Never miss a story

Get subscribed to our newsletter


×
CA11 may also elevate Covid-19 risk for people with diabetes. Pixabay

Scientists have decoded genes that put certain people at high chances of contracting the virus and developing severe Covid-19. Having genetic risk variants in the ABO gene might significantly increase the chances of developing Covid-19, and other genes may also increase the risk, according to researchers.

DNA is a big, complex molecule and so, genetic associations alone cannot pinpoint the exact gene responsible for Covid-19. “However, by combining Covid-19 genetic information with gene expression and proteomic datasets, we can figure out which genes are driving the relationship with Covid-19,” explained Ana Hernandez Cordero, a postdoctoral fellow with the Centre for Heart Lung Innovation, University of British Columbia.


Follow NewsGram on Facebook to stay updated.

In addition to the ABO gene, the team found that people carrying certain genetic variants for SLC6A20, ERMP1, FCER1G, and CA11 have a significantly higher risk of contracting Covid-19. “These individuals should use extreme caution during the pandemic. These genes may also prove to be good markers for disease as well as potential drug targets,” the researchers noted during a presentation at the ATS 2021 International Conference.


By harnessing the power of genomic information, we identified genes that are related to Covid-19. Pixabay

Several of the genes identified in the researchers’ analysis have already been linked with respiratory diseases. For example, ERMP1 has been linked to asthma. CA11 may also elevate Covid-19 risk for people with diabetes. The researchers combined genetic information with an examination of lung gene expression to identify genetic variants that were controlling gene expression in the lung that was responsible for Covid-19. They identified specific gene markers that share their effects on gene expression and protein levels with Covid-19 susceptibility.

ALSO READ: Mixing Covid Vaccine Doses May Raise Side Effects: Lancet

By doing this, they found that several genes responsible for the immune system’s response to Covid-19 are also involved in Covid-19 susceptibility. “By harnessing the power of genomic information, we identified genes that are related to Covid-19,” said Hernandez.

“In particular, we found that the ABO gene is a significant risk factor for Covid-19. Of particular note was the relationship between the blood group ABO and Covid-19 risk. We showed that the relationship is not just an association but causal.” These genes have been linked to severe Covid-19. “Their role in the immune response to viral infections and mounting evidence suggests that these candidates and their role in Covid-19 should be further investigated,” the team of scientists said. (IANS/JC)


Popular

IANS

Khadi is no longer a dull, drab fabric meant only for politicians' wardrobes.

Khadi is no longer a dull, drab fabric meant only for politicians' wardrobes. A fashion show organised by the Khadi Gramodyog Board as part of the Azadi Ka Amrit Mahotsav to mark the 75th year of India's Independence showcased the use of Khadi in traditional, as well as, contemporary and festive wear. From lehengas in resplendent Khadi silk to western clothes and casual wear, the models on Thursday night displayed new facts of the fabric.

Several well-known Indian designers including Ritu Beri, Farah Ansari, Rina Dhaka, Asma Husain, Aditi Rastogi and Himmat Singh showcased their designs. Gaurav Gaur directed the fashion show with clothes like lehengas, kurtis, kurta pajamas and partywear.

Lucknow's chikankari and silk artisans also participated in the event. A wedding collection in Khadi was the highlight of the show. "The show was based on the concept 'Khadi for nation, Khadi for fashion' and the fabric for all costumes was provided by Khadi Gramodyog Board," said a spokesman. (IANS/ MBI)


Keep Reading Show less
Wikimedia Commons

Pat Gelsinger, CEO - Intel

Intel saw its stock tumbling by more than 8 percent after the chipmaker said the industry-wide component shortage affected its PC chip business during the third quarter (Q3). Intel CEO Pat Gelsinger told CNBC late on Thursday that he didn't expect the semiconductor shortage to end until 2023. "We're in the worst of it now, every quarter, next year we'll get incrementally better, but they're not going to have supply-demand balance until 2023," Gelsinger was quoted as saying.


The company delivered its Q3 results with revenue up 5 percent (year-over-year) driven by strong demand in its DCG and IoTG businesses, despite the highly constrained industry-wide supply environment. "Q3 revenue was $18.1 billion slightly below our guide due to shipping and supply constraints that impacted our businesses," George S. Davis, Chief Financial Officer, said in a statement. He also announced plans to retire from Intel in May 2022. In the third quarter, the company generated $9.9 billion in cash from operations and paid dividends of $1.4 billion.

Keep Reading Show less
Photo by Nathan Dumlao on Unsplash

Micro-blogging site Twitter has announced that its audio chatroom Spaces is now open to anyone who wants to host.

Micro-blogging site Twitter has announced that its audio chatroom Spaces is now open to anyone who wants to host. The Spaces team in a tweet said that the users on both Android and iOS will now be able to host Spaces. "The time has arrived -- we're now rolling out the ability for everyone on iOS and Android to host a Space," the firm said in a tweet.

Earlier this year, the company had limited access to hosting Spaces to accounts with at least 600 followers, saying that it found these accounts would be more likely to have a good experience due to the existing audience. Twitter recently announced a new accelerator programme for creators on its audio conversation platform Spaces, to "discover and reward" around 150 creators with technical, financial and marketing support.

The 'Twitter Spaces Spark' programme is a three-month accelerator initiative. Those selected will get a stipend of $2,500 per month, $500 in monthly ad credits to spend promoting their Spaces on Twitter and early access to new Twitter features. They will also get support from Twitter's official social media handles, and "opportunities for prioritised in-app discoverability for well-performing Spaces".

Twitter has also announced plans to roll out paid Ticketed Spaces for iOS users where some hosts on its live audio feature can now sell access to Ticketed Spaces. Twitter had previously said that it will take a 3 per cent cut of creators' earnings from Ticketed Spaces. (IANS/ MBI)


Keep reading... Show less