Friday November 24, 2017

Exercise may mitigate side-effects of Hormone-therapy Drugs that significantly reduce risk of Breast Cancer

AIs treatment can be a double-edged sword because they often lead to bone loss or severe joint pain, especially if the survivors are obese or overweight

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FILE - A biotechnician demonstrates the loading of a genome sequencing machine at the J. Craig Venter Institute in Rockville, Maryland. Relative to their ability to pay, cancer patients in China and India face much higher prices than wealthier U.S. patients. VOA

New York, Jan 19, 2017: A combination of weight training and 150 minutes of moderate aerobic activity — such as brisk walking or jogging — every week may help mitigate the side-effects of hormone-therapy drugs that significantly reduce the risk of breast cancer recurrence in post-menopausal survivors, shows a recent study.

Because most breast cancers are hormone receptor-positive — that is, they use estrogen or progesterone to grow and spread — survivors often rely on hormone therapy, such as Aromatase Inhibitors (AIs), to keep the disease from returning.

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However, this AIs treatment can be a double-edged sword because they often lead to bone loss or severe joint pain, especially if the survivors are obese or overweight.

“These changes put women at risk for frailty fractures and osteoporosis, not to mention further risk for comorbid chronic disease and cancer reoccurrence,” said Gwendolyn Thomas, assistant professor at Syracuse University in New York, US.

Hence, nearly 40 per cent of survivors stop taking AIs long before their customary five-year treatment period expires and increase the chances of their breast cancer re-occurring, Gwendolyn said.

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Interventions that address obesity in women taking AIs can help them continue this necessary treatment, the researchers continued.

For the study, participants did two sessions of weight training and 150 minutes of moderate aerobic activity, such as brisk walking or jogging, every week for a year.

“We noticed a drop in per cent body fat and body mass index, as well as a significant increase in their lean body mass. These changes have clinical benefits, but also suggest that exercise should be prescribed in conjunction with AIs, as part of a regular treatment regimen,” Thomas said.

The study was published in the Obesity Journal. (IANS)

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Reduce the Spread of Cancer With this Protein, According to Research by University of Guelph, Ontario

Researchers have discovered a new protein that could reduce the spread of cancer by binding the cancer cells together and allowing them to invade tissues

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Fight Cancer
Fight Cancer with this Protein. IANS.

New York, Nov 19: Researchers have discovered a new protein that could reduce the spread of cancer by binding the cancer cells together and allowing them to invade tissues.

The study conducted by the researchers from University of Guelph, Ontario, has identified a protein called cadherin-22, a potential factor in cancer metastasis or the spread of cancer.

The protien also decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

“Cadherin-22 could be a powerful prognostic marker for advanced cancer stages and patient outcomes,” said lead author Jim Uniacke, a professor at the varsity.

“If you can find a treatment or a drug that can block cadherin-22, you could potentially prevent cancer cells from moving, invading and metastasizing.”

The study, published in the journal Oncogene, looks specifically at hypoxia, a condition in which the tissues receive less oxygen.

The researchers found that it is precisely under conditions of low oxygen that cancer cells trigger the production of cadherin-22, putting in motion a kind of protein boost that helps bind cells together, enhancing cellular movement, invasion and likely metastasis.

Studying breast and brain cancer cells in a hypoxia incubator, the researchers discovered that cadherin-22 is involved in this process to enable the spread of cancer cells.

For both cancer types, the research team used molecular tools to reduce the amount of cadherin-22.

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour. The cells failed to spread.

“One very powerful and common tool in cell and molecular biology labs is, you can remove a protein from a cell and see how that cell behaves without it.

“We culture our cancer cells in this very low-oxygen environment, and they start behaving like they are inside a low-oxygen tumour,” Uniacke added. (IANS)

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These 8 successful Muslim women are showcasing Freedom their way!

Though there are forsure many but here we present to you the some handful of success stories of Muslim women in modern world. Totally independant and unbounded, they have carved a niche for themselves in many fields through their creativity, talent and self - belief

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Muslim women
Bashing unfreedom-The new age Muslim woman.Pixeby

Not everyone is following rigid fundamentalism these days. In 2017, people and specially some inspiring Muslim women are embracing freedom and individuality through their inspirational work in global markets. Be it fashion, lifestyle,sports or politics- they are setting standards in every domain, breaking stereotypes all the way long!

Have a look at the success stories of these leading Muslim ladies and what they believe in.

SAUFEEYA GOODSON

Dubai based fashion entrepreneur Saufeeya is a global figure appearing in many fashion magazines. Being the co-owner of Modest Route, she has re- branded Modest fashion in a very stylised manner grabbing the attention of 2million followers on instagram page. She is frequently mentioned in Vogue or Teen Vogue under the trademark of her bold, daring and contemporary outfits made for modern age Muslim woman. This trendsetter with her avant garde style has been revolutionizing Islamic modest clothing in world.

CAROLYN WALKER-DIALLO

Carolyn hit the headlines when she was sworn in with the Quran back in 2015, becoming the first ever New York City Civil court judge to do so. She bravely stood up to the backlash that resulted later but her strong act inspired many Muslim women around the world. It somehow relieved them from communal stigmatization that they go through.

LINDA SARSOUR

Linda Sarsour- civil right's activist
Linda Sarsour- civil right’s activist.wikimedia.commons

 

Linda, a Palestinian- American civil rights activist, is popularly known for her key role in helping to organize the 2017 Women’s March in Washington.It was a public demonstartion led by women coming together from all walks of life. With her resolute, Linda instilled in a belief in thousands of women to fight for their vanity,esteem and rights.

BEHNAZ SHAFIEI

it is hard to imagine a female road racer/motocross rider and being a Muslim woman makes it a rare case, but Behnaz is exactly that. Born in Iran- a country where women are not allowed for exercising such liberties and are often ridiculed for their driving skills, Behnaz enjoys the fact that many men cannot do the stunts she performs with ease and confidence on her motorbike. She is the only Iranian female to be involved in road racing professionally challenging the preconceived notions of the society in regard to women.

RUMA

Known for her fashion blogs, Ruma recently got mentioned on the Twitter page of H&M where she was applauded for her distinctive panache that voice traditional modesty. According to her the haute hijab empowers feminine sensibility.Being a dreamer as well as achiever, she looks forward to inspire her followers with stories and lessons learned from her life by using social media to promote the art of fashion.

HALIMA ADEN

Halima is a model known for being the first Somali-American Muslim woman to take part in a beauty pageant donning a hijab.With all grace and modesty she hit news by reaching the semifinals of Minnesota USA pageant. She even graced the fashion runway for Kanye West at his show Yeezy season 5. Keeping at bay all Muslim stereotypes, this flamboyant model appeared on the front cover of Allure, wearing a Nike hijab with a caption saying, “This is American Beauty.” 

SHAHD BATAL

As a YouTuber and blogger, Shahd’s focus is mainly on providing viewers with her own original tips on how to attain healthy skin or apply makeup. Sudanese by birth but now living in Minneapolis, her tutorial videos are popularly hitting the internet since 2014. They were recently rehashed and showcased via her new sleek channel. From wearing a classic head-wrap and making pen perfect eyebrows, to her very personal stories with regard to the Hijab, she has been earnestly devoting herself to portray Hijab as a motif of modern age accessory.

 

SHARMEEN OBAID-CHINOY     

Muslim Women
SHARMEEN OBAID-CHINOY- Pakistani filmaker.wikimedia.commons

 Sharmeen has been mentioned by esteemed Time magazine as one of the 100 most influential people in the world. A Muslim woman filmmaker, journalist and activist born in Pakistan, most of her films highlight the inequalities that women face. She has received two Academy awards, six Emmy and Lux Style award for her bold vision. Even the Pakistani government has honored her with the second highest civilian honor of the country, the Hilal-i-Imtiaz for her dauntless contribution to films.

These handful examples of empowering, influential and compelling Muslim women express a great deal- to come out of the shackles of a society that restricts you and your creative energies.Not just to the Muslim women of today, they are inspirational for all women who seek for self – actualization.

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Donald Trump Planning to meet Putin during his Asia tour

Donald Trump's first trip to Asia is the longest international tour.

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US President Donald Trump
US President Donald Trump. wikimedia commns
  • US President Donald Trump said on Sunday that he expected to meet his Russian counterpart Vladimir Putin during his Asia tour.

“I think it’s expected we’ll meet with Putin, yeah. We want Putin’s help on North Korea, and we’ll be meeting with a lot of different leaders,” Donald Trump told reporters on Air Force One before landing at the Yokota Air Base in Japan, Efe reported.

Putin is scheduled to participate in the Asia-Pacific Economic Cooperation (APEC) summit in Da Nang, Vietnam, which Trump will also attend as part of his long Asia tour.

The North Korean nuclear threat is expected to dominate Donald Trump’s meetings in Japan and the next two stages of his tour, South Korea and China, where he will have a highly anticipated sit-down with Chinese President Xi Jinping.

The remainder of the tour will be more focused on economic issues, with Trump scheduled to take part in the APEC meeting in Da Nang and then in the Association of Southeast Asian Nations (ASEAN) Summit and the East Asia Summit in the Philippines.

Donald Trump’s first trip to Asia is the longest international tour by a US head of state since the one then-President George H.W. Bush embarked on in 1992.

Bush became ill at the end of that trip, famously vomiting on the Japanese prime minister’s lap at a formal dinner before fainting.(IANS)