Saturday June 23, 2018

Cheap anti-inflammatory Drug for Common Cold can Stop Spread of Cancer, say Japanese Researchers

The study conducted using animal model showed that injecting flufenamic acid a much cheaper cold drug into cancerous bladder cells can suppress the cells

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Tokyo, October 18, 2016: A non-steroid, anti-inflammatory drug used for treating common cold has the potential to suppress the spread of bladder cancers as well as reduce their resistance to anti-cancer drugs in mice, Japanese researchers have found.

Bladder cancer — the seventh most common cancer in males worldwide — can be grouped into two types: non-muscle-invasive cancer, which has a five-year survival rate of 90 percent, and muscle-invasive cancer, which have poor prognoses.

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The latter are normally treated with such anti-cancer drugs as cisplatin, but tend to become chemo-resistant and, thus, spread to organs such as the lungs and liver, as well as bone, the study said.

The study conducted using animal model showed that injecting flufenamic acid — a much cheaper cold drug — into cancerous bladder cells can suppress the cells’ invasive activities and restore the effectiveness of anti-cancer drugs.

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“The study could pave the way for medical institutions to use flufenamic acid which has unexpectedly been proven to be effective at fighting cancers,” said Shinya Tanaka from Hokkaido University in Japan.

In the study, using rats the team created a xenograft bladder cancer model and discovered a three to 25-fold increase of the metabolic enzyme aldo-keto reductase 1C1 (AKR1C1).

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It was also identified for the first time that AKR1C1 enhances tumour-promoting activities and proved the enzyme blocks the effectiveness of cisplatin and other anti-cancer drugs, which can be inhibited by flufenamic acid, the researchers concluded in the paper published in the journal Scientific Reports. (IANS)

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  • Ruchika Kumari

    Japanese Researchers have done good job. A proper campaign is much needed so more and more people come to know about this research.

  • Antara

    Hope it really works!

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FIFA World Cup 2018: Indian Cuisine becomes the most sought after in Moscow

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Indian cuisine in FIFA World cup
Indian dishes available in Moscow during FIFA World Cup 2018, representational image, wikimedia commons

June 17, 2018:

Restaurateurs Prodyut and Sumana Mukherjee have not only brought Indian cuisine to the ongoing FIFA World Cup 2018 here but also plan to dish out free dinner to countrymen if Argentina wins the trophy on July 15.

Based in Moscow for the last 27 years, Prodyut and Sumana run two Indian eateries, “Talk Of The Town” and “Fusion Plaza”.

You may like to read more on Indian cuisine: Indian ‘masala’, among other condiments spicing up global food palate.

Both restaurants serve popular Indian dishes like butter chicken, kebabs and a varied vegetarian spread.

During the ongoing FIFA World Cup 2018, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

The Mukherjees, hailing from Kolkata, are die-hard fans of Argentina. Despite Albiceleste drawing 1-1 with Iceland in their group opener with Lionel Messi failing to sparkle, they believe Jorge Sampaoli’s team can go the distance.

“I am an Argentina fan. I have booked tickets for a quarterfinal match, a semifinal and of course the final. If Argentina goes on to lift

During the World Cup, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

FIFA World Cup 2018 Russia
FIFA World Cup 2018, Wikimedia Commons.

“We have been waiting for this World Cup. Indians come in large numbers during the World Cup and we wanted these eateries to be a melting point,” he added.

According to Cutting Edge Events, FIFA’s official sales agency in India for the 2018 World Cup, India is amongst the top 10 countries in terms of number of match tickets bought.

Read more about Indian cuisine abroad: Hindoostane Coffee House: London’s First Indian Restaurant.

Prodyut came to Moscow to study engineering and later started working for a pharmaceutical company here before trying his hand in business. Besides running the two restaurants with the help of his wife, he was into the distribution of pharmaceutical products.

“After Russia won the first match of the World Cup, the footfall has gone up considerably. The Indians are also flooding in after the 6-9 p.m. game. That is the time both my restaurants remain full,” Prodyut said.

There are also plans to rope in registered fan clubs of Latin American countries, who will throng the restaurants during matches and then follow it up with after-game parties till the wee hours.

“I did get in touch with some of the fan clubs I had prior idea about. They agreed to come over and celebrate the games at our joints. Those will be gala nights when both eateries will remain open all night for them to enjoy,” Prodyut said.

Watching the World Cup is a dream come true for the couple, Sumana said.

“We want to make the Indians who have come here to witness the spectacle and feel at home too. We always extend a helping hand and since we are from West Bengal, we make special dishes for those who come from Bengal,” she added. (IANS)