Wednesday November 20, 2019

High Level Of Insulin in Infants May Rise Chances Of Brain Damage

"One of the problems facing clinicians is that it's really difficult to predict which babies will have problems after surgical treatment," said Karen Cosgrove, from the varsity.

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Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells. Pixabay

Babies born with abnormally high levels of insulin are at the risk of suffering permanent brain damage and life-long disability, finds a study that showed it’s possible to predict when and how the condition may affect the child in the long-term.

The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry.

So far, scientists understood that there were two main subtypes of the disease known as diffuse — affects the entire pancreas — and focal — affects just one area of the organ.

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In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

The new study, led by a team from the University of Manchester in the UK, showed that focal CHI can be further categorised into two types — spreading focal lesions and isolated focal lesions.

Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells.

For the study, published in the Frontiers in Endocrinology journal, the team investigated the cases of 25 infants with focal CHI to see how the two types of lesions influenced their long-term outcomes.

They found babies with spreading focal lesions suffered more severely from the disease and were diagnosed earlier. These infants were more likely to suffer brain damage, which permanently affected their development, learning and behaviour.

insulin
The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

These data help to explain why newborn babies diagnosed with the same disease may go on to have very different outcomes and could influence the way clinicians choose to manage each new case of CHI.

Also  Read:‘Model Chinese’ Parents Who Spent Their Careers As Loyal Civil Servants, Get Free of Uyghur Exile After Daughter’s Interview

“One of the problems facing clinicians is that it’s really difficult to predict which babies will have problems after surgical treatment,” said Karen Cosgrove, from the varsity.

“Our data gives some important clues that will help clinicians to know how much extra care each baby is likely to need,” Cosgrove said. (IANS)

 

 

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Here’s How Healthy Diet Reduces Risk Of Hearing Loss

Study has found that healthy diet can lower the risk of hearing loss

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Healthy diet
Eating a healthy diet can lower the risk of hearing loss. Pixabay

Researchers have found that eating a healthy diet may reduce the risk of acquired hearing loss.

Using longitudinal data collected in the Nurses’ Health Study II Conservation of Hearing Study (CHEARS), researchers from Brigham and Women’s Hospital in US, examined three-year changes in hearing sensitivities and found that women whose eating patterns adhered more closely to commonly recommended healthful dietary patterns have substantially lowered risk of decline in hearing sensitivity.

“A common perception is that hearing loss is an inevitable part of the aging process. However, our research focuses on identifying potentially modifiable risk factors – that is, things that we can change in our diet and lifestyle to prevent hearing loss or delay its progression,” said lead author Sharon Curhan.

“The benefits of adherence to healthful dietary patterns have been associated with numerous positive health outcomes and eating a healthy diet may also help reduce the risk of hearing loss,” Curhan added.

Previous studies have suggested that higher intake of specific nutrients and certain food, such as the carotenoids beta-carotene and beta-cryptoxanthin (found in squash, carrots, oranges and other fruits and vegetables) were associated with lower risk of self-reported hearing loss.

Healthy diet for hearing
Hearing Loss is believed to be the part of the aging process but a healthy diet can lower the risk of hearing loss. Pixabay

For the study published in the American Journal of Epidemiology, the researchers established 19 geographically diverse testing sites across the US and trained teams of licensed audiologists to follow standardised CHEARS methods.

The audiologists measured changes in pure-tone hearing thresholds, the lowest volume that a pitch can be detected by the participant in a given ear, over the course of three years.

An audiologist presented tones of different frequencies (0.5, 1 and 2 kHz as low-frequencies; at 3 kHz and 4 kHz as mid-frequencies; and at 6 kHz and 8 kHz as higher frequencies) at variable “loudness” levels and participants were asked to indicate when they could just barely hear the tone.

Using over 20 years of dietary intake information that was collected every four years beginning in 1991, the researchers investigated how closely participants’ long-term diets resembled some well-established and currently recommended dietary patterns, such as the DASH diet, the Mediterranean diet, and Alternate Healthy Index-2010 (AHEI-2010).

Greater adherence to these dietary patterns has been associated with a number of important health outcomes, including lower risk of heart disease, hypertension, diabetes, stroke and death as well as healthy aging.

The team found that the odds of a decline in mid-frequency hearing sensitivities were almost 30 per cent lower among those whose diets most closely resembled these healthful dietary patterns, compared with women whose diets least resembled the healthy diet. In the higher frequencies, the odds were up to 25 per cent lower.

Also Read- Mutations in Genes Associated with Heart Disease: Study

“The association between diet and hearing sensitivity decline encompassed frequencies that are critical for speech understanding,” said Curhan.

“We were surprised that so many women demonstrated hearing decline over such a relatively short period of time,” Curhan added. (IANS)