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Indian-American scientist uses sound waves to control brain cells

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photo credit: www.biosciencetechnology.com

Washington: Indian-American researcher Sreekanth Chalasani, from Salk Institute for Biological Studies in California has developed a new way to selectively activate brain, heart, muscle and other cells using ultrasonic sound waves.

photo credit: www.ndtv.com
photo credit: www.ndtv.com

Dubbed as sonogenetics, the new technique has some similarities to the burgeoning use of light to activate brain cells in order to better understand the brain.

“Light-based techniques are great for some uses. But this is a new, additional tool to manipulate neurons and other cells in the body,” informed Sreekanth Chalasani, assistant professor in Salk’s molecular neurobiology laboratory.

The new method – which uses the same type of waves used in medical sonograms – may have advantages over the light-based approach – known as optogenetics – particularly when it comes to adapting the technology to human therapeutics.

In optogenetics, researchers add light-sensitive channel proteins to neurons they wish to study.

By shining a focused laser on the cells, they can selectively open these channels, either activating or silencing the target neurons.

Chalasani and his group decided to see if they could develop an approach that instead relied on ultrasound waves for the activation.

“In contrast to light, low-frequency ultrasound can travel through the body without any scattering,” he noted.

“This could be a big advantage when you want to stimulate a region deep in the brain without affecting other regions,” adds Stuart Ibsen, post-doctoral fellow in the Chalasani lab.

“The real prize will be to see whether this could work in a mammalian brain,” Chalasani pointed out.

His group has already begun testing the approach in mice. “When we make the leap into therapies for humans, I think we have a better shot with noninvasive sonogenetics approaches than with optogenetics,” he emphasised in a paper appeared in the journal Nature Communications.

Chalasani obtained his PhD from University of Pennsylvania. He then did his post-doctoral research in the laboratory of Dr Cori Bargmann at the Rockefeller University in New York.

(IANS)

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Microsoft to Implement California’s Digital Privacy Law Throughout the US

The European Union last year rolled out new privacy regulations for its citizens called the GDPR, but the US doesn't have a similar law

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FILE - A sign for Microsoft is seen on a building in Cambridge, Massachusetts, March 18, 2017. VOA

Microsoft has announced to implement California’s digital privacy law, that comes into effect from January 1, 2020, throughout the US.

In a blog post, the tech giant said the California Consumer Privacy Act (CCPA) marks an important step towards providing people with more robust control over their data in the US.

“It also shows that we can make progress to strengthen privacy protections in this country at the state level even when Congress can’t or won’t act,” Julie Brill, Microsoft’s chief privacy officer, said on Monday.

The CCPA allows people to request that data be deleted and gives them the opportunity to opt out of having their information sold to a third party.

In 2018, Microsoft voluntarily extended the core data privacy rights included in the European Union’s General Data Protection Regulation (GDPR) to customers around the world, not just to those in the EU who are covered by the regulation.

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FILE – Microsoft Corp. signage is seen outside the Microsoft Visitor Center in Redmond, Washington, July 3, 2014. VOA

“Similarly, we will extend CCPA’s core rights for people to control their data to all our customers in the US,” it said.

More than 25 million people around the world, including over 10 million people in the US, have used Microsoft’s privacy dashboard to understand and control their personal data.

Also Read: Apple Mulling to Release its First AR Headset by the Year 2022

Under CCPA, companies must be transparent about data collection and use, and provide people with the option to prevent their personal information from being sold.

“Microsoft will continue to monitor those changes, and make the adjustments needed to provide effective transparency and control under CCPA to all people in the US,” Brill said.

The European Union last year rolled out new privacy regulations for its citizens called the GDPR, but the US doesn’t have a similar law. (IANS)