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Most women are aware of reproductive facts and something called a biological clock ticking away. This comes into prominence especially when couples plan their pregnancy. One should keep in mind that fertility is age-related for both men and women and this understanding is pivotal because it helps in conceiving, the baby’s health depends on it and one can make informed choices during pregnancy.
How age affects a women’s fertility as compared to men?
Fertility with age has a different effect on men and women. A woman is born with a certain number of eggs that only get depleted over a period of time, and after some time she can’t produce any more eggs. But in the case of a man, he can produce sperms his entire life. Therefore, it signifies the women’s pregnancy health window is short as compared to a man’s, who can even father a child in their 60s and 70s. So, let’s have a look at fertility across different age groups:
Fertility in their 20s:
According to the experts, this is the perfect age group for a woman to have a healthy pregnancy. This is the age when women are most fertile. The difference between infertility in their early 20s and late 20s is almost negligible.
Some of the great advantages of pregnancy during this age group are:
* As your eggs have lesser odds of carrying genetic abnormalities, the chances of your child having any genetic disorders such as Down Syndrome, Thalassemia, etc. is minimal
* The risk of miscarriage lays only 10 percent
* Less likely that you will have a premature baby or baby with low birth weight
* Even the mother has a lower risk of any health complications like gestational diabetes or hypertension.
The disadvantages of this phase are:
* In a first pregnancy, the risk of pre-eclampsia, a pregnancy complication, becomes higher
* If you have PCOD or uterine fibroids or any underlying medical condition, achieving a pregnancy is complicated.
* When it comes to male fertility, they don’t have to worry at all. If at all infertility has been diagnosed in a man, then it’s all because of his lifestyle choices that lead to obesity, hypertension, contraction of any sexually transmitted infection, and diabetes. This can be reversed in the case of men by altering lifestyle choices. Sexually Transmitted Infections in men affect the motility and concentration of sperms.
Fertility in their 30s:
If a woman wants to conceive in this phase of her life, then the chances of expecting are between 15 and 20 percent each month provided they don’t have any underlying health conditions. A study has confirmed that women in their 30s have 30 percent chances of conceiving on their first try. But, fertility tends to decline when a woman reaches 35 because of the decreased quality and quantity of the eggs. Even the chances of conceiving naturally after 35 are also minimal. The increased level of the follicle-stimulating hormone in a female body makes her more prone to having twins or triplets.
The risks of conceiving in the 30s are:
* Higher C-section rates
* Higher chances of genetic issues in the newborn
* Increased rates of miscarriages and stillbirths
* Elevated risks of ectopic pregnancy
Fertility in your 40s and beyond:
In the case of a woman, it’s not impossible to conceive in this age but one should take notice of the fact that during each ovulatory cycle, the pregnancy rate dips to 5 percent between 40 and 44, whereas beyond 45 it gets reduced to 1 percent. According to the Center for Disease Control, half of the women across the globe undergo fertility issues in their 40s. The risk factors of conceiving remain the same as it is in their 30s. Since there are risk factors involved, there is no guarantee that a female can conceive for sure. Even a man’s fertility also declines in this age group as the sperm count and semen volume also decrease. But, one should not give up hope and consult a fertility expert at the right time.
Ultimately, the perfect time to get pregnant is when you feel it’s the right time for you. It’s completely fine if want to feel more confident in your career and finances to start building your family. If you do choose to wait, do consult with your doctor or a fertility specialist to make sure no health issues will come as surprise once you’re ready. The fertility expert will not only help you know your ovarian reserve but can also suggest ways and means preserve your fertility till you are ready to become a mother. (IANS/JC)
The US researchers have discovered a class of immune cells that plays a role in miscarriage, which affects about a quarter of pregnancies.
Researchers at the University of California-San Francisco found that the recently discovered subset of cells known as extrathymic Aire-expressing cells in the immune system may prevent the mother's immune system from attacking the placenta and fetus.
The researchers showed that pregnant mice who did not have this subset of cells were twice as likely to miscarry, and in many of these pregnancies fetal growth was severely restricted.
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"When you're pregnant, the immune system is seeing the placenta for the first time in decades -- not since the mother made a placenta when she herself was a fetus," said Eva Gillis-Buck, from UCSF.
"Our research suggests that this subset of immune cells is carrying out a sort of 'secondary education' -- sometimes many years after the better-known population of the educator cells have carried out the primary education in the thymus -- teaching T cells not to attack the fetus, the placenta and other tissues involved in pregnancy," she added. The findings are published in the journal Science Immunology.
The immune system has to be educated not to attack one's own tissues and organs to prevent autoimmune disease. But pregnancy presents a unique challenge since the fetus expresses proteins found in the placenta as well as proteins whose genetics are distinct from the mother.
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"It was a conceptual leap to link Aire-expressing cells, which are critical for preventing autoimmune disease, to pregnancy," said Tippi Mackenzie, Professor of Surgery at UCSF's Center for Maternal Foetal Precision Medicine.
In the thymus, Aire-expressing cells begin interacting with other immune cells very early in life to teach them what not to attack. The thymus begins to shrink and is nearly gone by adulthood, by which time most immune cells have been educated. But as the thymus shrinks, the population of eTACs in lymph nodes and the spleen expands, the researchers explained.
The study suggests a healthy pregnancy may depend on having these cells around, they added. (IANS/KB)
The tiny emojis being shared on billions of devices worldwide can play a major role in digital communication, with most people saying that emoji compels them to feel more empathy towards others, according to an Adobe report.
Adobe's global emoji study found that emoji even helps people overcome language barriers and form connections that would otherwise be difficult to do.
"We were surprised and delighted by the discoveries made in the survey, most notably how enthusiastic respondents were for emoji as a means to express themselves," the company said in a statement.
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Emojis sometimes get criticized for being overly saccharine, but this sweetness is key when it comes to diffusing some of the heaviness of online communication.
"Many of the emoji are focused on positive emotions, so it's easy to insert them into our conversations and lighten the mood," the Adobe study said.
It's not surprising that over half of those surveyed feel more comfortable using emojis than talking on the phone or in person.
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This applies to less intense situations too. Dating, for example, can be tricky — especially when it's online or via digital apps, as it often is now.
The study also found that emoji even helps people overcome language barriers and form connections that would otherwise be difficult to do.
In celebration of World Emoji Day on Saturday, Adobe's '2021 Global Emoji Trend Report' surveyed 7,000 people in the US, the UK, Germany, France, Japan, Australia, and South Korea. (IANS/KB)
Following the grand Richard Branson show where he carried Andhra Pradesh-born Sirisha Bandla and fellow space travelers on his shoulders after successfully flying to the edge of space, it is time for Amazon Founder Jeff Bezos to applaud Sanjal Gavande, one of the key engineers who designed the New Shephard rocket set to take Bezos and the crew to space on July 20.
Billionaire Bezos is set to fly to the edge of space aboard what is touted as the world's first unpiloted suborbital flight. Born in Kalyan, Maharashtra, Gavande is a systems engineer at Blue Origin who always dreamt of designing aerospace rockets.
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After completing Bachelor's in mechanical engineering from the University of Mumbai, she flew to the US in 2011 to pursue a Master's in mechanical engineering from the Michigan Technological University. She also applied for an engineering job at the US space agency NASA but finally landed her dream job at Blue Origin
Sirisha flew to the US in 2011 to pursue a Master's in mechanical engineering from the Michigan Technological University.IANS
Bezos, his brother Mark, aviation pioneer Mary Wallace 'Wally' Funk, and other passengers are set to liftoff from west Texas and travel just beyond the edge of space on July 20. Blue Origin announced this week that Oliver Daemen, an 18-year-old high school graduate from the Netherlands, would join the crew.
Oliver is the son of millionaire Joe Daemen, Founder, and CEO of the Dutch investment company Somerset Capital Partners. Blue Origin, however, did not reveal how much Daemen paid for his son's trip to space. Bezos chose July 20 as the launch date to honor the 52nd anniversary of the Apollo 11 moon landing.
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The launch site for Blue Origin's first human flight will be in a remote location north of Van Horn, Texas, from where the firm had launched New Shepard for previous flights. Blue Origin has received final approval from the Federal Aviation Administration (FAA) to carry humans on the New Shepard rocket into space.
On July 12, Bandla touched the edge of space with three others, including Virgin Galactic's billionaire CEO Richard Branson. Bandla vaulted into space onboard VSS Unity 22. After the successful spaceflight, Branson carried the Indian-American on his shoulders while celebrating their flight to space, at Spaceport America in New Mexico. (IANS/KB)