Saturday March 23, 2019

Amazing Fact! Your Genes Determine Your Quality of Sleep

"Our study suggests that many of the genes important for sleep in animal models may also influence sleep in humans and opens the door to better understanding of the function and regulation of sleep," Dashti added.

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genes
This was comparable to other well-recognised factors that influenced sleep duration. Pixabay

Experiencing problems like insomnia or hypersomnia could be genetic, say researchers who identified 76 new gene regions associated with the time a person sleeps.

It is well known that regularly getting adequate sleep — 7 to 8 hours per night — is important for health, and both insufficient sleep — 6 or fewer hours — and excessive sleep — 9 hours or more — have been linked to significant health problems.

Family studies have suggested that 10 to 40 per cent of variation in sleep duration may be inherited, and previous genetic studies have associated variants in two gene regions with the sleep duration.

sleep
“Our study suggests that many of the genes important for sleep in animal models may also influence sleep in humans and opens the door to better understanding of the function and regulation of sleep,” Dashti added. Pixabay

The study from the Massachusetts General Hospital (MGH) in Boston, US, analysed genetic data from more than 446,000 participants, who self-reported the amount of sleep they typically received.

The study identified 78 gene regions — including the two previously identified — as associated with sleep duration.

While carrying a single gene variant influenced the average amount of sleep by only a minute, participants carrying the largest number of duration-increasing variants reported an average of 22 more minutes of sleep, compared with those with the fewest.

This was comparable to other well-recognised factors that influenced sleep duration.

 

sleep
Family studies have suggested that 10 to 40 per cent of variation in sleep duration may be inherited, and previous genetic studies have associated variants in two gene regions with the sleep duration. Pixabay

“While we spend about a third of our life asleep, we have little knowledge of the specific genes and pathways that regulate the amount of sleep people get,” said Hassan Saeed Dashti from MGH.

“Our study suggests that many of the genes important for sleep in animal models may also influence sleep in humans and opens the door to better understanding of the function and regulation of sleep,” Dashti added.

The study, published in Nature Communications journal, also found shared genetic links between both short and long sleep duration.

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It also found factors such as higher levels of body fat, depression symptoms and fewer years of schooling, implying negative effects from both too little and too much sleep.

While short sleep duration was genetically linked with insomnia and smoking, long sleep duration was linked with ailments such as schizophrenia, Type-2 diabetes and coronary artery disease. (IANS)

Next Story

Childhood Maltreatment Strongest Risk Factor for Depression in Adulthood: Lancet

The findings are to develop or improve risk-adapted interventions for people susceptible to a worse long-term clinical outcome

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depression
Fourteen had a remission period of less than two months and could therefore be regarded as having chronic depression. Pixabay

Facing trauma in childhood can significantly change the structure of the brain, which may result in severe depression which could even be recurrent in adulthood, say researchers.

The results from MRI scan images suggest that both childhood maltreatment and recurring depression are associated with similar reductions in the surface area of the insular cortex, part of the brain that regulates emotion and self-awareness.

This reduction in the brain could make a future relapse more likely, said the study, published in The Lancet Psychiatry journal, which found childhood maltreatment one of the strongest risk factors for major depression in adulthood.

depression
Depression is among the leading causes of disability in the U.S. and is being closely monitored by health authorities amid rising suicides nationwide. Pixabay

“Given the impact of the insular cortex on brain functions such as emotional awareness, it’s possible that the changes we saw make patients less responsive to conventional treatments,” said lead researcher Nils Opel from the University of Munster in Germany.

The study included 110 patients aged 18 to 60 years. Of the 75 patients who experienced a relapse, 48 had experienced one additional episode, seven reported two episodes, and six experienced three episodes.

Fourteen had a remission period of less than two months and could therefore be regarded as having chronic depression.

depression
This reduction in the brain could make a future relapse more likely, said the study, published in The Lancet Psychiatry journal. Pixabay

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The findings are to develop or improve risk-adapted interventions for people susceptible to a worse long-term clinical outcome.

Future psychiatric research should therefore explore how the findings could be translated into special attention, care and treatment that could improve patient outcomes, the study noted. (IANS)