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Path-breaking Clue of Treatment from HIV Infected Children who do not Develop AIDS: Scientists

Scientists at Oxford University looked at so-called pediatric non-progressors, the 5 to 10 percent of children infected with HIV who don't develop AIDS, even without treatment

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HIV-Infected Children
Kids look on in the Republican Hospital for Infectious Diseases, which specializes in treating HIV-positive children in Ust-Izhora outside St. Petersburg, Russia, Tuesday, May 30, 2006. VOA
  • Scientists at Oxford University looked at so-called pediatric non-progressors, the 5 to 10 percent of  HIV-infected children who don’t develop AIDS, even without treatment
  • Like non-human primates that harbor the simian version of HIV without becoming sick, there was very low immune activation even with high levels of the virus in their blood
  • The findings could be the first signs of people co-evolving with HIV and eventually lead to new therapies for all patients infected with the AIDS virus as per experts’ reports

Sept 30, 2016: Not everyone who is infected with HIV goes on to develop AIDS.

A tiny fraction of HIV-positive adults holds the line against AIDS by mounting a very strong immune response; but, research has found that such an approach often contributes to the development of other illnesses, such as heart disease and cancers.

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Scientists at Oxford University looked at so-called pediatric non-progressors, the 5 to 10 percent of children infected with HIV who don’t develop AIDS, even without treatment. Their study of 170 HIV-positive South African children revealed that their immune systems were behaving differently than adults’.

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Like non-human primates that harbor the simian version of HIV without becoming sick, there was very low immune activation even with high levels of the virus in their blood. Lead researcher Philip Goulder said, “(The) lack of HIV disease here seems to result from avoiding making strong immune responses against HIV.”

HIV-Infected Children
Kids look on in the Republican Hospital for Infectious Diseases, which specializes in treating HIV-positive children in Ust-Izhora outside St. Petersburg, Russia, Tuesday, May 30, 2006. VOA

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Experts said the findings, published in Science Translational Medicine, could be the first signs of people co-evolving with HIV and eventually lead to new therapies for all patients infected with the AIDS virus. (VOA)

  • Antara

    If such a treatment can be developed from the ‘infected but not with AIDS’ children, it will indeed be a path-breaking medical miracle!

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Want to Know What’s Happening Around the World Due to COVID-19? Use this App

This app to provide overview of COVID-19 pandemic globally

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COVID-19 app
Researchers have created a web application that provides an overview of the coronavirus pandemic across the globe. Pixabay

Researchers have created a web application that provides an overview of the coronavirus(COVID-19) pandemic across the globe, in a way that is more interactive than other maps and statistics.

The app titled ‘COVID-19’ is based on data from Johns Hopkins University in the US, the Danish National Serum Institute in Denmark, World Health Organisation (WHO) and the United Nations.

“We began working on the app as a pet project, to deal with our boredom and inability to physically meet up. While Skyping one day, we wondered why we couldn’t find a graph that portrayed the evolution of coronavirus cases in Denmark,” said Phillip Bredahl Mogensen from the University of Copenhagen in Denmark, one of those behind the app.

According to the study, the app provides an overview of how COVID-19 is spreading and the number of people who have both passed away and recovered.

Statistics from every country on earth are available and readily compared. For example, in only a few clicks, one can see how Spain or Italy are faring with the pandemic compared to Denmark. They also said that this is the first app that attempts to estimate suspected numbers – as opposed to reporting back confirmed positives from the test result.

COVID-19 app
According to the study, the app provides an overview of how COVID-19 is spreading and the number of people who have both passed away and recovered. Pixabay

“With the help of Danish and South Korean mortality statistics, we are able to provide an estimate of how many people were actually infected 20 days ago,” explained Bredahl Mogensen.

“For example, on March 9, there were 92 confirmed cases in Denmark. We estimate that there were actually between 1,163 and 3,615 people infected. In other words, 10 times the number of people were infected as compared to the official statistics,” he added.

Also Read- Find Out How Google is Battling Coronavirus Misinformation

The researchers used South Korean COVID-19 mortality data because the country has been dealing with the epidemic for a longer period of time and because South Korea has broader and more precise data sets than other countries.

“Even though the method is under development, and has yet to be validated, it presents an incredibly interesting estimate of the unknown extent of this virus,” the authors wrote. (IANS)