Sunday June 16, 2019

Researchers Identified Protein Associated With Breast Cancer

In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.

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High vitamin D harming Breast Cancer, Pixabay

Researchers have found that a protein that, once deactivated, could prevent the spread of an aggressive type of breast cancer to other sites in the body, a process known as metastasis.

In their study, published in the journal Cell Reports, the researchers demonstrated that a protein, AXL, influences the occurrence of metastasis in HER2-positive cancer, an aggressive type that accounts for 20 per cent of breast cancers.

In HER2-positive breast cancers, cells with high levels of AXL are more likely to detach from tumours to form metastases.

Researchers have found that a protein that, once deactivated, could prevent the spread of an aggressive type of breast cancer to other sites in the body, a process known as metastasis.
Representational Image, pixabay

The research was done on mice and with samples of tumour cells taken from cancer patients in Montreal, Canada.

In women with HER2-positive cancer, it was found that the less AXL is present, the better the survival rate.

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Previously, researchers had linked the AXL protein to another type of cancer, triple negative breast cancer, but its role in in HER2-positive cancer was not known.

“Based on this discovery, a treatment targeting AXL could reduce the risk of metastasis,” said one of the researchers Jean-Francois Cote, Professor at Universite de Montreal in Canada. (IANS)

Next Story

GRAIL Announces Significant Progress on Blood Tests to Detect Cancer

Grail's new results are from 2,300 people

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GRAIL, Blood Tests, Detect, Cancer
FILE A patient has her blood drawn at a hospital in Philadelphia to monitor her cancer treatment. VOA

A California company says its experimental blood test was able to detect many types of cancer at an early stage and gave very few false alarms in a study that included people with and without the disease.

Many companies are trying to develop early detection “liquid biopsy” tests that capture bits of DNA that cancer cells shed into blood.

GRAIL, Blood Tests, Detect, Cancer
A California company says its experimental blood test was able to detect many types of cancer at an early stage. VOA

Grail’s new results are from 2,300 people. The test detected 55% of known cancers and gave false alarms for 1%. It also accurately suggested where the cancer may be about 90% of the time.

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The company gave results in news release Friday and will report them Saturday at a conference in Chicago. They have not been published or reviewed by other scientists. (VOA)