Wednesday September 19, 2018

Cheap anti-inflammatory Drug for Common Cold can Stop Spread of Cancer, say Japanese Researchers

The study conducted using animal model showed that injecting flufenamic acid a much cheaper cold drug into cancerous bladder cells can suppress the cells

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Tokyo, October 18, 2016: A non-steroid, anti-inflammatory drug used for treating common cold has the potential to suppress the spread of bladder cancers as well as reduce their resistance to anti-cancer drugs in mice, Japanese researchers have found.

Bladder cancer — the seventh most common cancer in males worldwide — can be grouped into two types: non-muscle-invasive cancer, which has a five-year survival rate of 90 percent, and muscle-invasive cancer, which have poor prognoses.

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The latter are normally treated with such anti-cancer drugs as cisplatin, but tend to become chemo-resistant and, thus, spread to organs such as the lungs and liver, as well as bone, the study said.

The study conducted using animal model showed that injecting flufenamic acid — a much cheaper cold drug — into cancerous bladder cells can suppress the cells’ invasive activities and restore the effectiveness of anti-cancer drugs.

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“The study could pave the way for medical institutions to use flufenamic acid which has unexpectedly been proven to be effective at fighting cancers,” said Shinya Tanaka from Hokkaido University in Japan.

In the study, using rats the team created a xenograft bladder cancer model and discovered a three to 25-fold increase of the metabolic enzyme aldo-keto reductase 1C1 (AKR1C1).

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It was also identified for the first time that AKR1C1 enhances tumour-promoting activities and proved the enzyme blocks the effectiveness of cisplatin and other anti-cancer drugs, which can be inhibited by flufenamic acid, the researchers concluded in the paper published in the journal Scientific Reports. (IANS)

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  • Ruchika Kumari

    Japanese Researchers have done good job. A proper campaign is much needed so more and more people come to know about this research.

  • Antara

    Hope it really works!

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Aadhaar Helpline Mystery: French Security Expert Tweets of doing a Full Disclosure Tomorrow about Code of the Google SetUP Wizard App

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Google's new tool can help you make our planet healthy. Wikimedia Commons

Google’s admission that it had in 2014 inadvertently coded the 112 distress number and the UIDAI helpline number into its setup wizard for Android devices triggered another controversy on Saturday as India’s telecom regulator had only recommended the use of 112 as an emergency number in April 2015.

After a large section of smartphone users in India saw a toll-free helpline number of UIDAI saved in their phone-books by default, Google issued a statement, saying its “internal review revealed that in 2014, the then UIDAI helpline number and the 112 distress helpline number were inadvertently coded into the SetUp wizard of the Android release given to OEMs for use in India and has remained there since”.

Aadhaar Helpline Number Mystery: French security expert tweets of doing a full disclosure tomorrow about Code of the Google SetUP Wizard App, Image: Wikimedia Commons.

However, the Telecom Regulatory Authority of India (TRAI) recommended only in April 2015 that the number 112 be adopted as the single emergency number for the country.

According to Google, “since the numbers get listed on a user’s contact list, these get  transferred accordingly to the contacts on any new device”.

Google was yet to comment on the new development.

Meanwhile, French security expert that goes by the name of Elliot Alderson and has been at the core of the entire Aadhaar controversy, tweeted on Saturday: “I just found something interesting. I will probably do full disclosure tomorrow”.

“I’m digging into the code of the @Google SetupWizard app and I found that”.

“As far as I can see this object is not used in the current code, so there is no implications. This is just a poor coding practice in term of security,” he further tweeted.

On Friday, both the Unique Identification Authority of India (UIDAI) as well as the telecom operators washed their hand of the issue.

While the telecom industry denied any role in the strange incident, the UIDAI said that he strange incident, the UIDAI said that some vested interests were trying to create “unwarranted confusion” in the public and clarified that it had not asked any manufacturer or telecom service provider to provide any such facility.

Twitter was abuzz with the new development after a huge uproar due to Telecom Regulatory Authority of India (TRAI) Chairman R.S. Sharma’s open Aadhaar challenge to critics and hackers.

Ethical hackers exposed at least 14 personal details of the TRAI Chairman, including mobile numbers, home address, date of birth, PAN number and voter ID among others. (IANS)

Also Read: Why India Is Still Nowhere Near Securing Its Citizens’ Data?