Sunday August 25, 2019

700 Percent rise in Antibiotic resistant Infections caused by bacteria in US Children

More than 75 percent of the antibiotic-resistant infections were already present when the young people were admitted to the hospital

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Bacteria, Wikimedia

New York, Feb 25, 2017:  Researchers have found a 700-per cent surge in infections caused by bacteria that is resistant to multiple kinds of antibiotics among children in the US.
According to researchers, these antibiotic resistant infections — caused by Enterobacteriaceae, a family of bacteria that also include such pathogens as Salmonella and Escherichia coli — are linked to longer hospital stays and potentially greater risk of death.

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The findings showed that the proportion of these infections in children caused by bacteria increased from 0.2 per cent in 2007 to 1.5 per cent in 2015, a more than 700 per cent increase in prevalence over the eight-year period.

“There is a clear and alarming upswing throughout US of antibiotic resistant Enterobacteriaceae infections in kids and teenagers,” said lead author Sharon B. Meropol, a pediatrician and epidemiologist at Case Western Reserve University in the US.

Bacterial infections resistant to multiple drugs are especially concerning in children, for whom there are a limited number of stronger antibiotics currently approved for use compared to adults, putting kids at higher risk for worse outcomes, the researchers said.

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For the study, published in the Journal of the Pediatric Infectious Diseases Society, the team analysed data from 48 children’s hospitals throughout the US, focusing on approximately 94,000 patients under the age of 18 who were diagnosed with Enterobacteriaceae – associated infections between 2007 and 2015.

More than 75 percent of the antibiotic-resistant infections were already present when the young people were admitted to the hospital, upending previous findings that the infections were mostly picked up in the hospital.

 This suggested that the bacteria may be increasingly spreading in the community.
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In addition, the bacterial infection may also cause a greater mortality risk among pediatric patients.

 “Health care providers have to make sure we only prescribe antibiotics when they’re really needed. It’s also essential to stop using antibiotics in healthy agricultural animals”, Meropol added. (IANS)

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Researchers Develop Way to Fight against Bacterial Infections using Electricity

Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device is placed in the body

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bacterial infections
Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device is placed in the body. Pixabay

Amid growing antibiotic resistance, Indian-origin researchers have developed a way to charge up the fight against bacterial infections using electricity.

The electric field-based dressing can not only disrupt biofilm infection, it can also prevent such infections from forming in the future, said the study published in the journal Annals of Surgery.

Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device is placed in the body.

bacterial infections
Amid growing antibiotic resistance, Indian-origin researchers have developed a way to charge up the fight against bacterial infections using electricity. Pixabay

These bacteria generate their own electricity, using their own electric fields to communicate and form the biofilm, which makes them more hostile and difficult to treat.

The dressing electrochemically self-generates 1 volt of electricity upon contact with body fluids such as wound fluid or blood, which is not enough to hurt or electrocute the patient, said the study.

Work conducted at the Indiana University School of Medicine by Chandan Sen and and Sashwati Roy led to the development of the dressing, Indiana University said in a statement on Friday.

bacterial infections
Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device is placed in the body. Pixabay

They discovered the dressing is not only successful in fighting the bacteria on its own, but when combined with other medications can make them even more effective.

The researchers believe that the discovery has the potential to create significant changes in the way physicians treat patients with bacterial infections which are resistant to antibiotics.

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“This shows for the first time that bacterial biofilm can be disrupted by using an electroceutical dressing,” said Chandan Sen, Director of the Indiana Center for Regenerative Medicine and Engineering.

“This has implications across surgery as biofilm presence can lead to many complications in successful surgical outcomes,” Sen added. (IANS)