Tuesday June 25, 2019

New lupus genes identified by Indian scientist

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New Delhi: 10 new lupus genes were identified by an international Indian-American team of scientists. These genes are associated with the autoimmune disease lupus-a debilitating condition where the body’s immune system becomes unbalanced and attack its own tissues.

Swapan Nath, a scientist at Oklahoma Medical Research Foundation(OMRF), and his colleagues analysed more than 17,000 human DNA samples collected from the blood of volunteers across four countries- South Korea, China, Malaysia and Japan.

Nearly 4,500 samples had confirmed cases of lupus while the rest served as healthy controls for the research.

“We know lupus has a strong genetic basis but in order to better treat the disease, we have to identify those genes,” said Nath.

From that analysis, the researchers identified 10 distinct DNA sequence variants linked to lupus.

Lupus is a chronic, autoimmune disease that can damage any part of the body. Its signs and symptoms tend to last longer than six weeks and often for many years.

This disease has been affecting nearly five million people worldwide, according to the Lupus Foundation of America.

“These findings mark a significant advance in our knowledge base for lupus genes,” said Judith James, director of OMRF’s Autoimmune Disease Institute.

“For every gene we identify, it brings us closer to uncovering the trigger for this puzzling disease. It’s good news for researchers and patients alike,” he added.

One gene known as GTF2I, showed a high likelihood of being involved in the development of lupus according to the study.

“Its genetic effect appears to be higher than previously known lupus genes discovered from Asians, and we surmise that it now may be the predominant gene involved in lupus,” Nath noted in a paper published in the journal Nature Genetics.

The understanding of the disease and development of intervention therapies for patients based on their genetic makeup was identified as the ultimate goal by Nath.(IANS)

Next Story

Measles Spread in Google’s Headquarters, Employees Discussing Ways To Protect Themselves

A select group of employees learned about the incident more than a week later, on April 13, when a company doctor emailed them about the infected the employee, the report said. 

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Later, however, the staff doctor sent a message to multiple internal groups at Google, reassuring a that they were safe while acknowledging that his communication had been "slow". Pixabay

Executives at Google’s Silicon Valley headquarters are discussing ways to protect themselves and their families from measles after one of them was found working at the office despite being infected by the highly contagious virus.

On Google’s internal forums, employees expressed shock because they were not told sooner about their sick colleague who had been spending time in its Mountain View office building — including a campus restaurant, BuzzFeed News reported on Thursday.

vaccine
Public health experts blame the uptick partially on the spread of anti-vaccine falsehoods on social media platforms, including Google’s YouTube, which, under public pressure, recently removed ads from known anti-vaccine video channels, the report said. Pixabay

The employee was present in the office on April 4.

A select group of employees learned about the incident more than a week later, on April 13, when a company doctor emailed them about the infected the employee, the report said.

Later, however, the staff doctor sent a message to multiple internal groups at Google, reassuring a that they were safe while acknowledging that his communication had been “slow”.

The reported case is part of a historic resurgence of measles in the US.

google
On Google’s internal forums, employees expressed shock because they were not told sooner about their sick colleague who had been spending time in its Mountain View office building — including a campus restaurant, BuzzFeed News reported on Thursday. Pixabay

Also Read: Apple’s Recycling Robot Is Capable of Disassembling 200 iPhones Per Hour
At least 555 people have been infected this year by the virus, which was declared eliminated in 2000, according to the Centres for Disease Control and Prevention (CDC).

Public health experts blame the uptick partially on the spread of anti-vaccine falsehoods on social media platforms, including Google’s YouTube, which, under public pressure, recently removed ads from known anti-vaccine video channels, the report said.  (IANS)