Cancer research has just got a huge boost. The rejuvenated shot comes with the development of an error free and accurate test by scientists that predicts the chances of being implicated with cancer up to 13 years in the future.
The breakthrough was made by researchers at Harvard and Northwestern University, by making use of the discovery of tiny but significant changes taking place in the body, more than a decade before cancer was diagnosed.
According to the research, published in the online journal Ebiomedicine, the protective caps on the ends of chromosomes, which prevent DNA damage, were more worn down for those who went on to develop cancer.
The protective caps, better known as “telomeres”, were found to be much shorter than they should have been. They continued to get shorter and then suddenly stopped shrinking four years before the cancer developed.
Dr Lifang Hou, the lead study author, told The Telegraph, “Because we saw a strong relationship in the pattern across a wide variety of cancers, with the right testing these procedures could be used eventually to diagnose a wide variety of cancers.”
“Understanding this pattern of telomere growth may mean it can be a predictive biomarker for cancer. We found cancer has hijacked the telomere shortening in order to flourish in the body”, he further said.
For every ten adults in the world, four suffer from functional gastrointestinal disorders of varying severity, say Researchers, adding that people think it’s embarrassing to talk about stomach and bowel symptoms.
Functional gastrointestinal disorders, FGIDs, is a collective term for chronic disorders in the gastrointestinal tract. The symptoms may arise throughout the gastrointestinal tract. From the upper part, the esophagus and stomach, they can include heartburn, acid reflux and indigestion (dyspepsia).For the lower parts (the intestines), chronic constipation, abdominal distension or bloating, and irritable bowel syndrome (IBS) are among the complaints.
The current study, published in the journal Gastroenterology, gives an overall picture of the global prevalence of FGIDs. Data of more than 73,000 people in 33 countries were collected by means of web-based questionnaires and face-to-face (household) interviews.
“It’s striking how similar the findings are between countries. We can see some variations but, in general, these disorders are equally common whatever the country or continent,” said study author Magnus Simren from University of Gothenburg in Sweden.Web-based questionnaires were used in most of the countries in the study.
In some countries, instead, the respondents were asked to reply to the questions when an interviewer read them aloud.The questions posed to the respondents were based on the diagnostic criteria for IBS and other FGIDs. Particulars of other diseases and symptoms, living conditions, quality of life, healthcare consumption, etc. were also requested.
The findings showed that the prevalence of FGIDs was higher in women than in men, and clearly associated with lower quality of life. According to the questionnaire responses, 49 per cent of the women and 37 per cent of the men met the diagnostic criteria for at least one FGID. The severity of the disorders varied, from mild discomfort to symptoms that adversely affected the quality of life to a high degree.
The prevalence of FGIDs was also strongly associated with high consumption of healthcare, such as visits to the doctor and use of medication, but also surgery, the study said. (IANS)
Smoking and tobacco use can have a serious impact on the fertility of both men and women, and consequently the quality of life in pregnancy. These health tips by expert can help. If a woman is a regular smoker, then it has a double effect on a woman’s fertility. Smoking can harm both the eggs and the uterus. It not only affects her egg quality, but can also have endometrial effect. Many studies too have shown that smoking can have negative effects on fertility, notes Dr Apurva Satish Amarnath, Fertility Consultant, Nova IVF Fertility.
“In women, smoking decreases in vitro fertilization (IVF) and intrauterine insemination (IUI) pregnancy rates by about half. Smoking also increases miscarriage rates. smoking also reduces the egg reserve of the woman which is not a reversible condition. For instance, if we are to compare two women with the same characteristics in terms of egg quality, quantity, BMI, AMH-level, among others, the chances are that the non-smoking woman will conceive faster than the smoking woman. If a woman quits smoking completely, then the chances of conception improve and the risk of miscarriage reduces,” Dr Apurva told IANSlife ahead of the International Anti-Tobacco Day on May 31.
From the male’s perspective, the carcinogen quality of cigarettes in general affects the motility of the sperm and excessive smoking can lead to the poor sperm count and other fertility problems. As compared to females, the condition can be reversible.
If a man completely gives up smoking the quality of his sperms can improve, resulting in his fertility improving in a span of 3-6 months after quitting completely, she said.
Smoking during pregnancy
According to Dr Sandeep Chadha, Consultant Obstetrician and Gynecologist at Motherhood Hospital, Noida, smoking during pregnancy are dangerous for both mother and the baby.
If a mother smokes, the 4,000 harmful chemicals present in each cigarette passes directly to the baby through the mother’s bloodstreams. In such cases, the risk of stillbirth and miscarriage goes up besides an increased risk of low birth weight, baby’s heart rate, breathing problem and premature delivery, Dr Sandeep told IANSlife.
These risks to the baby multiply with the number of cigarettes smoked during pregnancy. Not only for babies, but tobacco smoking is also harmful to the mother, increasing her risk of cancers, cardiovascular disease, emphysema, and other conditions.
Passive smoking and childbirth
A study has presented that exposure to secondhand smoke was associated with lower IQs in children. For babies exposed to secondhand smoke, there is an increase in risk for developing asthma attacks, breathing problems, ear infections, impaired lung development, and coughing.
Children exposed to secondhand smoke require more ear tube surgeries than those who are not exposed. Sudden infant death syndrome is more common in babies born to women who smoked during pregnancy as well as in babies exposed to secondhand smoke. Exposure to second-hand smoking by pregnant mothers is similar to first hand smoking.
More than 51 percent of women respondents say that Indian schools do not have a proper system to prepare teen and adolescent girls regarding the onset of menstrual periods. Nearly 60 percent women feel schools lack adequate facilities for girls to change and dispose of sanitary pads off, says a survey.
Today is Menstrual Hygiene Day 2020 falling , and feminine hygiene brand Everteen had conducted the fifth edition of its annual Menstrual Hygiene Survey.
The survey was conducted among nearly 7000 Indian women participating from various cities of India including Delhi, Mumbai, Bangalore, Chandigarh, Hyderabad, Ahmedabad and Kolkata.
Over 51 percent women respondents claimed that Indian schools do not have adequate systems to educate or mentally prepare teen and adolescent girls regarding the onset of menstrual periods. More than 95 percent women asserted that Indian school system should have some awareness programs to prepare girls on the subject. The survey also revealed that during adolescence, nearly 60 percent women did not have any prior knowledge about menstrual periods. In fact, as many as 38 percent women had first misinterpreted it as an injury or disease.
In terms of infrastructure, almost 59 percent women felt that schools do not have adequate cleanliness of public toilets or facilities for girls to change and dispose sanitary pads off.
Chirag Pan, CEO, PAN Healthcare, says, “Menstrual hygiene and wellness have been known issues in the Indian context. While there has been progress in recent years, it is imperative that we leverage our strength in the Indian value-based systems and inculcate the importance of good menstrual hygiene from the onset of puberty itself. Schools can and must play a pivotal role in bringing this paradigm shift through classroom education, awareness programs and focused infrastructure development.”
In workspaces too, 41 percent women felt their office needed better cleanliness and facilities to change and dispose sanitary pads off in toilets.
The survey also suggests that the role that doctors can play in preventing gynecological problems is significantly downplayed due to the shame and guilt associated with menstrual cycles in Indian context. More than 50 percent women said they have had some gynecological infection or problem such as UTI, rashes, foul smell or itching during or after menstrual cycle in the past one year. Among these, 20 percent of women had such issues more than 3 times during the year. More than 64 percent women have faced irregularities in their period dates, out of which half have had to deal with it more than 3 times in a year. Ironically, only 37 percent of women said they consult a doctor in case or irregular periods, whereas 32 percent prefer to discuss it within the family and 30 percent just ignore it. Similarly, more than 54 percent women have had white discharge, but only 25 percent prefer to consult a doctor.
As many as 56 percent women believe that menstruation is still perceived as a taboo in Indian society. Not surprisingly, then, more than 42 percent of women felt uncomfortable buying sanitary essentials from a shop or a chemist, especially when there were several other customers. Because of the guilt associated with menstrual cycle, 87 percent women admitted that they had to hide or secretly take their sanitary product for changing. Interestingly, more than three-fourth of the respondents said that menstruation would not have been such a taboo subject in the society if men had it too!
Another key revelation from the survey shows that 53 percent women have used a public toilet more than 3 times at an office, mall or cinema hall to change sanitary product. Hariom Tyagi, CEO, Wet and Dry Personal Care,says, “Our survey shows that 75 percent women feel uncomfortable having to use public toilets to change sanitary products. Yet, more than 93 percent women still use sanitary napkins. By switching to better, modern-age menstrual hygiene methods (MHM) such as menstrual cups, women can reduce the number of times they have to change their sanitary product in a day. Many women have told us that using menstrual cups has greatly reduced their daily discomfort due to periods.” The survey revealed that menstrual cups are now being used by 4 percent of the women, and their adoption has overtaken tampons by almost double.
One of the alarming trends that emerged from the survey shows that more than one-third women said they have used a pill or some other method to delay periods in case of an important occasion. (IANS)