Thursday March 21, 2019

Blocking a gene may prevent heart diseases: Study

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picture from- www.bioethics.com

Toronto: Blocking the expression of a gene may help prevent illnesses linked to excessive fat in blood such as cardiovascular and pancreatic diseases, says a new study. dna-163466_640

The researchers found that shutting down the expression of this gene decreases in blood the concentration of triglycerides – lipids that come from fats carried by our food or produced by our bodies – even in various severe forms of hypertriglyceridemia.

Higher levels of triglycerides in blood or hypertriglyceridemia is often associated with frequent health issues, such as obesity or diabetes.

The gene in question codes for the apoC-III protein.

“Our study suggests that the protein apoC-III plays a key role in the management of triglycerides. Triglycerides, like cholesterol, are lipids,” said first author of the study Daniel Gaudet from University of Montreal in Canada.

“Depending on the cause, the accumulation of triglycerides in blood is associated with an increased risk of cardiovascular and pancreatic illnesses, and other complications,” Gaudet noted.

“Our conclusions are promising in terms of the prevention of the risk associated with the accumulation of fat in blood,” he pointed out.

The research was published in the New England Journal of Medicine.

(IANS)

Next Story

Heart Strokes No More Disease of Just Elders, Now As Likely Among Young Adults

While the traditional risk factors include diabetes, high blood pressure, smoking, family history of premature heart attack and high cholesterol, substance abuse, including marijuana and cocaine were more the reason behind the increased heart attacks in younger patients.

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The study compared people aged 41-50 years and 40 or younger heart attack survivors and found that among patients who suffer a heart attack at a young age overall is 40 or younger. VOA

A heart attack, known earlier as a disease of the old, is now strikingly common in people aged 40 and below, finds a study.

The study compared people aged 41-50 years and 40 or younger heart attack survivors and found that among patients who suffer a heart attack at a young age overall is 40 or younger.

In addition, the proportion of people below 40 having a heart attack has been increasing, rising by 2 per cent each year for the last 10 years.

“It used to be incredibly rare to see anyone under age 40 come in with a heart attack and some of these people are now in their 20s and early 30s,” said Ron Blankstein, Associate Professor at Harvard University.

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Good habits like avoiding tobacco, regular exercise, heart healthy diet, weight loss if required, managing blood pressure and cholesterol, controlling diabetes if required, and staying away from substance abuse need to be maintained for a good heart. pixabay

Importantly, youngest heart attack survivors have the same likelihood of dying from another heart attack or stroke as survivors over 10 years older.

While the traditional risk factors include diabetes, high blood pressure, smoking, family history of premature heart attack and high cholesterol, substance abuse, including marijuana and cocaine were more the reason behind the increased heart attacks in younger patients.

The findings will be presented at the American College of Cardiology’s 68th Annual Scientific Session in New Orleans.

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While the traditional risk factors include diabetes, high blood pressure, smoking, family history of premature heart attack and high cholesterol, substance abuse, including marijuana and cocaine were more the reason behind the increased heart attacks in younger patients. Pixabay

For the study, the researchers included a total of 2,097 young patients.

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They found that the group below 40 had more spontaneous coronary artery dissection — a tear in the vessel wall, which tends to be more common in women, especially during pregnancy.

Good habits like avoiding tobacco, regular exercise, heart healthy diet, weight loss if required, managing blood pressure and cholesterol, controlling diabetes if required, and staying away from substance abuse need to be maintained for a good heart, Blankstein suggested. (IANS)