Saturday January 19, 2019

Additives in E-Cigarettes Impair Lung Functioning

However, respiratory mechanics were adversely affected only in mice exposed to cigarette smoke and not to e-cigarette vapour after prolonged treatment

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e-cigarette
E-cigarette additives impair lung function: Study.

Flavouring and additive ingredients used in e-cigarettes are more likely to increase inflammation and impair lung function, according to new research.

E-cigarettes — popular battery-powered devices that simulate the act of smoking a traditional cigarette — dispense a vapour derived from liquid chemicals in a refillable cartridge.

Researchers from the University of Athens found that short-term exposure to e-cigarettes was enough to cause lung inflammation similar or worse than that seen in traditional cigarette use.

The study, published in the American Journal of Physiology – Lung Cellular and Molecular Physiology, examined several groups of mice that received whole-body exposure to varying chemical combinations four times each day.

Each exposure session was separated by 30-minute smoke-free intervals.

One group was exposed to cigarette smoke, another with e-cigarette vapour containing propylene glycol and vegetable glycerol — an odourless liquid derived from plant oils, the third with e-cigarette vapour containing propylene glycol and nicotine and another group was exposed to e-cigarette vapour containing propylene glycol, nicotine and tobacco flavouring.

e-cigarettes
In this April 11, 2018, photo, an unidentified 15-year-old high school student uses a vaping device near the school’s campus in Cambridge, Mass. Health and education officials across the country are raising alarms over wide underage use of e-cigarettes and other vaping products. The devices heat liquid into an inhalable vapor that’s sold in sugary flavors like mango and mint — and often with the addictive drug nicotine. VOA

The findings suggested an increase in markers of inflammation, mucus production and altered lung function in the propylene, propylene plus nicotine and flavouring groups after three days.

In addition, two inflammation-producing proteins became elevated only in the flavouring group, which suggested that some flavouring components on the market may not be safe for even short-term use.

The level of oxidative stress — stress at a cellular level — in the flavouring group was equal to or higher than that of the cigarette group.

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However, respiratory mechanics were adversely affected only in mice exposed to cigarette smoke and not to e-cigarette vapour after prolonged treatment.

“The observed detrimental effects in the lung upon (e-cigarette) vapour exposure in animal models highlight the need for further investigation of safety and toxicity of these rapidly expanding devices worldwide,” the researchers warned. (IANS)

Next Story

Drug Use Among Teens Down in The U.S. But Vaping Still On The Rise

The vaping explosion is a big worry, however. Health officials say nicotine is harmful to developing brains.

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e-cigarette, vaping
In this April 11, 2018, photo, an unidentified 15-year-old high school student uses a vaping device near the school's campus in Cambridge, Mass. Health and education officials across the country are raising alarms over wide underage use of e-cigarettes and other vaping products. The devices heat liquid into an inhalable vapor that's sold in sugary flavors like mango and mint — and often with the addictive drug nicotine. VOA

Twice as many high school students used nicotine-tinged electronic cigarettes this year compared with last year, an unprecedented jump in a large annual survey of teen smoking, drinking and drug use.

It was the largest single-year increase in the survey’s 44-year history, far surpassing a mid-1970s surge in marijuana smoking.

The findings, released Monday, echo those of a government survey earlier this year. That survey also found a dramatic rise in vaping among children and prompted federal regulators to press for measures that make it harder for kids to get them.

Experts attribute the jump to newer versions of e-cigarettes, like those by Juul Labs Inc. that resemble computer flash drives and can be used discreetly.

e-cigarette, cigarettes
Customers puff on e-cigarettes at the Henley Vaporium in New York City. VOA

Trina Hale, a junior at South Charleston High School in West Virginia, said vaping — specifically Juul — exploded at her school this year.

“They can put it in their sleeve or their pocket. They can do it wherever, whenever. They can do it in class if they’re sneaky about it,” she said.

Olivia Turman, a freshman at Cabell Midland High School in Ona, West Virginia, said she too has seen kids “hit their vape in class.”

The federally funded survey released Monday is conducted by University of Michigan researchers and has been operating since 1975. This year’s findings are based on responses from about 45,000 students in grades 8, 10 and 12 in schools across the country. It found 1 in 5 high school seniors reported having vaped nicotine in the previous month.

After vaping and alcohol, the most common thing teens use is marijuana, the survey found. About 1 in 4 students said they’d used marijuana at least once in the past year. It was more common in older kids — about 1 in 17 high school seniors said they use marijuana every day.

Vaping, teeth,e-cigarette, cigarettes
Nicotine vaping on rise among US teenagers: Survey. Pixabay

Overall, marijuana smoking is about the same level as it was the past few years. Vaping of marijuana rose, however.

More teens, however, are saying no to lots of other substances. Usage of alcohol, cigarettes, cocaine, LSD, ecstasy, heroin and opioid pills all declined.

Experts say it’s not clear what’s behind those trends, especially since the nation is in the midst of the deadliest drug overdose epidemic ever.

“What is it that we’re doing right with teenagers that we’re not doing with adults?” said Dr. Nora Volkow, director of the National Institute on Drug Abuse, a federal agency that funds the Michigan study.

One leading theory is that kids today are staying home and communicating on smartphones rather than hanging out and smoking, drinking or trying drugs.

Vaping, teeth,e-cigarette, cigarettes
In this Feb. 20, 2014 file photo, a customer exhales vapor from an e-cigarette at a store in New York. A growing number of e-cigarette and vaporizer sellers have started offering college scholarships as a way to get their brands listed on university websites. VOA

“Drug experimentation is a group activity,” Volkow said.

What about vaping? “Vaping mostly is an individual activity,” said David Jernigan, a Boston University researcher who tracks alcohol use.

The vaping explosion is a big worry, however. Health officials say nicotine is harmful to developing brains. Some researchers also believe vaping will make kids more likely to take up cigarettes, and perhaps later try other drugs.

Also Read: New Survey Shows Rise of Nicotine Vaping Among US Teenagers

So far that hasn’t happened, surveys show. But the Juul phenomenon is recent, noted Richard Miech, who oversees the Michigan survey.

If vaping does lead to cigarette use among teens, that may start to show up in the survey as early as next year, he added. (VOA)