Tuesday December 18, 2018

Anti-stress hormone linked to breast cancer risk

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London: Women with low levels of an anti-stress hormone have an increased risk of getting breast cancer, says a new study.

The study focused on a hormone which circulates freely in the blood, enkephalin, with pain- and anxiety-reducing properties. Enkephalin also reinforces the immune system by directly affecting immune cells. Credits: https://www.google.co.in/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=0CAYQjB1qFQoTCPiMsv7f3MYCFcUrpgodVqIA4Q&url=http%3A%2F%2Fwww.choctawnation.com%2Fnews-room%2Fpress-room%2Fmedia-releases%2Fchoctaw-bike-team-encourages-breast-cancer-awareness%2F&ei=CB6mVfjoO8XXmAXWxIKIDg&bvm=bv.97653015,d.eXY&psig=AFQjCNEi8zFFmDRriJ0iC8kBpejk9sc6Iw&ust=1437035987055497

“Among women with the lowest levels of the hormone, the risk of breast cancer was more than three times that of the women with the highest levels of the hormone. This is one of the strongest correlations between cancer risk and a freely circulating biomarker ever described,” said Olle Melander, professor at Lund University, Sweden.

The study that appeared in the Journal of Clinical Oncology, was based on blood samples taken from over 1,900 women. The average age of the women studied was 57. The women were followed up with regard to breast cancer for an average period of 15 years.

The researchers said geographical location and age, in spite of the adjustments in the study, may be significant. After further studies, the results will facilitate prevention and early detection of breast cancer.

For those with an increased risk of breast cancer, potential preventive treatments could take the form of lifestyle interventions to reduce stress and new drugs.

“Our immediate plan is to investigate how to affect the level of enkephalin in healthy individuals. We will do this primarily in a study with a smaller number of women. We are also interested in the hormone’s role in other cancers,” said co-author Mattias Belting and professor at Lund University, Sweden.

( IANS)

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Here’s How Exercise Can Help Breast Cancer Survivors

Among those who completed the program, those who received the lifestyle intervention were about 50 per cent more likely to have disease-free survival than those who received the general recommendations

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How exercise can help breast cancer survivors. Pixabay

Survivors of early-stage breast cancer who exercise and eat a healthy diet are more likely to lose weight and experience higher rates of disease-free survival, a new study suggests.

The research is based on an examination of a lifestyle intervention that included exercise, diet, and at least one other component such as counselling, stress management, and discontinuing tobacco smoking.

The study showed that obesity and low physical activity are associated with higher risks of developing breast cancer, as well as an increased risk of recurrence and reduced survival.

“Lifestyle intervention might improve the prognosis of breast cancer patients if adherence is high,” said Wolfgang Janni from the University of Ulm in Germany.

“Many breast cancer survivors would like to contribute actively to improving their prognosis, and guiding them on lifestyle factors that can help them control weight is one possible way to positively impact patient outcomes,” said Janni.

For the study, the researchers enrolled 2,292 women among which all had a body mass index of 24 or higher.

Cancer
Cancer Ribbon. Pixabay

Some women were randomly assigned to receive either telephone-based lifestyle intervention for two years while others received general recommendations for a healthy lifestyle alone.

Those who received the telephone calls were given advice on how to improve their diets, lower fat intake, increase physical activity, achieve moderate weight loss and other tips that were geared to their specific needs.

Findings, presented at the 2018 San Antonio Breast Cancer Symposium in the US, demonstrated that patients in the lifestyle intervention arm had lost an average of one kg, while the patients in the control group had gained an average of 0.95 kg.

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Overall, 1,477 patients completed the lifestyle intervention. Those who completed the program had a 35 per cent higher rate of disease-free survival than those who began the program but did not complete it.

Among those who completed the program, those who received the lifestyle intervention were about 50 per cent more likely to have disease-free survival than those who received the general recommendations. (IANS)