Wednesday March 20, 2019

Researchers Identified Protein Associated With Breast Cancer

In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.

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High vitamin D harming Breast Cancer, Pixabay

Researchers have found that a protein that, once deactivated, could prevent the spread of an aggressive type of breast cancer to other sites in the body, a process known as metastasis.

In their study, published in the journal Cell Reports, the researchers demonstrated that a protein, AXL, influences the occurrence of metastasis in HER2-positive cancer, an aggressive type that accounts for 20 per cent of breast cancers.

In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.

Researchers have found that a protein that, once deactivated, could prevent the spread of an aggressive type of breast cancer to other sites in the body, a process known as metastasis.
Representational Image, pixabay

The research was done on mice and with samples of tumour cells taken from cancer patients in Montreal, Canada.

In women with HER2-positive cancer, it was found that the less AXL is present, the better the survival rate.

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Previously, researchers had linked the AXL protein to another type of cancer, triple negative breast cancer, but its role in in HER2-positive cancer was not known.

“Based on this discovery, a treatment targeting AXL could reduce the risk of metastasis,” said one of the researchers Jean-Francois Cote, Professor at Universite de Montreal in Canada. (IANS)

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Beware! Sipping Hot Tea Raises Risk of Esophageal Cancer

Esophageal cancer is the sixth most common cancer in India and eighth most globally. It affects more men than women.

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Scalding water irritates the lining of the mouth and throat which can fuel tumours, scientists believe. Pixabay

Love to drink your tea piping hot? Beware, it could raise the risk of esophageal cancer, finds a study.

The study showed that risk of esophageal cancer more than doubled among those who regularly drank tea at 75 degrees Celsius

However, waiting for at least four minutes before drinking a cup of freshly boiled tea can reduce the risk of the cancer arising from the oesophagus — the food pipe that runs between the throat and the stomach.

“Many people enjoy drinking tea, coffee, or other hot beverages. However, according to our report, drinking very hot tea can increase the risk of esophageal cancer, and it is therefore advisable to wait until hot beverages cool down before drinking,” said lead author Farhad Islami of the American Cancer Society.

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The study showed that risk of esophageal cancer more than doubled among those who regularly drank tea at 75 degrees Celsius. Pixabay

The study, published in the International Journal of Cancer, involved 50,045 individuals aged 40 to 75 years.

Drinking 700 ml per day of tea or more at a higher temperature (60 degrees Celsius or higher) was associated with a 90 per cent higher risk of esophageal cancer, the researchers said.

The results could also be extended to coffee, hot chocolate or other hot beverages.

Esophageal cancer is the sixth most common cancer in India and eighth most globally. It affects more men than women.

coffee

The results could also be extended to coffee, hot chocolate or other hot beverages. pixabay

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In 2016, the World Health Organisation (WHO) had warned of the cancer risk associated with drinks above 65 degrees Celsius.

Scalding water irritates the lining of the mouth and throat which can fuel tumours, scientists believe. (IANS)