Friday January 19, 2018

Childhood Passive Smoking May Up Arthritis Risk Later

Rheumatoid arthritis is a chronic inflammatory disorder affecting many joints

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Passive Smoking Dangers
Passive smoking in childhood has increased the risk of arthritis in adult smokers. Pixabay
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  • In smokers who had childhood passive exposure to smoke, the hazard ratio was 1.73 compared with non-smokers not exposed during childhood
  • The results of the study was presented at the Annual European Congress of Rheumatology (EULAR) 2017
  • Smoking led to the formation of new bony growths (known as syndesmophytes)

June 18, 2017: Exposure to passive smoking in childhood significantly increased the risk of developing rheumatoid arthritis in adult smokers, a study has showed.

Rheumatoid arthritis is a chronic inflammatory disorder affecting many joints, including those in the hands and feet.

The findings showed that in smokers who had childhood passive exposure to smoke, the hazard ratio was 1.73 compared with non-smokers not exposed during childhood.
“Our study highlights the importance of avoiding any tobacco environment in children, especially in those with a family history of rheumatoid arthritis,” said lead author Raphaele Seror, professor at the University Hospitals of South Paris, France.
The results of the study was presented at the Annual European Congress of Rheumatology (EULAR) 2017.
 Further, in a separate analysis smoking was also associated with increased progression of structural damage to the spine in patients with ankylosing spondylitis — a painful, progressive and disabling form of arthritis caused by chronic inflammation affecting the spine and large joints.
Smoking led to the formation of new bony growths (known as syndesmophytes), the researchers said.
“Smoking constitutes a major risk factor not only for disease susceptibility but also disease severity in patients with AS,” said Servet Akar, professor from Izmir Katip Celebi University, Turkey.
“Rheumatologists should work hard to encourage their AS patients to quit smoking as this could have a major impact on future quality of life,” he added. (IANS)
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  • The exact cause of Rheumatoid Arthritis is not yet clear still. However, RA is considered to be caused by a genetic vulnerability triggered by environmental factors.

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Do you regularly take opioids and anti-depressants? This study says it may increase bone diseases

The researchers evaluated 11,049 rheumatoid arthritis patients, aged 40 and above, with no signs of osteoporotic fractures prior to the tests. After a median follow-up time of 5.7 years, the study found 863 patients affected with osteoporotic fractures.

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Anti-depressants may increase the risk of developing bone fractures, says a new study

New York, November 6, 2017 : Consuming opioids and anti-depressants may increase the risk of developing bone fractures among people who are already suffering from rheumatoid arthritis, says a new study.

Rheumatoid arthritis is a chronic disease that causes pain, stiffness, swelling, and limitation in the motion and function of multiple joints and organs of the body.

Chronic inflammation and pain in arthritis patients further leads to several diseases like cardiovascular, mental and gastrointestinal disorders. People take multiple medications in such cases that sometimes influences the risk of osteoporotic fractures or a disease caused due to reduced bone density, the researchers noted.

ALSO READ Importance of Magnesium in Human body, Strenghtens bones

“Even at younger ages, rheumatoid arthritis is associated with a two-fold increased risk of osteoporosis and fractures due to chronic inflammation and glucocorticoid use. More importantly, osteoporotic fractures significantly contribute to the disability, health-related costs and mortality with substantially higher complication in rheumatoid arthritis patients,” said Gulsen Ozen, researcher at the University of Nebraska Medical Centre.

The researchers evaluated 11,049 rheumatoid arthritis patients, aged 40 and above, with no signs of osteoporotic fractures prior to the tests. After a median follow-up time of 5.7 years, the study found 863 patients affected with osteoporotic fractures.

The patients who developed fractures were significantly older and had higher disease risk and bone fracture risk at the baseline than those patients who did not experience fractures.

The results presented at the ACR/ARHP annual meeting 2017 in San Diego mentioned that the osteoporotic fracture risk increased within 30 days when the patients were given opioids. The associated medications also led to falls in certain cases.

“Knowing the risks associated with the use of these medications can guide rheumatologists and other physicians in choosing the most appropriate management strategies in patients, particularly the ones who have a high fracture or fall risk,” Ozen added. (IANS)