Friday, August 14, 2020
Home Life Style Health & Fitness 'Successful' Treatment: Man Free Of The AIDS Virus After A Stem Cell...

‘Successful’ Treatment: Man Free Of The AIDS Virus After A Stem Cell Ttransplant

Stem cell transplants typically are harsh procedures which start with radiation or chemotherapy to damage the body's existing immune system and make room for a new one.

A London man appears to be free of the AIDS virus after a stem cell transplant, the second success including the “Berlin patient,” doctors reported.

The therapy had an early success with Timothy Ray Brown, a U.S. man treated in Germany who is 12 years post-transplant and still free of HIV. Until now, Brown is the only person thought to have been cured of infection with HIV, the virus that causes AIDS.

 

The latest case “shows the cure of Timothy Brown was not a fluke and can be recreated,” said Dr. Keith Jerome of Fred Hutchinson Cancer Research Center in Seattle who had no role. He added that it could lead to a simpler approach that could be used more widely.

The case was published online Monday by the journal Nature and will be presented at an HIV conference in Seattle.

The patient has not been identified. He was diagnosed with HIV in 2003 and started taking drugs to control the infection in 2012. It’s unclear why he waited that long. He developed Hodgkin lymphoma that year and agreed to a stem cell transplant to treat the cancer in 2016.

AIDS
Usually, HIV patients expect to stay on daily pills for life to suppress the virus. When drugs are stopped, the virus roars back, usually in two to three weeks. VOA

With the right kind of donor, his doctors figured, the London patient might get a bonus beyond treating his cancer: a possible HIV cure.

Doctors found a donor with a gene mutation that confers natural resistance to HIV. About 1 percent of people descended from northern Europeans have inherited the mutation from both parents and are immune to most HIV. The donor had this double copy of the mutation.

That was “an improbable event,” said lead researcher Ravindra Gupta of University College London. “That’s why this has not been observed more frequently.”

The transplant changed the London patient’s immune system, giving him the donor’s mutation and HIV resistance.
The patient voluntarily stopped taking HIV drugs to see if the virus would come back.

Usually, HIV patients expect to stay on daily pills for life to suppress the virus. When drugs are stopped, the virus roars back, usually in two to three weeks.

Drugs
The patient has not been identified. He was diagnosed with HIV in 2003 and started taking drugs to control the infection in 2012. VOA

That didn’t happen with the London patient. There is still no trace of the virus after 18 months off the drugs.

Brown said he would like to meet the London patient and would encourage him to go public because “it’s been very useful for science and for giving hope to HIV-positive people, to people living with HIV,” he told The Associated Press Monday.

Stem cell transplants typically are harsh procedures which start with radiation or chemotherapy to damage the body’s existing immune system and make room for a new one. There are complications too. Brown had to have a second stem cell transplant when his leukemia returned.

Also Read: Air-polluted Cities On Increase In Asia, Coal Addiction Puts Chokehold

Compared to Brown, the London patient had a less punishing form of chemotherapy to get ready for the transplant, didn’t have radiation and had only a mild reaction to the transplant.

Dr. Gero Hutter, the German doctor who treated Brown, called the new case “great news” and “one piece in the HIV cure puzzle.” (VOA)

STAY CONNECTED

18,956FansLike
362FollowersFollow
1,779FollowersFollow

Most Popular

Ayushmann is One of the Most Earnest Actors of our Generation, Says Vaani Kapoor

Actress Vaani Kapoor looks forward to working with Ayushmann Khurrana in an upcoming film. She says Ayushmann is one of the most earnest actors...

TV Stars are Looked Down Upon, I Don’t Know Why: Hina Khan

She did television for over a decade and has featured in Hindi films, but actress Hina Khan fails to understand why small screen stars...

Vidya Balan Does Not Like to Follow Norms

By Sugandha Rawal Vidya Balan does not like to follow norms. She finds it easier to follow her heart. The actress says doing something that...

Here are Some Home Gardening Tips For You

By Puja Gupta Growing and maintaining a garden at home is a fun and rewarding way to care for nature. Especially in these boredom-filled days...

Enjoy Independence Day Weekend With Domestic Travel

The fact that we are now free to move outside our homes after months in lockdown and travel, is the sweetest feeling of independence...

Everything You Need to Know About Post-Weaning Depression

By Puja Gupta Post-weaning depression is a form of mental illness which can occur after a woman stops breastfeeding. Like other depression, it requires immediate...

Car Not Turning On? Three Main Areas to Look Into

You are heading to somewhere important. You get in the car, turn the ignition, but the engine doesn’t crank. Your heart sinks because not...

Benefits Of Buying An Online Term Plan 

Choosing the best savings-investment plan can secure your future financially. A life insurance plan is one of the best ways that you can provide...

Recent Comments