Friday September 21, 2018

Bacteria in The Gut May Lead to Anxiety, Depression

The researchers are now working to identify specific populations of bacteria involved in these processes and the molecules that the bacteria produce

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Probiotics Not Effective in Reducing Anxiety: Study
Probiotics Not Effective in Reducing Anxiety: Study. Pixabay
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Gut bacteria plays a key role in infusing negative feelings in the brains of obese people, causing depression and anxiety, researchers say.

The findings showed that mice on a high-fat diet showed significantly more signs of anxiety, depression and obsessive behaviour than animals on standard diets.

In mice with high-fat diets, two areas of the brain, the hypothalamus, which helps to control whole body metabolism, and the nucleus accumbens, important in mood and behaviour, becomes insulin resistant.

“Your diet isn’t always necessarily just making your blood sugar higher or lower; it’s also changing a lot of signals coming from gut microbes and these signals make it all the way to the brain,” said C. Ronald Kahn, from the Joslin Diabetes Centre in the US.

“But all of these behaviours are reversed or improved when antibiotics that will change the gut microbiome were given with the high fat diet,” Kahn added.

Gut Bacteria.
Gut Bacteria. Pixabay

In the study, published in the journal Molecular Psychiatry, the team identified the effect of the microbiome by transferring gut bacteria from experimental mice to germ-free mice which did not have any bacteria of their own.

The animals which received bacteria from mice on a high-fat diet began to show increased levels of activity associated with anxiety and obsessive behaviour.

However, those who got microbes from mice on a high-fat diet plus antibiotics did not, even though they did not receive the antibiotics themselves.

Also Read: Depression, Anxiety May Lead to Teeth Loss

The researchers are now working to identify specific populations of bacteria involved in these processes and the molecules that the bacteria produce.

“If we could modify those bacteria, either by putting in more beneficial bacteria or reducing the number of harmful bacteria, that might be a way to see improved behaviour,” Kahn noted. (IANS)

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Depression in Children Stay Undetected by Parents and Teachers- Study

The gold standard for identifying children who might be at risk for developing depression later in life is to ask the children themselves

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Depression
Depression in children under-recognised by parents, teachers: Study. Pixabay

Parents and teachers may find it difficult to detect depression in young children, that can affect their social skills and academics, a new study shows.

According to Anxiety and Depression Association of America, as many as 2-3 per cent of children aged between 6-12 might have a major depressive disorder.

But parents and teachers face difficulties in recognising depression in children.

The findings, appearing in the Journal of School Psychology, showed that children who show mild to severe symptoms of depression in second and third grades are six times more likely to have skill deficits, such as difficulties with social skills or academics, than children without symptoms.

However, when teachers and parents were asked to rate a child’s level of depression, there was only about 5-10 per cent overlap in their ratings.

Depression
Parents and teachers face difficulties in recognising depression in children. Pixabay

“Some people would view that overlap as the truth about a child’s well-being and areas of disagreement as errors, but we need to explore the possibility that each of them are seeing different aspects of children’s behaviour and mental health,” said Keith Herman, professor in the University of Missouri (MU), College of Education.

For the study, the team completed profile analyses of 643 children in early elementary school to explore how patterns between student, teacher and parent reporting can be used to gain a holistic picture of a child’s mental health.

Herman suggested that mental health professionals could work with teachers and parents to identify depressive symptoms early by including self reports from children in mental health evaluations.

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“The gold standard for identifying children who might be at risk for developing depression later in life is to ask the children themselves,” noted Herman.

“However, even if a child doesn’t say they feel depressed, certain outward behaviours might provide clues to the state of the child’s mental health. It’s important for teachers and parents to catch these behaviours early to prevent long-term problems that occur with depression,” he said. (IANS)