Memory of a heart attack gets stored in genes through epigenetic changes: Study

A new study in London has found that the memory of a heart attack is saved in genes itself as a permanent change

2
157
The heart attack brings about activation of certain genes which stay as a permanent memory in genes. Pixabay
  • CVD includes all the diseases of the heart and circulation including coronary heart disease, angina, heart attack, congenital heart disease and stroke
  • The results of the study showed that there are many epigenetic changes in individuals who had experienced a heart attack
  • Several of these changes are in genes that are linked to cardiovascular disease

London, Sept 18, 2016: The memory of a heart attack gets stored in genes through epigenetic changes- chemical modifications of DNA that turn our genes on or off, a study has found.

Cardiovascular diseases (CVDs) which are the leading causes of death worldwide are influenced by both heredity and environmental factors.

CVD includes all the diseases of the heart and circulation including coronary heart disease, angina, heart attack, congenital heart disease and stroke.

The study examined epigenetic changes- that can lead to the development of various diseases- in people who have had a previous heart attack.

Cyanotic heart disease. Wikimedia
Cyanotic heart disease. Wikimedia

Follow NewsGram on Twitter

“During a heart attack, the body signals by activating certain genes. This mechanism protects the tissue during the acute phase of the disease and restores the body after the heart attack. It is, therefore, likely that epigenetic changes are also associated a heart attack”, said Asa Johansson, a researcher at the Uppsala University in Sweden.

The results of the study showed that there are many epigenetic changes in individuals who had experienced a heart attack.

Several of these changes are in genes that are linked to cardiovascular disease.

However, it was not possible to determine whether these differences had contributed to the development of the disease, or if they live on as a memory of gene activation associated with the heart attack, the researchers said.

“We hope that our new results should contribute to increasing the knowledge of the importance of epigenetic in the clinical picture of a heart attack, which in the long run could lead to better drugs and treatments”, Johansson added.

Follow NewsGram on Facebook

For the study, the team took blood samples from the northern Sweden population health study. Individuals with a history of a CVD were identified in the cohort. It included individuals with hypertension, myocardial infarction, stroke, thrombosis and cardiac arrhythmia.

The results were published in the journal Human Molecular Genetics. (IANS)

Click here for reuse options!
Copyright 2016 NewsGram

  • Arya Sharan

    New discoveries in the field of medical science will lead to better treatment and medicines production in future.

  • Yokeshwari Manivel

    The rate of increase in cardiovascular diseases have been a main issue of present day and getting aware of this through media is gonna be a helpful source for the public.