Thursday November 14, 2019

Alcohol addiction could be treated with diabetes medication

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Beer into glass on a old stone

By NewsGram Staff Writer

London: A new research suggested that the medication for diabetes and obesity can treat alcohol dependency.

Swedish researchers identified that interfering with the hormone GLP-1 could be a target for treating alcohol dependence.Researchers have found that a medication that resemble GLP-1, which is used to treat Type-2 diabetes as well as obesity, also could be used to treat alcohol dependence.

fb72ediabetes-photoAlcohol dependence causes morbidity as well as mortality and is a major health problem in today’s society.

“We suggest that medications that resemble GLP-1 could be used to treat alcohol dependence in humans,” said one of the researchers Elisabet Jerlhag from Sahlgrenska Academy, University of Gothenburg in Sweden.

Usually, dopamine is released in the brain’s reward center in response to drinking alcohol, which leads to a sense of euphoria.

The GLP-1-like substance prevents the ability of alcohol to increase dopamine in reward areas in the mice, suggesting that they no longer experience a reward from alcohol, the findings showed.

“The GLP-1-like substance reduced the alcohol consumption by 30-40 percent in rats that drank large quantities of alcohol for several months,” Jerlhag noted.

The researchers found that the diabetes medication also reduced the motivation to drink alcohol in rats that were bred to drink a lot of alcohol. The medication also prevented relapse drinking in rats, which is major problem for alcohol dependent individuals.

The study was published in the journal Addict Biology.

(With inputs from IANS)

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Successful Bariatric Surgery Among Older Adults: Study

Weight loss surgeries are proven to be successful for older adults

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Study indicates that older adults treated with bariatric surgery can recover well and have a reduced risk of obesity-related complications. Pixabay

Weight-loss or bariatric surgeries are not usually performed in people above the age of 65. But researchers, including Indian-origin, have now found that these procedures could lead to successful weight loss and better diabetes control in older adults.

The study, presented at the Society for Endocrinology annual conference in Brighton, UK, indicates that elderly patients treated with bariatric surgery (gastric bypass or gastric sleeve) can recover well and have a reduced risk of obesity-related complications, including heart disease and diabetes.

“Although based on a small number of patients, our data suggest that successful weight loss and improved diabetes control can be safely achieved with surgery in older patients, which could have real benefits for their longevity and quality of life,” said study researcher Nader Lessan from the Abu Dhabi-based Imperial College London Diabetes Centre.

Lessan and the study’s co-author Saradalekshmi Radha assessed the results of 22 patients who had attended their medical centre and who had undergone weight loss surgery after the age of 65.

Two years after weight-loss surgery, the patients had, on an average, lost 24 per cent of their original body weight.

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Data suggests that successful weight loss and improved diabetes control can be safely achieved with surgery in older adults. Pixabay

In addition, of the 11 patients who had been on insulin to control their type 2 diabetes, four no longer needed it, while for others, the total insulin dose required had significantly decreased.

The only adverse effects reported during the two year period were iron and vitamin D deficiencies, which happen in younger patients too.

Also read- Bariatric Surgery Leads To Nutritional Deficiency

“Management of obesity and diabetes in old age is challenging. There is a lot of scepticism around conducting weight-loss surgery in patients over 65,” Lessan said.

“Our study suggests these procedures could be considered in older adults as an effective intervention to aid weight loss and associated complications.” (IANS)