Wednesday April 24, 2019

Alcohol addiction could be treated with diabetes medication

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Beer into glass on a old stone

By NewsGram Staff Writer

London: A new research suggested that the medication for diabetes and obesity can treat alcohol dependency.

Swedish researchers identified that interfering with the hormone GLP-1 could be a target for treating alcohol dependence.Researchers have found that a medication that resemble GLP-1, which is used to treat Type-2 diabetes as well as obesity, also could be used to treat alcohol dependence.

fb72ediabetes-photoAlcohol dependence causes morbidity as well as mortality and is a major health problem in today’s society.

“We suggest that medications that resemble GLP-1 could be used to treat alcohol dependence in humans,” said one of the researchers Elisabet Jerlhag from Sahlgrenska Academy, University of Gothenburg in Sweden.

Usually, dopamine is released in the brain’s reward center in response to drinking alcohol, which leads to a sense of euphoria.

The GLP-1-like substance prevents the ability of alcohol to increase dopamine in reward areas in the mice, suggesting that they no longer experience a reward from alcohol, the findings showed.

“The GLP-1-like substance reduced the alcohol consumption by 30-40 percent in rats that drank large quantities of alcohol for several months,” Jerlhag noted.

The researchers found that the diabetes medication also reduced the motivation to drink alcohol in rats that were bred to drink a lot of alcohol. The medication also prevented relapse drinking in rats, which is major problem for alcohol dependent individuals.

The study was published in the journal Addict Biology.

(With inputs from IANS)

Next Story

Diabetes During Pregnancy Spikes up the Risk in Kids Later

For the study, the researchers included 73,180 mothers

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The study showed that a child or teenager whose mother had gestational diabetes -- diabetes during pregnancy -- was nearly twice as likely to develop diabetes before the age of 22 years. Pixabay

Children and youths whose mothers had diabetes during their pregnancy are themselves at an increased risk of the disorder, say researchers, including one of Indian-origin.

The study showed that a child or teenager whose mother had gestational diabetes — diabetes during pregnancy — was nearly twice as likely to develop diabetes before the age of 22 years.

The association was found in children from birth to the age of 22 years, from birth to 12 years, and from 12 to 22 years, said the study, published in Canadian Medical Association Journal.

Diabetes
Representational image. Pixabay

“Although Type-1 and Type-2 diabetes in parents are well-established risk factors for diabetes, we show that gestational diabetes mellitus may be a risk indicator for diabetes in the mother’s children before age 22,” said Kaberi Dasgupta, clinician-scientist from the McGill University in Canada.

“This link of diabetes in children and youth with gestational diabetes in the mother has the potential to stimulate clinicians, parents, and children and youth themselves to consider the possibility of diabetes if offspring of a mother with gestational diabetes mellitus develop signs and symptoms such as frequent urination, abnormal thirst, weight loss or fatigue,” said Dasgupta.

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According to World Health Organzation, diabetes can be treated and its consequences can be avoided or delayed with diet, physical activity, medication and regular screening and treatment for complications.

For the study, the researchers included 73,180 mothers. (IANS)