Thursday November 23, 2017

India and Africa are the next Destination for Malaria Parasites: Study

Sri Lanka is supposed to be malaria-free and it too should start worrying.

0
111
Malaria, Wikimedia

Bengaluru, Feb 3, 2017: Detection of malaria parasites resistant to the front line artemisinin (ART) combination therapy in some south Asian countries should worry India, Govindarajan Padmanabhan a top biochemist and malaria researcher at the Indian Institute of Science here has warned.

NewsGram brings to you latest new stories in India.

Africa and India can as well be the superbug’s next destination and, if it spreads, this will pose a disaster, Padmanabhan told this correspondent, adding: Sri Lanka is supposed to be malaria-free and it too should start worrying.

The British journal Lancet Infectious Diseases had recently reported that P. falciparum malaria parasites resistant to both ART and its widely used partner drug, piperaquine, are now spreading quickly throughout western Cambodia, southern Laos and northeastern Thailand.

The study, by researchers at Mahidol University in Thailand and Oxford University, warned that the consequences of resistance spreading further into India and Africa could be grave if drug resistance is not tackled from a global public health emergency perspective.

Artemisinin, also known as qinghaosu — extracted from the Artemisia annua plant — is a powerful and perhaps the only really effective anti-malarial at present. But because ART has a very short half-life, the World Health Organisation had insisted that it should only be used as a combination with another long-acting anti-malarial.

Thus came the combination therapies: ART-lumefantrine, ART-meflaquine, ART- Sulfadoxine/pyrimethamine (ART-SP) and Dihydroartemisinin-piperaquine (DHA-PPQ).

Padmanabhan said that over the years, the malaria parasite had developed resistance even to many combination therapies, except DHA-PPQ, that had remained very effective.

Now the recent report of the parasite’s resistance to this combination also is really worrisome.

The spread of resistance will be a huge challenge to health workers, he said. This challenge will always go on and that is why I really want to try ART-curcumin combination, which may be an answer to resistance development, the scientist noted.

Go to NewsGram and check out news related to political current issues.

Curcumin, is the compound that gives turmeric (haldi) its trademark bright yellow colour.

The ART-curcumin combination is unique, with potential advantages over the known combination therapies, Padmanabhan said. In trials carried out on mice, three oral doses of curcumin following a single injection of artemisinin to infected mice were able to ensure almost 100 per cent survival of the animals.

In addition to having a direct killing effect as an anti-malarial, curcumin is also able to prime the immune system against malaria parasites in mice rendering the combination to act like a therapeutic vaccine, Padmanabhan said.

Look for latest news from India in NewsGram.

Thus, this combination has unique potential to prevent parasite recrudescence and relapse. Besides it is cheap and no resistance against it is known since it is a dietary supplement.

Padmanaban and his team are hoping to start human trials of an artemisinin-curcumin combination therapy in both simple malaria cases and in the treatment of the deadly cerebral malaria. He said regulatory clearances are awaited.

(IANS)

Next Story

Dalai Lama says that India and China have great potential

The spiritual leader feels that both the countries are doing compassionate works

0
34
Dalai Lama talks about India and China
Tibetan spiritual leader Dalai says that India and China can work together. VOA

New Delhi, Nov 19

Tibetan spiritual leader the Dalai Lama on Sunday said India and China have “great potential” and they could work together at a “practical level”.

“I think, a great potential… India and China combined are doing more compassionate work… At a practical level also. Imagine two billion people working together,” he told reporters here after inaugurating Smile Foundation’s initiative, The World of Children.

The spiritual leader, who has lived in India in self-imposed exile since 1959, said neither country had the “ability to destroy the other”.

“Whether you like it or not, you have to live side by side,” he said.

Underlining the ancient spiritual connection between the two countries, he said Chinese Buddhist Hsuan Tsang visited Nalanda (now in Bihar) and brought Nalanda Buddhist traditions to China.

“All thinkers of Nalanda are Indian. So Nalanda’s tradition is India’s tradition,” he said.

The Nalanda traditions had turned Tibetans, who were warriors, into more compassionate, peaceful and non-violent nation, he said.

“So sometimes in Delhi, teasing my Indian friend, (I say) if Tibet still remained in the previous way of life, like Mongols, Chinese invasion may not have taken place,” the Dalai Lama said in a lighter vein.

He said nobody in the world wanted violence but it was happening “because our minds are dominated by destructive emotions due to short-sightedness”.

“Nobody wants problems. Yet, many problems are our own creation.”

The Dalai Lama said the existing modern education was oriented to material values. India can take lead in improving the education system by combining modern education with ancient knowledge, he said. (IANS)

Next Story

Manushi Chhillar from India Wins the Miss World 2017 Title

India's Manushi Chillar won the coveted Miss World 2017 pageant here, 16 years after Priyanka Chopra won the title in 2000.

0
101
Miss World
Manushi Chhillar has been crowned as Miss World 2017. Instagram #ManushiChhillar

China, November 19: India’s Manushi Chhillar won the coveted Miss World 2017 pageant, 16 years after Priyanka Chopra won the title in 2000.

Chhillar competed against 108 contestants from various countries at a glittering event held at Sanya City Arena here.

Miss World 2016 winner Puerto Rico’s Stephanie Del Valle gave away the coveted crown to the winner.

Chhillar, who is from Haryana, had earlier this year won the Femina Miss India 2017.

Miss world
Anti Ageing was the official skin care expert for Manushi Chhillar at the Miss World 2017 pageant. Instagram #ManushiChhillar

India, England, France, Kenya and Mexico grabbed the top five spots at the peagant.

Manushi, born to doctor parents, studied in St. Thomas School in New Delhi and Bhagat Phool Singh Government Medical College for Women in Sonepat.

Her entire family including brother and sister were present and they looked excited watching Manushi grabbing top five spot.

As many as 108 beauty queens from different parts of the world participated in the prestigious pageant. (IANS)

Next Story

The major Challenge is to make the Youth of the Country Entrepreneurial and not Job Seekers : Venkaiah Naidu

"The challenge for us is to make the youth entrepreneurial, and not become job seekers," Venkaiah Naidu said pointing to the NDA government's various initiatives.

0
15
Venkaiah Naidu
Venkaiah Naidu. Wikimedia Commons
  • At a time of tepid job growth and continuing income disparities, the major challenge is to make the youth of the country entrepreneurial and not job seekers, Vice President  Venkaiah Naidu said on Thursday.

“Disparities continue to remain in India and so there is a need for inclusive growth… there is the need to take care of the suppressed, oppressed and depressed,” Venkaiah Naidu said at the Bharatiya Yuva Shakti Trust’s (BYST) silver jubilee celebrations here with Britain’s Prince Charles as the chief guest.

“The challenge for us is to make the youth entrepreneurial, and not become job seekers,” Venkaiah Naidu said pointing to the NDA government’s various initiatives to encourage youth enterprises like Startup India, Standup India and the Mudra financing scheme for underprivileged sections.

Modelled on Prince Charles’ Trust for business startups, BYST, founded by Lakshmi Venkatesan, daughter of former President R. Venkatraman, is engaged in building rural entrepreneurship — “grampreneurs” — as also enterprise among under-privileged sections, which includes business mentoring. The current BYST chairman is Bajaj Group chief, Rahul Bajaj.

“Without mentoring, it would be very difficult to set up startups, with all the business, marketing and other vital issues involved in the first two-three years,” Prince Charles said in his address at the International Mentoring Summit organized by BYST to mark its 25 years.

“What amazes me are the sheer number of jobs these young entrepreneurs had created. The aim of such a project should be to create a virtual cycle of creating entrepreneurs who can then invest in the future of business,” Charles said referring to his trust.

BYST was officially launched in 1992 by Prince Charles and expanded its operations to six major regions of India.

Out of these six regions, four — Delhi, Chennai, Pune and Hyderabad — run the urban programme while two regions — Haryana and Maharashtra — run the rural programme.(IANS)