Tuesday April 24, 2018

EDM party-goers at high opioid dependence risk

Opioid use has grown to epidemic proportions in the US and has been the main contributor to a resurgence of heroin use as well as the spread of HIV and Hepatitis C

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EDM party-goers are more likely to use drugs. IANS
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  • EDM party goers are known to use many drugs
  • They also misuse opioids like heroin
  • The dance party goers are always at a higher risk of using drugs

Not just common party drugs like ecstasy, more and more electronic dance music (EDM) party attendees are misusing opioids like heroin, researchers claim.

Opioid use has grown to epidemic proportions in the US and has been the main contributor to a resurgence of heroin use as well as the spread of HIV and Hepatitis C, the team from New York University said.

Drugs, Rehabilitation centre
Party goers are misusing opioids like heroin. Pixabay

“We’ve always known that electronic dance music party attendees are at high risk for use of club drugs such as ecstasy or Molly, but we wanted to know the extent of opioid use in this population,” said Joseph Palamar, Associate Professor at New York University.

“This population of experienced drug users needs to be reached to prevent initiation and continued use, which can lead to riskier and more frequent use, dependence, and deleterious outcomes such as overdose – particularly if opioids are combined with other drugs,” Palamar added.

Also Read: Indonesia’s War on Drugs Follows Philippines’ Infamous Crusade to Curb Drug Use

To reach this conclusion, the researchers surveyed 954 individuals (ages 18 to 40) about to enter EDM parties at nightclubs and dance festivals in New York City. Attendees were asked about the use of 18 different opioids — including OxyContin, Percocet, Vicodin, codeine, fentanyl and heroin.

Cocaine
these drugs are causing health issues like HIV and hepatitis C. Wikimedia Commons

The researchers found that almost a quarter (23.9 per cent) of EDM party attendees have used opioids non-medically in their lifetime and one out of 10 (9.8 per cent) did so in the past year. IANS

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Newly Developed Tool to Battle HIV in Women

This novel tool may soon help women to combat HIV transmission

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HIV Aids is a deadly disease.
HIV AIDS

Scientists have developed a new tool that can potentially help protect women from being infected with the human immunodeficiency virus (HIV).

The tool — a vaginal implant — decreases the number of cells that the HIV virus can target in a woman’s genital tract.

Unlike conventional methods of HIV prevention such as condoms or anti-HIV drugs, the novel implant takes advantage of some people’s natural immunity to the virus.

The deadly disease of HIV is now preventable.
HIV is now preventable.

HIV infects the body by corrupting T-cells that are mobilised by the immune system when the virus enters a person’s body.

“We know that some drugs taken orally never make it to the vaginal tract, so this implant could provide a more reliable way to encourage T-cells not to respond to infection and therefore more reliably and cheaply prevent transmission,” said Emmanuel Ho, professor at the University of Waterloo in Canada.

When the T-cells stay resting and do not attempt to fight the virus they are not infected and the HIV virus is not transmitted between people.

When the T-cells stay resting, it is referred to as being immune quiescent.

However, “what we don’t know yet is if this can be a stand-alone option for preventing HIV transmission or if it might be best used in conjunction with other prevention strategies”, Ho added, in a paper appearing in the Journal of Controlled Release.

Also Read: Severe Symptoms Of Menopause Might Soar The Risk Of Heart Diseases In Women

The implant is composed of a hollow tube and two pliable arms to hold it in place.

It contains hydroxychloroquine (HCQ) which is disseminated slowly through the porous material of the tube and absorbed by the walls of the vaginal tract.

The implants were tested in an animal model and a significant reduction in T-cell activation was observed, meaning that the vaginal tract was demonstrating an immune quiescent state, the researchers said.  IANS

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