Sunday February 17, 2019
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Depressed teenagers at greater heart disease risk

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New York: Major depressive disorder and bipolar disorder predispose youth to early cardiovascular disease, the American Heart Association (AHA) has said. 

The AHA statement is based on a group of recent studies including those that reported cardiovascular events such as heart attacks and deaths among young people.

For example, a 2011 population study of over 7,000 young adults in the US under the age of 30, found that depression or an attempted suicide was the No.1 risk factor for heart disease death caused by narrowed/clogged arteries in young women, and the No.4 risk factor in young men.

“Youth with mood disorders are not yet widely recognized as a group at increased risk for excessive and early heart disease. We hope these guidelines will spur action from patients, families and healthcare providers to reduce the risk of cardiovascular disease among these youth,” said Benjamin I. Goldstein, lead author of the statement.

Since cardiovascular disease may begin early in life, the authors want to increase awareness and recognition of mood disorders among young people as moderate-risk conditions for early cardiovascular disease.

After systematically analyzing published research, the authors found that teens with major depression or bipolar disorder are more likely than other teens to have several cardiovascular disease risk factors including high blood pressure, high cholesterol, obesity and type-2 diabetes.

“Mood disorders are often lifelong conditions, and managing cardiovascular risk early and assertively is tremendously important if we are to be successful in ensuring that the next generation of youth has better cardiovascular outcomes,” Goldstein, a child-adolescent psychiatrist, said.

The findings were published in Circulation, a journal of the American Heart Association.

(IANS)

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Study Finds, Statins Can Prevent Neurological Disorder Development

For the study, the team of researchers searched genetic datasets of around 25 million people to find risk factors for developing ALS.

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Neurological disorder
Statins, if clinically tested, could be used to prevent the development of MND, the researchers said. Pixabay

Besides treating heart disease, cholesterol-lowering drugs statins can also be used to prevent the development of a neurodegenerative disease, finds a study.

According to the study by Queen Mary University of London (QMUL) researchers, high cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND) — a non-curable disease that affects the brain and nerves and is also known as Amyotrophic lateral sclerosis (ALS).

The symptoms include weakness, indistinct speech, difficulty in swallowing food, muscle cramps and more. In some cases, people experienced changes in their thinking and behaviour.

“We saw that higher levels of LDL cholesterol (the “bad” cholesterol) were causally linked with a greater risk of the disease,” said Alastair Noyce from the varsity.

Heart disease, Neurological
For the study, published in journal “Annals of Neurology”, the team of researchers searched genetic datasets of around 25 million people to find risk factors for developing ALS. Pixabay

“We have well-established drugs that can lower cholesterol and we should look into whether they could protect against this terrible disease, which currently has no cure,” Noyce added.

For the study, published in journal “Annals of Neurology”, the team of researchers searched genetic datasets of around 25 million people to find risk factors for developing ALS.

In addition to the causal effect of high cholesterol, they also found genetic associations with smoking behaviour and lower levels of educational achievement, and an increased risk of ALS.

While low levels of exercise were associated with a protective effect, more aggressive exercise was associated with increased risk.

Neurological disorder, statins
Cholesterol-lowering drugs statins can also be used to prevent the development of a neurodegenerative disease. VOA

However, of these findings, only high cholesterol emerged as a clear modifiable factor that could be targeted to reduce the risk of MND.

ALSO READ: Study Claims, There Should Be Treatment Options Given for Miscarriage

Statins, if clinically tested, could be used to prevent the development of MND, the researchers said.

“The next steps will include studying whether lowering levels of cholesterol might have a protective effect against MND, and potentially evaluating the use of cholesterol-modifying drugs in people at risk of MND,” Noyce noted. (IANS)