A cannabis-based drug may help ease muscle movement for people suffering from motor neuron disease, the results of a clinical trial have shown.
The study, published in The Lancet Neurology journal, showed that chemical compounds — delta-9 tetrahydrocannabinol THC and cannabidiol (THC-CBD) — derived from the cannabis sativa plant given as an add-on treatment may help ease symptoms of spasticity (tight or stiff muscles).
Spasticity is a rapidly progressive, fatal neurodegenerative disorder affecting the nerve cells that control muscle movement. It is a major cause of disability and reduced quality of life in people with motor neuron disease.
Adults with motor neuron disease who took a combination of anti-spasticity drugs and cannabidiol experienced less spasticity and pain at six weeks follow-up compared with those given placebo.
“There is no cure for motor neuron disease so improved symptom control and quality of life are important for patients,” said lead researcher Nilo Riva from the San Raffaele Scientific Institute in Italy.
“Our trial showed a beneficial effect of THC-CBD spray in people on treatment-resistant spasticity and pain,” Riva added.
However, there is a need to confirm efficacy and safety of THC-CBD spray in larger, longer term phase 3 trials, Riva said.
For the trial, the team included 60 adults (aged 18-80 years).
The cannabis plant is replete with a type of cannabinoid called phytocannabinoids. However, the term cannabinoid actually refers to a class of chemicals that act on cannabinoid receptors. Even so, cannabinoids are not exclusive to cannabis. To mess it up even more, there are three different types of cannabinoids, depending on the origin. The basic principle of cannabinoids can be summarized below:
Cannabinoids are chemical compounds. They owe their name to the way they catalyze various biological responses of cannabinoid receptors. And although cannabinoids are very present in cannabis, they are also found in other plants, produced internally by animals and humans, and can even be synthesized in laboratories. You may be surprised to learn that cannabinoids are present in mammals, birds, fish, reptiles and in the anthropoids of all life (that is, us, humans). It is estimated that cannabinoid receptors have existed in these creatures for more than 500 million years, when evolution allowed the transition from life in the ocean to the earth. If the first animals that walked the earth evolved to have cannabinoid receptors, it is very likely that they were vital for their survival. After all, the Fanerozoic Eon (530 million years ago) was a period of time based on the spirit of “the law of the strongest”.
Canabidiol (or CBD) – Why Does It Only Grow Up?
Proponents of cannabis have long talked about its medicinal benefits, but some potential uses of the plant are surprising. Its consumption worldwide is constantly on the rise and promises to revolutionize medicine as we know it, especially with the use of cannabidiol (CBD). But what is canabidiol? It is a chemical of the plant Cannabis sativa, also known as marijuana. More than 80 chemicals, known as cannabinoids, have been identified in this plant. Although delta-9-tetrahydrocannabinol (THC) is the main active ingredient, cannabidiol makes up about 40% of cannabis extracts and has been studied for many different uses. One of the most important qualities of CBD, as it is known, is the lack of interference in psychic activity, as it is free from THC. In layman’s terms, this means that cannabidiol will not leave you “stoned”, which is one of the reasons for its release in several countries. People take cannabidiol, orally, to fight anxiety, bipolar disorder, dystonia, epilepsy, multiple sclerosis, Parkinson’s disease and schizophrenia. A prescription nasal spray (Sativex, from GW Pharmaceuticals) containing THC and cannabidiol is used for muscle pain and stiffness in people with multiple sclerosis in more than 25 countries.
In addition to helping treat these diseases, clinical scientific research ensures that CBD is also effective against arthritis, diabetes, alcoholism, chronic pain, post-traumatic stress disorder, depression, antibiotic-resistant infections and some neurological disorders. Some preclinical studies have shown that cannabidiol has a large antitumor property. The most important research to reveal these powerful tumor-inhibiting effects came in 2015 and concluded that “CBD slows the progression of many types of cancer, including breast, lung, prostate and colon cancers.” Cannabidiol hinders the growth of cancer cells, sometimes favoring their elimination. Therefore, it is not surprising that there are many stories about “miracle” cures with the use of CBD.
Now is the right time!
Is it time to think outside the box and open the range of benefits that this medicinal plant can bring? Countries around the world have already legalized their medicinal and recreational use, agreeing that the luminous side is infinitely greater than the dark side. It would have to be withdrawn from the hands of the traffickers and brought to the population the knowledge and support needed so that their use is always done in a responsible and conscious way.
But how to consume the CBD safely?
There are several ways to consume CBD at safe doses and CBD oil is the most common version. You can consume it in the form of oils, vapes and even edibles. Many CBD brands offer the best products but not all of them are truly reliable. In our observation, there are only a handful of brands that can truly guarantee that each product presented is in a safe dose.
The best CBD edible brand that we recommend is Diamond CBD. This is an American brand that presents a variety of CBD products that are safe for consumption. You can find whatever you are looking for; oils, vapes, edibles, drinks, creams and so on.
Diamond CBD edibles
Diamond CBD provides a variety of flavors and edibles formulas. They include CBD gummies, CBD chocolates, CBD shots all of which have been infused with CBD Hemp Oil. Forget the old ways to get extra marijuana because you can enjoy it in the same way when you eat your favorite cake.
For sale at a price range of less than $ 50.00, Diamond CBD edibles are the answer for anyone who wants to benefit from CBD in fun ways. There are many edible products available; Relax Gummies – CBD Infused Watermelon Slices, Relax Gummies – CBD Infused Gummy Bears Sugar Free, Chill Plus Gummies – CBD Infused Watermelon Slices, Liquid Gold Gummies Sweet Mix and so on. Each product is unique, has a distinctive taste and is adapted for various consumer segments. For diabetics, consuming sugar-free products is recommended. As for those who like the taste of fresh fruits, the taste of watermelon will fulfill their desires.
Diamond CBD ensures every product is made in the USA, which means that they have all passed the strict requirements of the FDA. CBD is a glimmer of hope to change the bad stereotypes that have been borne by cannabis.