Wednesday October 17, 2018

Cannabis can help heal bone fractures

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London: Use of an anti-inflammatory compound found in cannabis significantly helps heal bone fractures, a study says. cannabis_sativa_young_flower_top_by_transmitdistort-d5b6vp6

The study, conducted on rats with mid-femoral fractures, found that administration of the non-psychotropic component cannabinoid cannabidiol (CBD) markedly enhanced the healing process of the femora after just eight weeks.

“We found CBD alone to be sufficiently effective in enhancing fracture healing,” said one of the lead researchers Yankel Gabet from Tel Aviv University in Israel.

Cannabis, also known by the names marijuana and hashish — was used as a go-to medical remedy by societies around the world for centuries. But the therapeutic use of marijuana was banned in most countries in the 1930s and ’40s due to a growing awareness of the dangers of addiction.

The significant medical benefits of marijuana in alleviating symptoms of such diseases as Parkinson’s, cancer, and multiple sclerosis have only recently been re-investigated.

In the new study published in the Journal of Bone and Mineral Research, the researchers injected one group of rats with CBD alone and another with a combination of CBD and tetrahydrocannabinol (THC), the major psychoactive component of cannabis.

After evaluating the administration of THC and CBD together in the rats, they found CBD alone provided the necessary therapeutic stimulus.

“We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue,” Gabet said.

“After being treated with CBD, the healed bone will be harder to break in the future,” he said.

“Other studies have also shown CBD to be a safe agent, which leads us to believe we should continue this line of study in clinical trials to assess its usefulness in improving human fracture healing,” Gabet said.

The findings could lead to use of cannabinoid drugs to combat osteoporosis and other bone-related diseases.

(IANS)

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Cannabis Use Has Lasting Effects on Cognitive Skills in Teenagers Than Alcohol

Moreover, these increased with cannabis use and also were long-lasting compared to alcohol

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While both alcohol and marijuana misuse are known to be associated with impairments in learning, memory, attention and decision-making, as well as with lower academic performance, a new study claimed that cannabis use has lasting effects on cognitive skills in teenagers than alcohol.

The findings, led by researchers at Universite de Montreal, showed cannabis affected cognitive functions such as perceptual reasoning, memory recall, working memory and inhibitory control.

Moreover, these increased with cannabis use and also were long-lasting compared to alcohol.

“Increases in cannabis use, but not alcohol consumption, showed additional concurrent and lagged effects on cognitive functions such as perceptual reasoning, memory recall, working memory and inhibitory control,” said Patricia Conrod, from the varsity.

“Of particular concern was the finding that cannabis use was associated with lasting effects on a measure of inhibitory control, which is a risk factor for other addictive behaviours, and might explain why early onset cannabis use is a risk factor for other addictions,” added Jean-Francois G. Morin, doctoral student at Montreal.

Cannabis
Cannabis more ‘toxic’ to teenage brains than alcohol: Study. Pixabay

“Some of these effects are even more pronounced when consumption begins earlier in adolescence,” Morin added.

For the study, published in the American Journal of Psychiatry, the team followed a sample of 3,826 Canadian high school students from 7th to 10th grade over a period of four years.

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In a context where policies and attitudes regarding substance use are being reconsidered, this research highlights the importance of protecting youth from the adverse effects of consumption through greater investment in drug-prevention programmes.

“While this study did not detect effects of teenage alcohol consumption on cognitive development, the neurotoxic effects may be observable in specific subgroups differentiated based on the level of consumption, gender or age,” Morin said. (IANS)

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