Tuesday August 14, 2018
Home Uncategorized Cancer risks ...

Cancer risks associated with X-rays, CT scans are only theoretical: Study

0
//
84
Republish
Reprint

New York: The widespread belief that radiations from X-rays and CT scans can cause cancer has flaws and is based on an unproven theoretical model, suggests a study.

To estimate cancer risk from low-dose radiation, scientists used a model known as linear no-threshold (LNT) in the study published in the American Journal of Clinical Oncology.

But risk estimates based on this model “are only theoretical and, as yet, have never been conclusively demonstrated by empirical evidence”, wrote researcher James Welsh from the Loyola University in Chicago.

The use of the LNT model drives unfounded fears and “excessive expenditures on putative but unneeded and wasteful safety measures”, Welsh noted.

In the LNT model, the well-established cancer-causing effects of high doses of radiation are extended downward in a straight line to very low doses.

The model dissuades many physicians from using appropriate imaging techniques and “discourages many in the public from getting proper and needed imaging, all in the name of avoiding any radiation exposure”, the researcher explained.

This model assumes there is no safe dose of radiation, no matter how small.

However, the human body has evolved the ability to repair damage from low-dose radiation that naturally occurs in the environment.

Studies of atomic bomb survivors and other epidemiological studies of human populations have never conclusively demonstrated that low-dose radiation exposure can cause cancer, according to the study.

Any claim that low-dose radiation from medical imaging procedures is known to cause cancer “should be vigorously challenged, because it serves to alarm and perhaps harm, rather than educate”, the scientists suggested.

The LNT model “should finally and decisively be abandoned”, the authors concluded. (IANS)(Photo: www.continentalhospitals.com)

Click here for reuse options!
Copyright 2016 NewsGram

Next Story

Researchers Unveil the Power of Turmeric in Fighting Cancer

Curcumin is also known to exhibit anti-cancer properties, but its poor solubility in water had impeded curcumin's clinical application in cancer

0
Cancer
Indian-American researchers unleash turmeric's power to fight cancer. Pixabay

A team of Indian-American researchers at the University of Illinois at Urbana-Champaign (UIUC) and at the University of Utah at Salt Lake City, has used an ingenious process to enable curcumin to kill cancer cells.

Curcumin is the active ingredient of turmeric (haldi), the ubiquitous kitchen spice that gives curry its yellow color. Turmeric has been used in India for thousands of years as a spice and medicinal herb because of its powerful anti-inflammatory and strong antioxidant property.

Curcumin is also known to exhibit anti-cancer properties, but its poor solubility in water had impeded curcumin’s clinical application in cancer. A drug needs to be soluble in water as otherwise it will not flow through the bloodstream.

Despite decades of research, the development of efficient strategies that can effectively deliver poorly water-soluble curcumin to cancer cells had remained a challenge.

A team headed by Dipanjan Pan, associate professor of bioengineering at UIUC, has now found a way out.

“Curcumin’s medicinal benefit can be fully appreciated if its solubility issue is resolved,” Pan told this correspondent in an e-mail.

turmeric
Indian-American researchers unleash turmeric’s power to fight cancer. Pixabay

Pan’s laboratory collaborated with Peter Stang at the University of Utah on ways to be able to render curcumin soluble, deliver it to infected tumors and kill the cancer cells.

Because platinum is a commonly used cancer therapeutic agent in the clinic, the researchers decided to experiment with a drug consisting of a combination of platinum and curcumin.

“It is a combination of clever chemistry and nano-precipitation utilising host guest chemistry,” Pan explained. “The sophisticated chemistry leads to self-assembled hierarchical structure that drives the solubility of curcumin and simultaneously delivers an additional anticancer agent, i.e. platinum. The combined therapeutic effect — of curcumin and platinum — is lethal for the cancer cells.”

The team has reported its work in the “Proceedings of the National Academy of Sciences” in the US.

According to their report, the metallocyclic complex created using platinum “not only enabled curcumin’s solubility, but proved to be 100 times more effective in treating various cancer types such as melanoma and breast cancer cells than using curcumin and platinum agents separately”.

You May Also Wish to Read- 6 mn Indians Can be Helped With Advanced Low-Vision Aid

“Our results demonstrate that curcumin works completely in sync with platinum and exerts synergistic effect to show remarkable anticancer properties,” says the report. “The platinum-curcumin combination kills the cells by fragmenting its DNA.”

“Extensive animal studies are in progress in my laboratory, including in rodents and pigs,” Pan said. His team also hopes to prove that this method will be effective in killing cancer stem cells — the birth place of cancer cells — thereby preventing the recurrence of cancer.

Pan’s team included post-doctoral researcher Santosh Misra at UIUC, and Sougata Datta, Manik Lal Saha, Nabajit Lahiri, Janis Louie, and Peter J. Stang from the University of Utah. (IANS)