Friday February 22, 2019
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First Successful Case Of Womb Transplant in Brazil

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

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Womb Transplant
Medical team hold the first baby born via uterus transplant from a deceased donor at the hospital in Sao Paulo, Brazil. VOA

A woman in Brazil who received a womb transplanted from a deceased donor has given birth to a baby girl in the first successful case of its kind, doctors reported.

The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins, as well as linking arteries, ligaments and vaginal canals.

It comes after 10 previously known cases of uterus transplants from deceased donors – in the United States, the Czech Republic and Turkey – failed to produce a live birth.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams (nearly 6 lbs), the case study said.

Dani Ejzenberg, a doctor at Brazil’s Sao Paulo University hospital who led the research, said the transplant – carried out in September 2016 when the recipient was 32 – shows the technique is feasible and could offer women with uterine infertility access to a larger pool of potential donors.

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. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.. Pixabay

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it.

“The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population,” Ejzenberg said in a statement about the results.

She added, however, that the outcomes and effects of womb donations from live and deceased donors have yet to be compared, and said the technique could still be refined and optimised.

The first baby born after a live donor womb transplant was in Sweden in 2013. Scientists have so far reported a total of 39 procedures of this kind, resulting in 11 live births.

Experts estimate that infertility affects around 10 to 15 percent of couples of reproductive age worldwide. Of this group, around one in 500 women have uterine problems.

Before uterus transplants became possible, the only options to have a child were adoption or surrogacy.

Infants, baby, WOmb
The case, published in The Lancet medical journal, involved connecting veins from the donor uterus with the recipient’s veins. Pixabay

In the Brazilian case, the recipient had been born without a uterus due to a condition called Mayer-Rokitansky-Küster-Hauser syndrome. The donor was 45 and died of a stroke.

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Five months after the transplant, Ejzenberg’s team wrote, the uterus showed no signs of rejection, ultrasound scans were normal, and the recipient was having regular menstruation. The woman’s previously fertilized and frozen eggs were implanted after seven months and 10 days later she was confirmed pregnant.

At seven months and 20 days – when the case study report was submitted to The Lancet – the baby girl was continuing to breastfeed and weighed 7.2 kg (16 lb). (VOA)

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Study Claims, There Should Be Treatment Options Given for Miscarriage

Miscarriage is the most common complication of pregnancy and affects an estimated one in four pregnancies. 

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Miscarriage is the most common complication of pregnancy and affects an estimated one in four pregnancies. Pixabay

Though miscarriage is a traumatic experience for both parents, resulting in feelings of loss and grief that in some cases can lead to anxiety and depression, women experiencing miscarriage should be offered a choice in the treatment they receive, suggests a study.

Miscarriage is the most common complication of pregnancy and affects an estimated one in four pregnancies.

Although guidelines recommend trying to resolve an unsuccessful pregnancy naturally, the new analysis shows that this is only successful in 70 per cent of cases, and potentially comes with complications that are rarely communicated to patients.

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Some women are more keen on having a quick surgical intervention so that they can resume their lifestyle immediately, some are very keen to avoid surgery and prefer to go with a tablet, and others want to take a more natural approach,” Wattar added. Pixabay

The study from the University of Warwick and Queen Mary University of London, demonstrates little to no difference in medical effectiveness in resolving an unsuccessful pregnancy between medical and surgical options.

Thus, the team recommend the doctors to offer women a choice of treatment options for miscarriage to enable them to make an informed decision that takes account of potential uncomfortable side effects, long waiting times and extended periods of recovery.

“What we have to do is provide women with evidence about the benefits and effectiveness of each treatment option and potential side effects so that they can choose what they feel most comfortable with,” said lead author Bassel Wattar from Warwick Medical School.

“Some women are more keen on having a quick surgical intervention so that they can resume their lifestyle immediately, some are very keen to avoid surgery and prefer to go with a tablet, and others want to take a more natural approach,” Wattar added.

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Miscarriage is the most common complication of pregnancy and affects an estimated one in four pregnancies. Pixabay

For the results, published in the journal Human Reproduction Update, the team reviewed 46 trials involving over 9,000 women who experienced spontaneous loss of pregnancy (miscarriage) before 14 weeks gestation.
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During a miscarriage, the body will aim to resolve the unsuccessful pregnancy naturally but conservative treatment can be painful with increased bleeding, increased likelihood of hospital admission, reduced quality of treatment and reduced satisfaction.

However, surgery which include electric vacuum aspiration, and medical treatment with a tablet were found to have similar effectiveness in treating miscarriage as conservative treatment. (IANS)