Thursday July 18, 2019

High Level Of Insulin in Infants May Rise Chances Of Brain Damage

"One of the problems facing clinicians is that it's really difficult to predict which babies will have problems after surgical treatment," said Karen Cosgrove, from the varsity.

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Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells. Pixabay

Babies born with abnormally high levels of insulin are at the risk of suffering permanent brain damage and life-long disability, finds a study that showed it’s possible to predict when and how the condition may affect the child in the long-term.

The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry.

So far, scientists understood that there were two main subtypes of the disease known as diffuse — affects the entire pancreas — and focal — affects just one area of the organ.

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In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

The new study, led by a team from the University of Manchester in the UK, showed that focal CHI can be further categorised into two types — spreading focal lesions and isolated focal lesions.

Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells.

For the study, published in the Frontiers in Endocrinology journal, the team investigated the cases of 25 infants with focal CHI to see how the two types of lesions influenced their long-term outcomes.

They found babies with spreading focal lesions suffered more severely from the disease and were diagnosed earlier. These infants were more likely to suffer brain damage, which permanently affected their development, learning and behaviour.

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The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

These data help to explain why newborn babies diagnosed with the same disease may go on to have very different outcomes and could influence the way clinicians choose to manage each new case of CHI.

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“One of the problems facing clinicians is that it’s really difficult to predict which babies will have problems after surgical treatment,” said Karen Cosgrove, from the varsity.

“Our data gives some important clues that will help clinicians to know how much extra care each baby is likely to need,” Cosgrove said. (IANS)

 

 

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OPPO to Establish New Research and Development Centre in China to Boost its R&D Capabilities

The smartphone player will spend 10 billion Renminbi (around $1.46 billion) on R&D this year

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The new facilities, along with the company's existing R&D centres, will form a robust research engine that powers its innovation for the emerging era of intelligent connectivity. Pixabay

Chinese handset maker OPPO on Friday announced it will establish a new research and development centre in China’s Chang’an Town, Dongguan, Guangdong Province as it aims to boost its R&D capabilities.

The new facilities, along with the company’s existing R&D centres, will form a robust research engine that powers its innovation for the emerging era of intelligent connectivity.

The smartphone player will spend 10 billion Renminbi (around $1.46 billion) on R&D this year.

“We are very pleased to officially break ground on OPPO’s new Chang’an R&D centre. It will play a strategic role in OPPO’s R&D endeavours, further enhancing the core technological capabilities of the company and accelerating the implementation of our R&D strategy and objectives,” Eric Zhu, Vice President, OPPO, said in a statement.

OPPO, Research, Development
Chinese handset maker OPPO on Friday announced it will establish a new research and development centre in China’s Chang’an Town. Pixabay

“The project will be built to the highest industrial standards and we will spare no effort in making the new R&D centre a masterpiece initiative in the Guangzhou-Shenzhen Science and Technology Innovation Corridor, helping to bolster the development of the Guangdong-Hong Kong-Macao Greater Bay Area.”

According to the handset maker, OPPO’s Chang’an R&D centre is one of Dongguan’s major initiatives to drive the development of the Guangdong-Hong Kong-Macao Greater Bay Area, and is expected to house 5,000 R&D personnel upon completion.

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As a global R&D engine for the company, the R&D centre will be responsible for the R&D, design and testing of a range of smart devices, including smartphones and IoT products.(IANS)