Sunday July 21, 2019

Cautious! If You Smoke During Pregnancy Your Child Is At Grater Risk Of Being Obese

The current and future results could provide a springboard for the development of effective treatments against pediatric and adult obesity in babies born to smokers as well as those exposed to other in utero environmental exposures, the team noted.

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The new results suggest that smoking in pregnancy could lead to changes in the regulation of the genes that play an important role in fat cell development and, by extension, obesity. Pixabay

Children whose mothers smoked during their pregnancy are at increased risk of being obese later in life, say researchers.

The findings, published in the journal Experimental Physiology, showed that chemerin, a protein that is produced by fat cells and appears to play a role in energy storage, was more prevalent in the skin and isolated cells of infants whose mothers smoked during pregnancy.

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For the study, the researchers recruited a total of 65 new mothers. All of the infants were full-term and approximately half of all new mothers reported smoking during their pregnancies. Pixabay

Previous research had shown that chemerin is present in higher levels in the blood of obese people.

The new results suggest that smoking in pregnancy could lead to changes in the regulation of the genes that play an important role in fat cell development and, by extension, obesity.

smoking
“Our work demonstrated that expectant mothers who smoke cigarettes during pregnancy induce distinct changes in chemerin gene expression in their offspring,” Pearson said. Pixabay

“It has been consistently shown that mothers who smoke during pregnancy confer increased risk of obesity to their baby, but the mechanisms responsible for this increased risk are not well understood,” said Kevin Pearson from the University of Kentucky in the US.

“Our work demonstrated that expectant mothers who smoke cigarettes during pregnancy induce distinct changes in chemerin gene expression in their offspring,” Pearson said.

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For the study, the researchers recruited a total of 65 new mothers. All of the infants were full-term and approximately half of all new mothers reported smoking during their pregnancies.

The current and future results could provide a springboard for the development of effective treatments against pediatric and adult obesity in babies born to smokers as well as those exposed to other in utero environmental exposures, the team noted. (IANS)

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Consuming High- Fibre Diet may Reduce Risk of Preeclampsia During Pregnancy

Pregnancy outcomes and infant immunity are linked to gut bacteria

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The mother's gut bacteria and diet appear to be crucial to promoting healthy pregnancy. Pixabay

Ladies, please take note. Consuming a high-fibre diet may reduce the risk of preeclampsia during pregnancy, researchers have found.

“Simple recommendation to ‘eat real food, mostly plants and not too much’ might be the most effective primary prevention strategy for some of the most serious conditions of our time.

“The mother’s gut bacteria and diet appear to be crucial to promoting healthy pregnancy,” said study lead author Ralph Nanan, Professor at the University of Sydney.

The study, published in the journal Nature Communications, showed that pregnancy outcomes and infant immunity are linked to gut bacteria.

Fibre, Diet, Pregnancy
Ladies, please take note. Pixabay

Plant-based fibre is broken down in the gut by bacteria into factors that influence the immune system. The research team investigated the role of these metabolic products of gut bacteria during pregnancy.

The researchers found that in humans, reduced levels of acetate, which is mainly produced by fibre fermentation in the gut, is associated with the common and serious pregnancy-related condition preeclampsia.

Preeclampsia occurs in up to 10 per cent of pregnancies and is characterized by high blood pressure, protein in the urine and severe swelling in the mother’s body.

It also interferes with the child’s immune development whilst in the womb, with some evidence suggesting a link to higher rates of allergies and autoimmune diseases later in life.

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The study found that preeclampsia affected the development of an important foetal immune organ – the thymus – which sits just behind the breastbone.

Foetuses in preeclamptic pregnancies were found to have a much smaller thymus than children from healthy pregnancies.

The cells the thymus normally generates — called ‘T’ cells, and specifically those associated with the prevention of allergies and autoimmune conditions such as diabetes — also remained lower in infants after preeclampsia, even four years after delivery.

Fiber, Diet, Pregnancy
Consuming a high-fibre diet may reduce the risk of preeclampsia during pregnancy, researchers have found. Pixabay

The mechanisms of acetate on the developing foetal immune system were further examined in separate experiments involving mice that showed acetate was central in driving foetal thymus and ‘T’ cell development.

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The results showed that promoting specific metabolic products of gut bacteria during pregnancy might be an effective way to maintain a healthy pregnancy and to prevent allergies and autoimmune conditions later in life. (IANS)