Wednesday November 21, 2018

Gut Microbiota Can Help Identify Liver Cancer: Researchers

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

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How gut microbiota can aid in early diagnosis of liver cancer.
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Chinese researchers have identified gut microbiota as a new biomarker of liver cancer, that can help in early diagnosis as well as treatment of the condition.

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the third leading cause of cancer-related death worldwide.

Due to the absence of specific symptoms in early stages and the lack of diagnostic markers, most patients with HCC are often diagnosed in an advanced stage.

Liver Cancer
AFP is a plasma protein that is produced in abundance by the liver cells. Pixabay

Researchers from China’s Zhejiang University, and Zhengzhou University, found that the microbial diversity in patients with cirrhosis was significantly lower than that in healthy people, but it increased when cirrhosis develops into cancer, the Xinhua reported.

Human gut microbiota has been considered the most important micro-ecosystem living with the body, containing tens of trillions of microorganisms, including at least 1,000 species of bacteria with more than 3 million genes.

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

Liver Cancer
A high-magnification image from a 2012 glioblastoma case is seen as an example in this College of American Pathologists image released from Northfield. VOA

For the study, appearing in the journal Gut, the team collected 486 fecal samples from across the country.

Also Read: Deaths Due to Cancer Increases to More Than 18 Mn Every Year: WHO

About 12 bacteria genera decreased and six increased in patients with early cancer compared with healthy people.

According to researchers, more data and further studies are needed to confirm the validity and reliability of the model. (IANS)

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Growth Hormone Deficiency May Also Hit Healthy Children

Since he started getting these injections two years ago, Spencer has grown about 15 centimeters.

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FILE - UNICEF staff measure a girl's height to see if she is stunted in a village health clinic of South Hamgyong province, North Korea. VOA

Most healthy children between the ages of four and 10 grow about five centimeters (two inches) a year. So, one family knew something was wrong when their son fit into the same clothes, season after season. Doctors were able to get him growing once again after testing for a growth hormone.

Eleven year-old Spencer Baehman is passionate about baseball.

“My goal is to play college baseball,” Spencer said.

There was only one problem. Spencer was the shortest player on his team. It didn’t stop him from playing, but the height difference was noticeable. And it made Spencer feel different.

“I want to be as tall as these kids,” Spencer said.

At first, Spencer’s parents thought their son was just small, but gradually, they suspected something was wrong. His mom, Stephanie Baehman, became worried.

“It really set in one year coming out of winter into spring when he got out his cleats for spring baseball and he put them on, and they fit. And they never should have fit. Those were from the spring prior,” Baehman said.

Spencer’s parents set up an appointment with Dr. Bert Bachrach, the chief of pediatric endocrinology at University of Missouri Health Care. Nurses measured Spencer’s height.

After careful testing, Dr. Bachrach determined a growth hormone deficiency was causing Spencer’s growth failure. Hormones are basically chemicals that send messages from one cell to another.

“Growth hormone just doesn’t affect your growth, it affects your muscle mass and fat distribution, so that affects your cholesterol, that affects you overall, it also affects your overall sense of wellbeing,” Bachrach said.

Young Kids learning
Young Kids learning. pixabay

Growth hormone insufficiency is a disorder involving the pituitary gland which is a small, pea-sized gland located at the base of the brain. It’s this gland that produces human growth hormone, among others.

Also Read: Poor Aerobic Fitness Increases Risk of Diabetes in Kids

Every day, Spencer’s mother gives him a daily hormone injection. Since he started getting these injections two years ago, Spencer has grown about 15 centimeters (six inches). But just in case he doesn’t grow tall, he has a reminder written in each of his baseball caps.

“It says HDMH, which means height doesn’t measure heart,” Spencer read.

And heart is something Spencer has plenty of. (VOA)