Saturday October 20, 2018

Alcohol addiction could be treated with diabetes medication

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By NewsGram Staff Writer

London: A new research suggested that the medication for diabetes and obesity can treat alcohol dependency.

Swedish researchers identified that interfering with the hormone GLP-1 could be a target for treating alcohol dependence.Researchers have found that a medication that resemble GLP-1, which is used to treat Type-2 diabetes as well as obesity, also could be used to treat alcohol dependence.

fb72ediabetes-photoAlcohol dependence causes morbidity as well as mortality and is a major health problem in today’s society.

“We suggest that medications that resemble GLP-1 could be used to treat alcohol dependence in humans,” said one of the researchers Elisabet Jerlhag from Sahlgrenska Academy, University of Gothenburg in Sweden.

Usually, dopamine is released in the brain’s reward center in response to drinking alcohol, which leads to a sense of euphoria.

The GLP-1-like substance prevents the ability of alcohol to increase dopamine in reward areas in the mice, suggesting that they no longer experience a reward from alcohol, the findings showed.

“The GLP-1-like substance reduced the alcohol consumption by 30-40 percent in rats that drank large quantities of alcohol for several months,” Jerlhag noted.

The researchers found that the diabetes medication also reduced the motivation to drink alcohol in rats that were bred to drink a lot of alcohol. The medication also prevented relapse drinking in rats, which is major problem for alcohol dependent individuals.

The study was published in the journal Addict Biology.

(With inputs from IANS)

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Cannabis Use Has Lasting Effects on Cognitive Skills in Teenagers Than Alcohol

Moreover, these increased with cannabis use and also were long-lasting compared to alcohol

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cannabis flower marijuana

While both alcohol and marijuana misuse are known to be associated with impairments in learning, memory, attention and decision-making, as well as with lower academic performance, a new study claimed that cannabis use has lasting effects on cognitive skills in teenagers than alcohol.

The findings, led by researchers at Universite de Montreal, showed cannabis affected cognitive functions such as perceptual reasoning, memory recall, working memory and inhibitory control.

Moreover, these increased with cannabis use and also were long-lasting compared to alcohol.

“Increases in cannabis use, but not alcohol consumption, showed additional concurrent and lagged effects on cognitive functions such as perceptual reasoning, memory recall, working memory and inhibitory control,” said Patricia Conrod, from the varsity.

“Of particular concern was the finding that cannabis use was associated with lasting effects on a measure of inhibitory control, which is a risk factor for other addictive behaviours, and might explain why early onset cannabis use is a risk factor for other addictions,” added Jean-Francois G. Morin, doctoral student at Montreal.

Cannabis
Cannabis more ‘toxic’ to teenage brains than alcohol: Study. Pixabay

“Some of these effects are even more pronounced when consumption begins earlier in adolescence,” Morin added.

For the study, published in the American Journal of Psychiatry, the team followed a sample of 3,826 Canadian high school students from 7th to 10th grade over a period of four years.

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In a context where policies and attitudes regarding substance use are being reconsidered, this research highlights the importance of protecting youth from the adverse effects of consumption through greater investment in drug-prevention programmes.

“While this study did not detect effects of teenage alcohol consumption on cognitive development, the neurotoxic effects may be observable in specific subgroups differentiated based on the level of consumption, gender or age,” Morin said. (IANS)

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