Wednesday, February 24, 2021
Home Life Style Health & Fitness Myeloid-Derived Suppressor Cells Ups Covid Infection Risk

Myeloid-Derived Suppressor Cells Ups Covid Infection Risk

Journal of Clinical Investigation reveals patients with severe Covid-19 have significantly high levels of a certain type of immune cells in their blood patients with severe Covid-19 have significantly elevated levels of a certain type of immune cells in their blood, called myeloid-derived suppressor cells

Researchers have found that patients with severe Covid-19 have significantly elevated levels of a certain type of immune cells in their blood, called myeloid-derived suppressor cells.

In the study, published in the Journal of Clinical Investigation, the team researched one type of immune cell, monocytic myeloid-derived suppressor cells, or M-MDSC, and their potential role in Covid-19.

Follow NewsGram on Facebook to stay updated.

“Our results help increase the understanding of what causes severe Covid-19 and is an important piece of the puzzle in understanding the connection between the early, innate immune system, which includes M-MDSC, and the later, adaptive immune system, which includes T cells,” said researcher Anna Smed Sorensen from Karolinska Institutet.

T cells are part of the immune system and play an important part in the body’s protection against viral infections such as Covid-19. M-MDSCs have been shown to increase in other inflammatory conditions, and their suppressive effect on T cell activity has been established.

Covid
The covid virus in the human blood. (Representational Image). Pixabay

The role of M-MDSC in respiratory infections, however, is largely unknown. Since low levels of T cells are a hallmark of Covid-19, it is of interest to understand the role of M-MDSCs in this disease.

The study consisted of 147 patients with mild to fatal Covid-19 who were sampled repeatedly from blood and the respiratory tract. These were then compared with patients with influenza and healthy individuals.

The results showed that patients with severe Covid-19 have significantly elevated levels of M-MDSCs in blood compared with milder cases and healthy individuals.

Covid-19 patients had fewer T cells in the blood than healthy subjects, and they showed signs of impaired function.

ALSO READ: Daler Mehndi: In 26 years music industry has gone mad

The analysis also showed that the levels of M-MDSCs early in the course of disease seemed to reflect subsequent disease severity.

“There is also a strong clinical connection, as you could potentially use the results to find new biomarkers for severe illness,” Sorensen added. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

Study: Teens May Be More Likely To Be Bullied By Their Friends

Adolescents and teens may be more likely to be bullied by their friends or friends-of-friends than peers who are not closely linked, a new...

10 Health Benefits Of Mint Leaves That One Must Know

Pudina (mint) is one of the oldest culinary herbs known to humans. It has remarkable medicinal properties and is a rich source of polyphenols....

The Job Market Still Looks Bleak In India After A Pandemic-Hit 2020

While the job market still looks bleak in India after a pandemic-hit 2020, the world's professional network LinkedIn said on Wednesday it has seen...

How The 2021 Union Budget Can Impact The Share Market In Future

By Prajakta Pingulkar Share market for beginners is a whole new territory to explore. The market speculation going throughout the year puts many new investors...

Light Intensity Physical Activity May Protect Mobility In Older Women

Light-intensity physical activity, including gardening, shopping, or a casual walk may protect mobility in older women, suggests a new study. The study indicated that...

Fat Cells May Influence How Body Reacts To Heart Failure

Limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients, say,...

An Initiative For A Drug Free India

Every year, the birth anniversary of Mahatma Gandhi is observed as National Anti-Drug Addiction Day to honor his commitment towards eradicating the menace of...

A Therapy To Rescue You From Depression And Out Of Work Load

If depression is making it more difficult for some unemployed people to land a job, one type of therapy may help, research suggests. The...

Recent Comments