailored to respond to human antibodies), was also protective, suggesting that the mouse findings may translate to human infants. (IANS)

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Ryan International School Murder Mystery Solved! 16-year-old Student who wanted exams Postponed Accused of Murder

The Haryana Police had earlier claimed that Pradhuman was killed by Ryan International School bus conductor Ashok Kumar inside the toilet as the boy resisted a bid to sodomise him.

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Ryan international school
Murder mystery of the class 2 student at Ryan international school, Gurugram has finally been solved (representative image) IANS

Gurugram, November 8, 2017 : A 16-year-old student of Ryan International School in Gurugram who wanted exams and a scheduled meeting between teachers and parents delayed is the prime accused in the murder of Class 2 student Pradhuman Thakur, the CBI said on Wednesday.

CBI spokesperson Abhishek Dayal said the Class 11 student was detained on Tuesday night after “inspection of the crime spot, scrutiny of CCTV footage, call records, statements and questioning of several people” revealed that he had carried a knife inside the school campus on the day of the crime and used it to kill his junior school mate.

“The weapon used in the commission of crime is a knife which was recovered initially by police in Gurugram (Haryana). It is now with us,” Dayal told reporters here.

He said the detained student was weak in studies and “wanted to have examination and parent-teacher meeting postponed”. Pradhuman, 7, was his random target.

The parents of the detained student were kept informed throughout the investigation, said the spokesperson for the Central Bureau of Investigation.

The CBI took over the case on September 22 from Haryana Police, nearly two weeks after the Class 2 boy was found with his throat slit in a bathroom of Ryan International School.

The accused will now be produced before the Juvenile Justice Board, where the court is expected to decide whether he is to be treated as a major or a minor as per the Juvenile Justice (Care and Protection of Children) Act, 2015.

The Haryana Police had earlier claimed that Pradhuman was killed by Ryan International School bus conductor Ashok Kumar inside the toilet as the boy resisted a bid to sodomise him.

While Ashok Kumar was arrested, Pradhuman’s parents and two other staffers have claimed that he was being made a scapegoat. (ians)