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Birth of a Baby conceived through a “three person” Fertility Technique wipes out trauma of Zika

In November, the WHO declared that Zika was no longer a global emergency, but it did not change the global risk assessment even in December

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FILE - A worker of the Ministry of Public Health and Population fumigates in the street against mosquito breeding to prevent diseases such as malaria, dengue and Zika in Port-au-Prince, Haiti, Feb. 15, 2016. VOA
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New Delhi, December 22, 2016: The rapid rise of the Zika infections across many parts of the world had a large section of the population mightily worried till its “global emergency” tag was removed, but there was much cheer at the birth of a baby conceived through a “three person” fertility technique.

The outbreak of the mosquito-borne virus ultimately led to the terrifying discovery that Zika infection during pregnancy causes microcephaly in their babies — that results in unusual smallness of their heads — and other severe fetal brain defects.

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In November, the WHO declared that Zika was no longer a global emergency, but it did not change the global risk assessment even in December. Like most mosquito-borne diseases Zika too is a seasonal disease that could repeatedly return.

A vaccine for Zika therefore seemed to catch the imaginations of medical researchers across the world with several papers reporting positive results for experimental vaccines in animal models and raising hope of an effective vaccine for humans in the near future. In August, the National Institute of Allergy and Infectious Diseases (NIAID), part of the US National Institute of Health, even announced the launch of a clinical trial of a vaccine candidate intended to prevent Zika virus infection.

In terms of vaccine development, the US Food and Drug Administration (FDA) approving the first clinical trial to test a lung cancer vaccine developed in Cuba could prove to be a watershed moment in fighting the deadly disease which can result from lifestyle factors such as smoking.

A big boost in the fight against cancer, however, came from Chinese scientists who used for the first time the revolutionary gene editing technique CRISPR-Cas9 to treat a patient with aggressive lung cancer as part of a clinical trial.

While the results of the trial are yet to be disclosed, a US advisory panel also approved the human use of CRISPR, for a study designed to target three types of cancer.

The experiment, proposed by researchers at the University of Pennsylvania, would use CRISPR-Cas9 technology to modify patients’ own T-cells to make them more effective in attacking melanoma, multiple myeloma and sarcoma.

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If the technology is found to be safe for human use, it could open up pathbreaking new approach to treating several deadly diseases, not just cancer.

In a major step towards understanding what happens when pregancies go wrong, for example, during miscarriage, as well as towards improving IVF rates, a team of researchers led by the University of Cambridge succeeded this year to keep human embryos alive in a petri dish for an unprecedented 13 days. Until now scientists were unable to keep embryos alive beyond seven days.

The technique shed new light on how embryos develop and researchers believe that it could open up new avenues of research aimed at helping improve the chances of success of IVF.

In yet another good news for parents who cannot conceive naturally, a baby boy was born earlier this year in Mexico through the use of a new “three person” fertility technique, called the “spindle nuclear transfer,” for the first time.

The boy, born to a Jordanian couple, has the usual DNA from his parents, and a small amount of genetic code from a donor. The use of this reproductive technology was intended to prevent the newborn inheriting Leigh syndrome, a genetic disorder. The parents were being treated by a US-based team but the delivery was carried out in Mexico because of absence of laws preventing it.

Later this year, Britain’s fertility regulators approved the use of the three parent technique that uses DNA from three progenitors (two women, one man) to prevent children being born with deadly genetic illnesses.

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This is also the year that made us aware that emerging technologies such as artificial intelligence and virtual reality can have greater use in medical science — from predicting risk for Alzheimer’s disease to providing effective stimuli to increase movement speeds in people with Parkinson’s Disease.

The launch and increased use of numerous healthcare apps, wearable devices to track your heart rate or how well you slept the previous night, and so on, along with the rise in use of other digital technologies to offer diagnosis and care helped the year take a giant stride towards achieving what we have yearned for years — reducing dependence on others for management of our own healthcare.

After all, what else is technology for if not giving you more control over your own life? (IANS)

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Ebola Not A Global Health Emergency: WHO

WHO advised DRC's nine neighboring countries that they were at high risk of having the disease spread into their territories

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An emergency committee convened by the World Health Organization has decided that the Ebola outbreak in eastern Democratic Republic of the Congo does not constitute a public health emergency of international concern.

The WHO said Wednesday that 216 cases of Ebola and 139 deaths had been reported, and its International Health Regulations Emergency Committee said the outbreak was a matter of serious concern, especially since it is occurring in an area of conflict in eastern DRC. It said this posed problems for health workers who need to move around freely and track people who are infected with the virus and need treatment.

But the committee said that one reason it did not regard the outbreak as a global threat was that the virus had not spread into neighboring countries.

Congo,ebola
A Congolese health worker administers Ebola vaccine to a boy who had contact with an Ebola sufferer in the village of Mangina in North Kivu province of the Democratic Republic of the Congo. VOA

Committee Chairman Robert Steffan said the international response to the outbreak had been very good. He said WHO and other agencies had achieved quite a lot since the outbreak was declared Aug. 1. In fact, he said the disease was being brought under control in North Kivu province.

The disease is flaring up in another province, and the response is being concentrated in this area, he said, “so we do have some optimism that this outbreak, just like the one in May, will be brought under control within reasonable time.”

Steffan said the committee agreed that declaring an international emergency at this time would hinder efforts to contain the Ebola virus. He said a declaration would have implications for travel and trade, making it difficult for needed experts and supplies to access the affected areas.

Ebola, WHO
A health care worker from the World Health Organization, left, gives an Ebola vaccination to a front line aid worker who will then vaccinate people who might potentially have the virus, in Mbandaka, Congo. VOA

However, as a precaution, WHO recommended exit screenings, including at airports, ports and land crossings. But it noted that entry screenings, particularly in distant airports, would have no public health benefit and would be costly.

Also Read: North Kivu And Ituri, Congo To Welcome More Than 80,000 Children In This New School Year

WHO advised DRC’s nine neighboring countries that they were at high risk of having the disease spread into their territories, and it said it was supporting them with equipment and personnel. It said these preparedness activities were expensive and would require substantial financial support from the international community. (VOA)