Friday April 19, 2019

A new cancer treatment developed by Indian scientists in US

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Washington: A team of Indian scientists from the prestigious Massachusetts Institute of Technology and Harvard Medical School has made an important breakthrough by developing a nano-technology which will help monitor the effectiveness of cancer therapy within hours of treatment.

“We have developed a nano-technology, which first delivers an anticancer drug specifically to the tumour, and if the tumour starts dying or regressing, it then starts lighting up the tumour in real time,” said Shiladitya Sengupta, a principal investigator at Massachusetts Institute of Technology’s (MIT) Brigham and Women’s Hospital (BWH).

“This way you can monitor whether a chemotherapy is working or not in real time, and switch the patients to the right drug early on. One doesn’t need to wait for months while taking a toxic chemotherapy only to realise later and after side effects that the drug hasn’t worked,” Mr Sengupta, a co-corresponding author of the breakthrough research published online this week in ‘The Proceedings of the National Academy of Sciences’, told news agency PTI.

The first author of the paper is Ashish Kulkarni, who comes from a small village in Maharashtra. A junior faculty at Harvard, Kulkarni trained as a Chemical Engineer at ICT Mumbai, then did a PhD in chemistry at the University of Cincinnati.

Mr Kulkarni said by using this approach, the cells light up the moment a cancer drug starts working.

“We can determine if a cancer therapy is effective within hours of treatment. Our long-term goal is to find a way to monitor outcomes very early so that we don’t give a chemotherapy drug to patients who are not responding to it,” he said.

“We’ve demonstrated that this technique can help us directly visualise and measure the responsiveness of tumours to both types of drugs,” Mr Kulkarni said.

Other members of the research team are Poornima Rao, Siva Natarajana, Aaron Goldman, Venkata S Sabbisetti, Yashika Khater, Navya Korimerla, Vineethkrishna Chandrasekara and Raghunath A Mashelkar. Except Goldman, all are Indian researchers.

“Current techniques, which rely on measurements of the size or metabolic state of the tumour, are sometimes unable to detect the effectiveness of an immunotherapeutic agent as the volume of the tumour may actually increase as immune cells begin to flood in to attack the tumour,” Mr Kulkarni said.

He said reporter nanoparticles, however, can give “us an accurate read out of whether or not cancer cells are dying”.

The technology developed by the group can be used for monitoring the effectiveness of immunotherapy, a report said.

Using a nanoparticle that delivers a drug and then fluoresces green when cancer cells begin dying, they were able to visualise whether a tumour is resistant or susceptible to a particular treatment much sooner than currently available clinical methods, said a statement from BWH.

Credits: NDTV

 

 

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Panasonic Boosts Smart Factory Business in India

Panasonic also plans to open a technical centre for its smart factory solutions which will act as a strategic base that validates smart factories with customers and be used as a training centre

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Panasonic also launches mobile computing devices in India. Flickr

Targeting Rs.1,000 crore in revenue in India from its Smart Factory solutions in the next three years, Japanese electronics major Panasonic has announced it has integrated its welding business and SMT (Surface Mount Technology) equipment business into one Smart Manufacturing Solutions company.

The smart factory solutions proposition will enable Panasonic to deliver high value-added smart solutions and services along with world-class hardware to the manufacturing industry, the company said in a statement late on Wednesday.

The company targets to achieve Rs 1,000 crore in revenue from its smart factory business in the next three years in India, with solutions and digital manufacturing expected to contribute 15 per cent to the total smart factory business revenue.

“India is adopting new-age technologies such as 5G, IoT, AI and others at a rapid pace and we will only see more investment in these technologies as we move forward,” said Hiroyuki Aota, President and CEO, Global Panasonic Smart Factory Solutions.

“To be able to cater to these growing demands, having the right and smart capabilities in manufacturing will be key, and this is what we are addressing today,” he added.

The smart factory solutions mean integrated line management system (ILNB), automated process tracker, digital reporting system and more.

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Panasonic. IANS

Panasonic’s recently introduced solution ILNB can communicate with the entire line of machinery and can automate up to 70-80 per cent of manual processes.

The digital reporting system allows real-time access to information, helping build agility and overall transparency of systems.

Also Read- Apple Accused of Fraud for Hiding Dop in iPhone Sales: Report

“The key technology to realise a Smart Factory is to connect various equipments through the Internet of Things (IoT), synchronize them and collect and control data in real time for entire production processes,” said Manish Sharma, President & CEO Panasonic India.

Panasonic also plans to open a technical centre for its smart factory solutions which will act as a strategic base that validates smart factories with customers and be used as a training centre. (IANS)