Wednesday December 19, 2018

Antibiotics after appendicitis surgery prolong hospital stay

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New York: Antibiotic use following surgery for complicated appendicitis may do more harm than good, suggests new research.

The researchers found that patients who received antibiotics following complicated appendicitis surgery remained in the hospital up to one day longer than similar patients who had not received antibiotics.

“Our study indicates antibiotics may not be necessary following surgery for complicated appendicitis,” said lead researcher Dennis Kim from Los Angeles Biomedical Research Institute in the US.

The researchers studied the outcomes over five years for 410 adults with complicated appendectomies, or those where the appendix was found to be perforated or gangrenous.

Post-operative antibiotics were administered to 274 of those patients, or 66.8 percent.

The study compared patients who received post-operative antibiotics to those who had not received the medications and found no significant difference in wound complications among the two groups.

The 274 patients who received post-operative antibiotics did have slightly longer hospital stays – an average of about one day longer – than the patients who did not receive the medication.

“Antibiotics are not without risks, costs or complications. While further study is needed, surgeons and physicians may wish to re-examine or be more selective in deciding which patients may potentially benefit from post-operative antibiotic therapy for complicated appendicitis,” Kim noted.

The study was published online in the American Journal of Surgery.

(IANS)

 

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Feeding Probiotics to Infants Daily May Reduce Antibiotic Prescription in Future

For the study, the team pooled data from twelve studies together. The probiotics used in the reviewed studies were strains of Lactobacillus and Bifidobacterium

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Feeding probiotics to infants and children daily may significantly stave off the need for antibiotic treatment, a finding that may help address the global rise in drug-resistant infections, said researchers.

The study found that infants and children were 29 per cent less likely to have been prescribed antibiotics if they received probiotics as a daily health supplement.

The results, published in the European Journal of Public Health, are very intriguing, the researchers said.

“Given this finding, potentially one way to reduce the use of antibiotics is to use probiotics on a regular basis,” said Daniel Merenstein, professor at Georgetown University.

According to the World Health Organization (WHO), antibiotic resistance occurred among 500,000 people with suspected bacterial infections across 22 countries.

Reducing the use of antibiotics is one strategy in combating resistance.

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Say no to your kids for junk food, instead add healthy snacks. Pixabay

“We already have evidence that consuming probiotics reduces the incidence, duration, and severity of certain types of common acute respiratory and gastrointestinal infections,” Merenstein said.

However, it is not clear how probiotics help fight infections.

Merenstein said: “There are many potential mechanisms, such as probiotic production of pathogen inhibitors, immune regulation, among others.

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“We don’t know all the mechanisms probiotic strains may leverage. But since most of the human immune system is found in the gastrointestinal tract, ingesting healthy bacteria may competitively exclude bacterial pathogens linked to gut infections and may prime the immune system to fight others,” he explained.

For the study, the team pooled data from twelve studies together. The probiotics used in the reviewed studies were strains of Lactobacillus and Bifidobacterium. (IANS)