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Chinese scientists develop Ebola vaccine; new drug found safe in early human trials

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By Newsgram Staff Writer

Scientist of the Beijing Institute of Biotechnology and the Tianjin Can Sino Biotechnology, have developed a new Ebola virus vaccine which will have lasting immunity. This vaccine has been found to be safe in the first phase, one trial based on the 2014 strain of the virus.

Until now, all tested Ebola virus vaccines have been based on the virus strain from the Zaire outbreak in 1976.

“On the basis of our findings, we believe that the Ebola vaccine we assessed has some potential,” said researcher Fengcai Zhu from the Jiangsu Provincial Center for Disease Prevention and Control in China.

“A significant advantage of this type of vaccine is that stable and much easier to store or transport in tropical areas with inadequate cold-chain capacity, such as Africa,” Zhu added.

For the trial, 120 healthy Chinese adults were randomly assigned in equal numbers to receive placebo, a low dose, or high dose of the vaccine.

The researchers found that 28 days after vaccination, 38 out of 40 participants in the low-dose group and all 40 of those in the high-dose group had a positive immune response to the vaccine, with participants in the high-dose group producing higher quantities of antibodies than those in the low-dose group.

However, the researchers are not sure if this vaccine will be the perfect vaccine to fight Ebola virus.
“Whether this candidate vaccine could become a final vaccine for widespread use against Ebola outbreaks is still uncertain, because of the issues of HIV-1 acquisition rates and the pre-existing immunity, especially in west Africa,” Zhu noted.

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