Thursday, August 6, 2020
Home Life Style Health & Fitness Novel stroke treatment repairs damaged brain tissue

Novel stroke treatment repairs damaged brain tissue

Researchers have developed a new stem-cell based treatment for stroke that reduces brain damage and accelerates the brain's natural healing tendencies

Researchers have developed a new stem-cell based treatment for stroke that reduces brain damage and accelerates the brain’s natural healing tendencies.

The treatment called AB126 was developed using extracellular vesicles (EV) — fluid-filled structures known as exosomes — which are generated from human neural stem cells.

“This is truly exciting evidence because exosomes provide a stealth-like characteristic, invisible even to the body’s own defences.

Also Read: Heart Surgery In Infants May Cause Deafness

When packaged with therapeutics, these treatments can actually change cell progression and improve functional recovery,” said Steven Stice, a professor at the University of Georgia in the US who led the research team.

Fully able to cloak itself within the bloodstream, this type of regenerative EV therapy appears to be the most promising in overcoming the limitations of many cells therapies-with the ability for exosomes to carry and deliver multiple doses-as well as the ability to store and administer treatment, the researchers said.

Human clinical trials for the treatment could begin as early as next year, the researchers added.
Human clinical trials for the treatment could begin as early as next year, the researchers added. Wikimedia Commons

Small in size, the tiny tubular shape of an exosome allows EV therapy to cross barriers that cells cannot be said the study published in the journal Translational Stroke Research.

Following the administration of AB126, the researchers used MRI scans to measure brain atrophy rates in preclinical, age-matched stroke models, which showed an approximately 35 percent decrease in the size of injury and 50 percent reduction in brain tissue loss.

Also Read: Father’s Stress Linked To Kids’ Brain Development

“Until now, we had very little evidence specific to neural exosome treatment and the ability to improve motor function. Just days after stroke, we saw better mobility, improved balance and measurable behavioural benefits in treated animal models,” Stice said.

Human clinical trials for the treatment could begin as early as next year, the researchers added. (IANS)

STAY CONNECTED

18,958FansLike
362FollowersFollow
1,782FollowersFollow

Most Popular

Vaani Kapoor Would Love to do a Biopic on Kalpana Chawla

Actress Vaani Kapoor would love to do a biopic and says it would be an absolute honour for her to play astronaut Kalpana Chawala...

Sonali Bendre: Lockdown Has Given Me No Alternative But to Become Tech Savvy

Actress Sonali Bendre Behl says the lockdown has given her no alternative but to become tech savvy. She adds that is happy to learn...

Sonu Sood: The Real Life Hero

By Venkatachari Jagannathan Sonu Sood, for the Tamil movie viewers, has until now been the actor who played the villain in "Kallazhagar" and several others....

Shoppers can Follow These Tips to Spend Worry Free Days at Malls

By N. Lothungbeni Humtsoe Malls are open and as the footfall starts to pick up, the only one who can ensure your safety on a...

Bacterial Infections May Elevate Risk of Heart Disease in Individuals With Diabetes

Researchers have found that bacterial infections may elevate the risk of coronary heart disease in individuals with type 1 diabetes. For the findings, published in...

Tips to Help you Combat Oral Health Issues

By Puja Gupta Foul breath can be a very embarrassing, putting one in an uncomfortable position. With a little bit of care, this common condition...

WhatsApp Launches ‘Search the Web’ Option to Cross-Check Forwarded Messages

WhatsApp has launched a new 'Search the Web' option that will enable users to check information shared to them via a forwarded message. The 'Search...

Early Blood Test Can Detect Baby Brain Damage Just Hours After Birth

Researchers, including one of Indian origin, have found that an early blood test could detect which babies deprived of oxygen at birth are at...

Recent Comments