Friday July 19, 2019

3 Cups of Coffee a day may Prevent you from Premature Death

Compared to Abstainers, people who drink 3-4 cups of coffee a day are more likely to see health benefits than harm, experiencing lower risks of premature death and heart disease .

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3 Cups of Coffee a day may prevent you from premature death
Someone pouring a cup of coffee. Drinking coffee could increase your health benefits, according to a new study,Thursday, Nov 23, 2017. (Photo: Diaa Bekheet)

London:

People who drink three to four cups of coffee a day are more likely to see health benefits than harm, experiencing lower risks of premature death and heart disease than those who abstain, scientists said on Wednesday.

The research, which collated evidence from more than 200 previous studies, also found coffee consumption was linked to lower risks of diabetes, liver disease, dementia and some cancers.

Three or four cups a day confer the greatest benefit, the scientists said, except for women who are pregnant or who have a higher risk of suffering fractures.

Coffee is one of the most commonly consumed drinks worldwide. To better understand its effects on health, Robin Poole, a public health specialist at Britain’s University of Southampton, led a research team in an “umbrella review” of 201 studies based on observational research and 17 studies based on clinical trials across all countries and all settings.

“Umbrella reviews” synthesize previous pooled analyses to give a clearer summary of diverse research on a particular topic.

“Coffee drinking appears safe within usual patterns of consumption,” Pool’s team concluded in their research, published in the BMJ British medical journal late on Wednesday.

Drinking coffee was consistently linked with a lower risk of death from all causes and from heart disease. The largest reduction in relative risk of premature death is seen in people consuming three cups a day, compared with non-coffee drinkers.

Drinking more than three cups a day was not linked to harm, but the beneficial effects were less pronounced.

Coffee was also associated with a lower risk of several cancers, including prostate, endometrial, skin and liver cancer, as well as type 2 diabetes, gallstones and gout, the researchers said. The greatest benefit was seen for liver conditions such as cirrhosis of the liver.

Poole’s team noted that because their review included mainly observational data, no firm conclusions could be drawn about cause and effect. But they said their findings support other recent reviews and studies of coffee intake. (VOA)

Next Story

Scientists Closing in on Blood Test to Screen People for Possible Signs of Alzheimer’s Disease

A blood test — rather than subjective estimates of thinking skills — could get the right people into studies sooner

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FILE - Dr. Jori Fleisher, neurologist, examines Thomas Doyle, 66, at the Rush University Medical Center in Chicago, July 9, 2019. VOA

Scientists are closing in on a long-sought goal — a blood test to screen people for possible signs of Alzheimer’s disease and other forms of dementia. On Monday at the Alzheimer’s Association International Conference, half a dozen research groups gave new results on various experimental tests, including one that seems 88% accurate at indicating Alzheimer’s risk.

Doctors are hoping for something to use during routine exams, where most dementia symptoms are evaluated, to gauge who needs more extensive testing. Current tools such as brain scans and spinal fluid tests are too expensive or impractical for regular check-ups.

“We need something quicker and dirtier. It doesn’t have to be perfect” to be useful for screening, said Maria Carrillo, the Alzheimer’s Association’s chief science officer.

Dr. Richard Hodes, director of the National Institute on Aging, called the new results “very promising” and said blood tests soon will be used to choose and monitor people for federally funded studies, though it will take a little longer to establish their value in routine medical care.

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“Even though no medical treatment is without risk, getting treatment for high blood pressure could be important to maintain brain health in patients with Alzheimer’s disease,” Claassen said. Pixabay 

“In the past year we’ve seen a dramatic acceleration in progress” on these tests, he said. “This has happened at a pace that is far faster than any of us would have expected.”

It can’t come too soon for patients like Tom Doyle, a 66-year-old former university professor from Chicago who has had two spinal fluid tests since developing memory problems four years ago. First he was told he didn’t have Alzheimer’s, then that he did. He ultimately was diagnosed with different problems — Lewy body dementia with Parkinson’s.

“They probably could have diagnosed me years ago accurately if they had had a blood test,” said Doyle, who represents patients on the Alzheimer’s Association’s board.

88% accuracy overall

About 50 million people worldwide have dementia, and Alzheimer’s is the most common form. There is no cure; current medicines just temporarily ease symptoms. Dozens of hoped-for treatments have failed. Doctors think studies may have enrolled people after too much brain damage had occurred and included too many people with problems other than Alzheimer’s.

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Poor sleep can predict Alzheimer’s Risk in elderly. Pixabay

A blood test — rather than subjective estimates of thinking skills — could get the right people into studies sooner. One of the experimental blood tests measures abnormal versions of the protein that forms the plaques in the brain that are the hallmark of Alzheimer’s. Last year, Japanese researchers published a study of it and on Monday they gave results from validation testing on 201 people with Alzheimer’s, other types of dementia, mild impairment or no symptoms.

The blood test results closely matched those from the top tests used now — three types of brain scans and a mental assessment exam, said Dr. Akinori Nakamura of the National Center for Geriatrics and Gerontology in Obu, Japan. The test correctly identified 92% of people who had Alzheimer’s and correctly ruled out 85% who did not have it, for an overall accuracy of 88%. Shimadzu Corp. has rights to the test and is working to commercialize it, Nakamura said.

Ruling out disorders

Another experimental test looks at neurofilament light, a protein that’s a marker of nerve damage. Abdul Hye of King’s College London gave results of a study comparing blood levels of it in 2,300 people with various neurological conditions — Alzheimer’s, other dementias, Parkinson’s, depression, multiple sclerosis, Lou Gehrig’s disease — plus healthy folks for comparison.

Levels were significantly higher in eight conditions, and only 2% of healthy folks were above a threshold they set for raising concern. The test doesn’t reveal which disorder someone has, but it may help rule one out when symptoms may be psychological or due to other problems.

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Like the Japanese test, it measures the abnormal Alzheimer protein, and the new results will show how well the test reflects what brain scans show on nearly 500 people. Pixabay

Later at the conference, Dr. Randall Bateman of Washington University School of Medicine in St. Louis will give new results on a blood test he helped develop that the university has patented and licensed to C2N Diagnostics, a company he co-founded. Like the Japanese test, it measures the abnormal Alzheimer protein, and the new results will show how well the test reflects what brain scans show on nearly 500 people.

“Everyone’s finding the same thing … the results are remarkably similar across countries, across techniques,” said Bateman, whose work is supported by the U.S. government and the Alzheimer’s Association. He estimates a screening test could be as close as three years away.

ALSO READ: Healthy Lifestyle Can Cut Risk of Developing Alzheimer Even if You Have High Genetic Risk: Study

What good will that do without a cure?

An Associated Press-NORC Center for Public Affairs Research poll last year found that most Americans would want to know if they carried a gene tied to a disease even if it was incurable. “What people want most of all is a diagnosis” if they’re having symptoms, said Jonathan Schott of University College London. “What we don’t like is not knowing what’s going on.” (VOA)