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Delhi hospital treats 41-year-old man with extremely rare tumour-induced Bone condition

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Operating theatre in India, Wikimedia Commons
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New Delhi, March 5, 2017: Doctors here have successfully treated a 41-year-old man with an extremely rare tumour-induced condition that caused bone fragility, fractures and left him wheelchair-bound.

Tumour-induced osteomalacia is an extremely rare disorder where benign small soft tissue or bone tumours develop in the body and start secreting a substance that inhibits the absorption of phosphates, causing a cascade of biochemical abnormalities including extremely fragile bones.

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“So rare is this condition that many doctors fail to get to the root of it. A majority of these tumours are located in the extremities (skin, muscles, and bones) or around the head, but they may occur in almost any part of the body. These tumours are slow growing and often remain hidden or undetected until clinical features reach a fairly advanced stage,” Endocrinologist at Venkateshwar Hospital in Dwarka Deep Dutta said in a statement on Saturday.

Progressive weakness in legs over three years coupled with a fracture had left Ravi Sharma (name changed) wheelchair-bound.

Doctors found that he had extremely low serum levels of phosphorus (1mg/dl) — key structural component of bone apart from calcium — in urine, which led to skeletal weakness and fractures.

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An FDG (fluorodeoxyglucose)-PET scan confirmed the presence of tumour-induced osteomalacia at the lower end of the femur bone and later a CT-scan revealed an extremely small lesion of 1 cm diameter, and was successfully removed by the doctors.

“Within 24 hours of surgery, we found the patient’s phosphorus levels improved to 3.3mg/dl, and he regained his physical strength and was able to start walking with support. We have reduced Ravi’s oral phosphate replacement dose significantly and we expect he will be totally off phosphate replacement in the next few days. All biochemical and clinical features reverted to normal when the tumour was removed,” Dutta said. (IANS)

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Sudan Suffers From A Chikungunya Outbreak

Activists on social media said the number of people infected by the disease was much higher than the government's figure and that there had been deaths not documented by the government.

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A woman sits inside a mosquito tent in the town of Abyei, Sudan. VOA

More than 11,000 people in Sudan’s eastern state of Kassala have been infected over the past month by Chikungunya, a debilitating mosquito-borne viral disease, but no deaths have been reported, a Sudanese official said Tuesday.

Chikungunya is spread by two mosquito species and can cause severe symptoms, which develop three to seven days after a person is bitten by an infected mosquito. They include high fever, headache, muscle pain, back pain and rash. In rare cases, it is fatal. There are no dedicated treatments or vaccines for Chikungunya.

“So far official statistics say that about 11,000 people were infected, and there haven’t been any documented cases of death because of the Chikungunya fever,” said Magzoub Abou Moussa, a spokesman for the Kassala state administration.

Chikungunya
Omar al Bashir, President of Sudan, wikimedia commons

Heavy rains

The outbreak began in recent weeks when heavy rains pummeled the area, which led to the flooding of a major river in Kassala.

Abou Moussa said his state had received health and technical aid from Sudan’s health ministry, but expressed concern over the spread of the virus and called for further help.

Eyewitnesses said they had seen planes on Monday sweeping over the state, spraying mosquito pesticides.

Sudanese opposition parties have accused the government of failing to deal with the situation in Kassala and called for international organizations’ help.

chikungunya
Women sit in line on the ground waiting to receive food distributed by the World Food Program (WFP) in Padeah, South Sudan, March 1, 2017. VOA

“We hold the government fully responsible for the spread of the epidemic,” said a statement from the National Umma Party, the largest opposition party. “We call on civil society organizations and the World Health Organization to help the people of Kassala.”

Also Read: Sudan Stops 13 Diplomatic and 4 Consular Missions Due to Financial Crisis

Activists on social media said the number of people infected by the disease was much higher than the government’s figure and that there had been deaths not documented by the government. (VOA)