Tuesday, August 11, 2020
Home Life Style Health & Fitness 100-year-old Drug 'Suramin' making improvements in Language and Social interaction in Autistic...

100-year-old Drug ‘Suramin’ making improvements in Language and Social interaction in Autistic Kids

New York, 30 May, 2017: Administering a single dose of 100-year-old drug suramin — originally developed to treat African sleeping sickness — can improve symptoms of autism spectrum disorder (ASD) in children, a study said.

During the study, four boys who received the suramin infusion displayed improvement in language and social behaviour, restricted or repetitive behaviour and coping skills.

Check out NewsGram for latest international news updates.

The most changed behaviours were social communication and play, speech and language, calm and focus, repetitive behaviour and coping skills, the researchers said.

“During the time the children were on suramin, benefit from all their usual therapies and enrichment programs increased dramatically,” said lead author Robert K. Naviaux, Professor at the University of California San Diego.

Importantly, suramin caused significant improvements in language and social interaction in a 14-year-old boy who had not spoken a complete sentence in 12 years.

Follow NewsGram on Facebook

“We had four non-verbal children in the study, two 6-year-olds and two 14-year-olds. The six-year-old and the 14-year-old who received suramin said the first sentences of their lives about one week after the single suramin infusion. This did not happen in any of the children given the placebo,” Naviaux added.

The findings were reported in the Annals of Clinical and Translational Neurology.

According to Naviaux, autism is caused by metabolic dysfunction or impaired communication between cells in the brain, gut and immune system, resulting from abnormal persistence of the cell danger response (CDR) — a natural and universal cellular reaction to injury or stress.

Suramin works by inhibiting the signalling function of adenosine triphosphate (ATP) — a small molecule released from the cell as a danger signal.

NewsGram brings to you top news around the world today.

When CDR is activated, the effect of extracellular ATP is similar to a warning siren that never stops.

Suramin silences the siren, “signalling the cellular war is over, the danger has passed and cells can return to ‘peacetime’ jobs like normal neurodevelopment, growth and healing”, Naviaux noted.

However, the therapeutic benefit of suramin was temporary, as the improvements peaked and then gradually faded after several weeks as the single dose of suramin wore off, the researchers said. (IANS)

STAY CONNECTED

18,959FansLike
362FollowersFollow
1,780FollowersFollow

Most Popular

Reliving The Life Of Abanindranath Tagore

A founding artist of the Bengal school of art, Abanindranath Tagore (1871-1951) has had a profound impact on modern Indian art as we know...

Boost Immunity This Monsoon: The Tasty Way

2020 is unlike any year we have seen and in parts of the country this monsoon is unlike any we have seen. Staying healthy is...

Kohli, Rohit, Dhoni Among Most Popular Cricketers Worldwide: Study

India skipper Virat Kohli's popularity knows no bounds and once again it has been re-affirmed by a study which has revealed that the 31-year-old...

I Have Always been a Hands-on Mom: Raveena Tandon

By Puja Gupta A hands-on mom, Raveena Tandon has not just portrayed impactful and memorable characters in her career spanning over two decades but has...

Know South Africa’s Indigenous Cuisine

By Puja Gupta Food is invariably a universal connector - however, experiencing and sharing-in the food of a different land is a very personal experience. As...

PETA Moves to Delhi HC to Seek Directions to Prohibit Animal Cruelty

People for the Ethical Treatment of Animals (PETA) on Monday moved the Delhi High Court to seek directions to the central government to prohibit...

The Impact of Stress on Skin, Hair and How to Overcome It

By Puja Gupta The lockdown has resulted in stress for a lot of people - stress of being cooped inside for weeks together; the uncertainty...

People Who Play VR Games Can Develop Higher Navigational Efficiency

Adding to the growing list of studies, a new study has said that individuals playing a virtual reality (VR)-based game can develop higher navigational...

Recent Comments