Wednesday March 20, 2019

Adults With Obstructive Sleep At Greater Risk Of Cardiovascular Diseases

Adults with moderate to severe OSA were categorised into four subtypes according to the symptoms they report: disturbed sleep, minimally symptomatic, moderately sleepy and excessively sleepy.

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The increased risk of CVD associated with OSA appears to be driven by patients in the excessively sleepy subtype, according to the researchers.
The increased risk of CVD associated with OSA appears to be driven by patients in the excessively sleepy subtype, according to the researchers. Pixabay

Adults with obstructive sleep apnoea (OSA), who experience excessive sleepiness while awake are at greater risk for cardiovascular diseases (CVD) than those who do not experience such symptoms, says a new study.

Sleep apnoea is a potentially serious sleep disorder in which breathing repeatedly stops and starts.

Adults with moderate to severe OSA were categorised into four subtypes according to the symptoms they report: disturbed sleep, minimally symptomatic, moderately sleepy and excessively sleepy.

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Sleep apnoea is a potentially serious sleep disorder in which breathing repeatedly stops and starts. Pixabay

“Multiple studies from our group have shown that patients with moderate to severe OSA throughout the world can be categorised into specific subtypes based on their reported symptoms,” said Diego R. Mazzotti, researcher at the University of Pennsylvania in the US.

“However, until now, it was unclear whether these subtypes had different clinical consequences, especially in regard to future cardiovascular risk,” said Mazzotti.

For the current study, researchers followed for nearly 12 years 1,207 adults, aged 40 or above.

Participants reported symptoms such as difficulty in falling and staying asleep, snoring, fatigue, drowsy driving and daytime sleepiness.

The findings, published in the American Journal of Respiratory and Critical Care Medicine, showed that participants exhibiting the excessively sleepy subtype were more than three times as likely to have been diagnosed with heart failure than the other three subtypes.

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They were about twice as likely to experience a heart attack, heart failure, stroke or cardiovascular death during the follow-up period than the other three subtypes. Pixabay

They were about twice as likely to experience a heart attack, heart failure, stroke or cardiovascular death during the follow-up period than the other three subtypes.

In addition, they were also more likely to experience a new or recurrent cardiovascular event during the follow-up period.

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The increased risk of CVD associated with OSA appears to be driven by patients in the excessively sleepy subtype, according to the researchers.

Studies of the cardiovascular benefits of continuous positive airway pressure, or CPAP, treatment for OSA should focus on the excessively sleepy subtype, who are likely to benefit the most from what is considered the gold standard OSA treatment, the team suggested. (IANS)

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Avoid Cheese Omelettes For a Healthier Heart

The guidelines also include weekly egg consumption as part of a healthy diet

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US, cheesemakers
At the gala event to announce the winner at the U.S. Cheese Championship, ticket-holders got to sample dozens of cheeses, including the always-popular cheddar, in Green Bay, Wis., March 7, 2019. VOA

Do you savour cheese omelettes? If so, think again as consuming more eggs and dietary cholesterol may up the risk of cardiovascular disease (CVD) and death from any cause, researchers have warned.

The study suggests that egg yolks are one of the richest sources of dietary cholesterol among all commonly consumed foods. One large egg has 186 milligrams of dietary cholesterol in the yolk.

“The take-home message is really about cholesterol, which happens to be high in eggs and specifically yolks,” said co-author Norrina Allen, Associate Professor at the Northwestern University.

“As part of a healthy diet, people need to consume lower amounts of cholesterol.People who consume less cholesterol have a lower risk of heart disease,” Allen added.

For the study, which will be published in the journal JAMA, the team involved 29,615 adults from six prospective cohort studies for up to 31 years of follow up.

They found eating 300 mg of dietary cholesterol per day was associated with 17 per cent higher risk of incident cardiovascular disease and 18 per cent higher risk of all-cause deaths.

Cheesemakers, US
Guests at the U.S. Cheese Championship gala could help themselves to samples from a giant wheel of Swiss cheese that had been among the cheeses judged in the competition, in Green Bay, Wis., March 7, 2019. VOA

The cholesterol was the driving factor independent of saturated fat consumption and other dietary fat, the team said.

Eating three to four eggs per week was associated with 6 per cent higher risk of CVD and 8 per cent higher risk of any cause of death, they added.

The researchers say that eating less than 300 milligrams of dietary cholesterol per day was the guideline recommendation before 2015. However, the most recent dietary guidelines omitted a daily limit for dietary cholesterol.

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The guidelines also include weekly egg consumption as part of a healthy diet. An adult in the US gets an average of 300 milligrams per day of cholesterol and eats about three or four eggs per week.

Other animal products such as red meat, processed meat and high-fat dairy products (butter or whipped cream) also have high cholesterol content, said lead author Wenze Zhong from the varsity. (IANS)