Wednesday September 19, 2018

Alcohol-related liver cancer may have worse prognosis

Patients with alcohol-related liver cancer do not live as long as patients with liver cancer that is not associated with alcohol consumption, a new study suggests

0
//
33
protein
Cancer can be caused by excessive intake of sugar and carbohydrates too. Pixabay
Republish
Reprint
  • Patients with alcohol-related cancer cannot live long
  • They live shorter than people with non-alcoholic liver cancer
  • Efforts should be made during screening  and treatment to reduce the harm

Patients with alcohol-related liver cancer do not live as long as patients with liver cancer that is not associated with alcohol consumption, a new study suggests.

The findings suggest that patients with alcohol-related liver cancer have a reduced overall survival time mainly due to worse liver function and tumour characteristics at diagnosis. Liver cancer is the second leading cause of cancer-related deaths worldwide, with hepatitis B and C infections being the main causes.

Alcohol-related cancer patients survive less.

“To improve prognosis of liver cancer in the alcoholic population, efforts should be made to implement effective screening programmes for both cirrhosis and liver cancer, and to improve access to alcoholism treatment services,” said co-author Charlotte Costentin from the Hôpital Henri-Mondor in France.

To compare aspects of alcohol-related and non-alcohol-related liver cancer for the study, published in the journal Cancer, researchers examined 894 patients with newly diagnosed liver cancer who were followed for five years. As many as 582 patients had a history of chronic alcohol abuse and 312 did not. They also recorded whether patients with alcohol-related liver cancer were abstinent or not at the time of cancer diagnosis.

Also Read: Limit Alcohol Intake to cut Risk of Cancer, Say Experts

A total of 601 patients had died by the time of the investigator’s final analyses. Alcohol-related liver cancers were more likely to be diffuse and were detected in patients with worse liver function. Median overall survival was 9.7 versus 5.7 months in the non-alcohol-related and alcohol-related groups respectively.

When researchers looked at each stage of cancer individually, however, survival was similar in patients with non-alcohol related and alcohol related cancer. The findings indicate that efforts should be made to improve both screening for early signs of liver cancer and the management of alcohol abuse, the researcher said. IANS

Click here for reuse options!
Copyright 2018 NewsGram

Next Story

Gut Microbiota Can Help Identify Liver Cancer: Researchers

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

0
Liver Cancer
How gut microbiota can aid in early diagnosis of liver cancer.

Chinese researchers have identified gut microbiota as a new biomarker of liver cancer, that can help in early diagnosis as well as treatment of the condition.

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the third leading cause of cancer-related death worldwide.

Due to the absence of specific symptoms in early stages and the lack of diagnostic markers, most patients with HCC are often diagnosed in an advanced stage.

Liver Cancer
AFP is a plasma protein that is produced in abundance by the liver cells. Pixabay

Researchers from China’s Zhejiang University, and Zhengzhou University, found that the microbial diversity in patients with cirrhosis was significantly lower than that in healthy people, but it increased when cirrhosis develops into cancer, the Xinhua reported.

Human gut microbiota has been considered the most important micro-ecosystem living with the body, containing tens of trillions of microorganisms, including at least 1,000 species of bacteria with more than 3 million genes.

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

Liver Cancer
A high-magnification image from a 2012 glioblastoma case is seen as an example in this College of American Pathologists image released from Northfield. VOA

For the study, appearing in the journal Gut, the team collected 486 fecal samples from across the country.

Also Read: Deaths Due to Cancer Increases to More Than 18 Mn Every Year: WHO

About 12 bacteria genera decreased and six increased in patients with early cancer compared with healthy people.

According to researchers, more data and further studies are needed to confirm the validity and reliability of the model. (IANS)