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Know why Sound of Chewing Food and Pen Clicking can cause Irritation!

The findings showed that the brains of people with such condition are known as 'misophonia' or 'hatred of trigger sounds'

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London, February 3, 2017: Ever wondered why the sound of people chewing food, breathing off, a pen clicking repeatedly cause irritation? It may be because of an abnormality in the emotional control mechanism which causes the brain to go into overdrive on hearing such trigger sounds, say researchers led by one of Indian-origin.

The findings showed that the brains of people with such condition — known as misophonia or hatred of trigger sounds — showed a physical difference in the frontal lobe between the cerebral hemispheres — with higher myelination in the grey matter of ventromedial prefrontal cortex (vmPFC).

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“For many people with misophonia…for the first time we have demonstrated a difference in brain structure and function in sufferers,” said Sukhbinder Kumar at Newcastle University in Britain.

Further, the study, published in the journal Current Biology, also showed abnormal connections between this frontal-lobe area and an area called the anterior insular cortex (AIC) — known to be involved in processing emotions and integrating signals both from the body and outside world.

In misophonic participants, the trigger sounds increased activity in both brain areas, while in normal participants, the increase was seen only in the AIC, not in the frontal area.

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This reflects an abnormality of a control mechanism between the frontal lobe and AIC, the researchers said.

“We now have evidence to establish the basis for the disorder through the differences in brain control mechanism in misophonia. This will suggest therapeutic manipulations and encourage a search for similar mechanisms in other conditions associated with abnormal emotional reactions,” added Tim Griffiths, professor at Newcastle University.

The trigger sound was also found to evoke a heightened physiological response with increased heart rate and sweating in people with misophonia, the researchers noted. (IANS)

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Why Exercise on Empty Stomach May be Better for Your Health

This is the first study to show that feeding prior to acute exercise affects post-exercise adipose tissue gene expression

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The study analysed effects of eating versus fasting on gene expression in adipose (fat) tissue in response to exercise. Pixabay

If you have been wondering whether it is better to eat or fast before a workout, researchers now have an answer. A new study has found that exercise on empty stomach is better for your health in the long term.

The study analysed effects of eating versus fasting on gene expression in adipose (fat) tissue in response to exercise.

After eating, adipose tissue “is busy responding to the meal and a bout of exercise at this time will not stimulate the same (beneficial) changes in adipose tissue”, explained corresponding author of the study Dylan Thompson from University of Bath in Britain.

“This means that exercise in a fasted state might provoke more favourable changes in adipose tissue, and this could be beneficial for health in the long term,” Thompson added.

“We propose that feeding is likely to blunt long-term adipose tissue adaptation to regular exercise,” the researchers noted in the study published in the American Journal of Physiology — Endocrinology and Metabolism.

The study participants were a group of overweight males who walked for 60 minutes at 60 per cent maximum oxygen consumption on an empty stomach and, on another occasion, two hours after consuming a high-calorie carbohydrate-rich breakfast.

The research team took multiple blood samples after eating or fasting and after exercising.

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Representational image. Pixabay

The researchers also collected fat tissue samples immediately before and one hour after walking.

Gene expression in the adipose tissue differed significantly in the two trials.

The expression of two genes, PDK4 and HSL, increased when the men fasted and exercised and decreased when they ate before exercising.

The rise in PDK4 likely indicates that stored fat was used to fuel metabolism during exercise instead of carbohydrates from the recent meal.

Also Read: Even Light Exercises Have Health Benefits

HSL typically increases when adipose tissue uses stored energy to support increased activity, such as during exercise, Thompson said.

These results reinforce the view that “adipose tissue often faces competing challenges,” Thompson wrote.

“This is the first study to show that feeding prior to acute exercise affects post-exercise adipose tissue gene expression,” the study said. (Bollywood Country)