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Celebrities from Film Industry mourn Veteran Movie Actor Vinod Khanna’s demise, pay tributes to him

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Veteran movie actor Vinod Khanna, Twitter

Mumbai, April 27, 2017: Celebrities like Rajinikanth, Asha Bhosle, Rishi Kapoor, Anupam Kher and Shatrughan Sinha have paid tributes to veteran movie actor-politician Vinod Khanna, who died on Thursday after suffering from prolonged illness.

He was hospitalised for over a month over suspected cancer. He was living with his wife, three sons and a daughter.

Khanna was admitted to Sir H.N. Reliance Foundation Hospital in the first week of April after reportedly suffering from severe dehydration.

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The actor was the incumbent Bharatiya Janata Party (BJP) member of the Lok Sabha from Punjab’s Gurdaspur constituency in Punjab.

Here’s what B-Town had to say:

Rajinikanth: My dear friend Vinod Khanna…Will miss you, RIP. My heartfelt condolences to the family.

Asha Bhosle: Very sad to hear about Vinod Khannaji. A decent man and a star till the very end. My condolences to his family.

Rishi Kapoor: Will miss you Amar ( his charcter name from the film ‘Amar Akbar Anthony’). RIP…Remembering the good times with you, Vinod. Thank you for being my friend.

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Anupam Kher: Vinod Khanna ji had a magnetic charm and persona. Both on and off screen. He was kind, affectionate and helpful. Loved his panther like walk.

Karan Johar: His screen presence is unparalleled even today…his super star swag is what we grew up on….RIP Vinod Khanna…thoughts and prayers.

Shatrughan Sinha: Vinod Khanna, truly “Mere Apne”, one of my most admired and loved personalities, the supremely handsome and talented superstar is no more. Right from films to politics, Vinod Khanna and I sailed together and he leaves behind an entire generation & more of fans, admirers..

Akshay Kumar: Sad to learn about the passing away of Vinod Khanna Sir, one of the most charismatic actors…truly end of an era. Condolences to the family

Amjad Ali Khan: Deeply saddened to know about the passing away of Vinod Khanna one of the most charismatic actors of our times. Condolences to the family.

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Varun Dhawan: Vinod Khanna will always remain the coolest and most good looking actor to grace the Indian screens.The industry has lost a legend today.

Manoj Bajpayee: Your charisma and charm will always be unmatchable…will miss your flamboyant walk…Rest in peace sir. Vinod Khanna.

Abhishek Kapoor: Rest in peace Vinod Khanna and thank you for the great memories.

Shraddha Kapoor: One of the most loved, handsome and wonderful actors. Big loss. We have lost a legend today. Will always be a fan. RIP Vinod Khanna.

Hansal Mehta: ‘Ruk Jaana nahi kahin tu haarke…Kaante pe chalke milengay saaye bahaar ke….oh rahi oh rahi’… RIP Vinod Khanna.

Huma Qureshi: RIP. Vinod Khanna.

Anubhav Sinha: Much before we knew the word Swag, he had it. Go Well Sir. Enjoy your new Journey. We will miss you. Vinod Khanna

Manisha Koirala: Unbelievable loss! Heartfelt condolences to the family on the passing away of one of the most charismatic actors Vinod Khanna ji.

Abhishek Kapoor: Rest in peace Vinod Khanna and thank you for the great memories.

Ehsaan Noorani: Saddened to hear about the passing of Vinod Khanna one of my favourite actors and a family friend… immortalised forever in memory.

Sajid Khan: R.I.P. Vinodji…Thanks for your contribution to mainstream cinema…thanks for all the memories of cinema magic. Vinod Khanna amar hai.

Goldie Behl: RIP…Vinod Khanna legend one of my favourite and the best walk on screen.

Richa Chadha: RIP Vinod Khanna sir. You were the fantasy of most women in the northern India through the 1980s. You shall be missed by one and all.

Sujoy Ghosh: My dad made me see a film called ‘Patthar Aur Payal’…I came out becoming a fan of the villain. Thank you Vinod Khanna for the films.

Esha Deol: Extremely saddened by the news of my darling uncle Vinod Khanna passing away. Our condolences to his family! May his soul RIP.

Armaan Malik: Rest in peace Vinod Khanna. You were Amar, you are Amar will always remain Amar for all of us in our hearts.

Raghu Ram: R.I.P Vinod Khanna sir! What an adventurous life lived! Wish strength to his family.

Sophie Choudry: Deepest condolences to the family.. His incredible movies and film songs will forever be etched in our hearts…Matinee idol RIP Vinod Khanna.

Sikandar Kher: The loss of a legend…May you make all the women swoon up there amongst the stars.. strength to the family. Vinod Khanna. (IANS)

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Genetic Variations Influence Risk of Developing Cancer: Study

Study found that variations in the regions that regulate the expression of oncogenes and tumour suppressor genes affect cancer risk

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While minor genetic changes only have a small impact on Cancer risk, the variations analysed in this study are numerous and common in the population. Pixabay

Shedding new light on why some people develop cancer while others do not, a new study has found that a person’s risk of developing cancer is affected by Genetic variations in regions of DNA that do not code for proteins, previously dismissed as “junk DNA”.

This study, published in the British Journal of Cancer, shows that inherited cancer risk is not only affected by mutations in key cancer genes, but that variations in the DNA that controls the expression of these genes can also drive the disease.

The researchers believe that understanding how non-coding DNA affects the development of this disease could one day improve genetic screening for cancer risk.

And in the future, this could lead to new prevention strategies, or help doctors diagnose the disease earlier, when it is more likely to be treated successfully.

“What we found surprised us as it had never been reported before — our results show that small genetic variations work collectively to subtly shift the activity of genes that drive cancer,” said lead researcher of the study John Quackenbush, Professor at Harvard T.H. Chan School of Public Health in the US.

Genetic
Shedding new light on why some people develop Cancer while others do not, a new study has found that a person’s risk of developing cancer is affected by genetic variations in regions of DNA that do not code for proteins, previously dismissed as “junk DNA”. Pixabay

“We hope that this approach could one day save lives by helping to identify people at risk of cancer, as well as other complex diseases,” Quackenbush said.

The researchers investigated 846 genetic changes within non-coding stretches of DNA, identified by previous studies as affecting cancer risk.

These Single Nucleotide Polymorphisms (SNPs) are particular positions in the human genome where a single letter of the genetic code varies between people.

Unlike mutations in coding DNA, such as BRCA, that are rare but significantly raise a person’s risk of developing cancer, non-coding SNPs are relatively common in the population but only slightly increase cancer risk.

The team analysed whether there was a correlation between the presence of a particular SNP and the expression of particular genes.

In total, they looked at over six million genetic variants across 13 different body tissues.

Genetic
The researchers believe that understanding how non-coding DNA affects the development of this disease could one day improve genetic screening for cancer risk. Pixabay

They found that variations in the regions that regulate the expression of oncogenes and tumour suppressor genes affect cancer risk.

The study also revealed that these cancer-risk SNPs tend to be specifically located in regions that regulate the immune system and tissue-specific processes — highlighting the importance of these cellular processes to the development of cancer.

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“While minor genetic changes only have a small impact on cancer risk, the variations analysed in this study are numerous and common in the population,” said Emily Farthing, senior research information manager at British charity Cancer Research UK. (IANS)