Sunday August 25, 2019

Combat obesity with your body’s built-in weighing scale

The system, which regulates weight gain by calculating body weight and fat mass, can help understanding the causes of obesity and ca facilitate new anti-obesity drugs.

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Obesity can now be cured by our body's natural weighing scales.
Obesity can now be cured by our body's natural weighing scales.
  • Human body’s natural weighing scales can now help cure obesity.
  • The study of these scales can help us understand the reasons and cures for obesity.

Human body consists of an internal body weight sensing system that operates like bathroom scales, registering body weight and signalling the brain to reduce food intake, researchers have found.

The system, which regulates weight gain by calculating body weight and fat mass, could lead to a better understanding of the causes of obesity as well as new anti-obesity drugs.

The results also explain why several studies have coupled sitting habit with obesity and bad health. It is because the “internal body scales give an inaccurately low measure when you sit down. As a result you eat more and gain weight,” the researchers said.

Sitting has been closely associated by the researchers, as a cause of obesity,
Sitting has been closely associated by the researchers, as a cause of obesity,

“We have found support for the existence of internal bathroom scales. The weight of the body is registered in the lower extremities. If the body weight tends to increase, a signal is sent to the brain to decrease food intake and keep the body weight constant,” said John-Olov Jansson, Professor at Sahlgrenska Academy, University of Gothenburg in Sweden.

Further, the results demonstrate that the weight sensing system regulates fat mass independently of leptin — a weight loss hormone. It is possible that leptin combined with activation of the internal body scales can become an effective treatment for obesity, the researchers said.

For the study, published in the journal Proceedings of the National Academy of Sciences (PNAS), the team performed experiments on obese rodents that were made artificially heavier by loading with extra weights.

The animals lost almost as much weight as the artificial load. The extra weights caused body fat to decrease and blood glucose levels to improve. IANS

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Whole Body Vibration (WBV) Significantly Improves How Well Our Body Uses Glucose as Energy

The researchers, using a mouse model, showed that WBV alters the microbiome, a collection of microorganisms in our body

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The study's findings, published in the International Journal of Molecular Sciences, showed how regular use of whole body vibration can create this healthier mix by yielding a greater percentage of macrophages. Pixabay

Whole body vibration (WBV) can significantly improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to reduce diabetic inflammation, says a new study.

The study’s findings, published in the International Journal of Molecular Sciences, showed how regular use of whole body vibration can create this healthier mix by yielding a greater percentage of macrophages — cells that can both promote or prevent inflammation — that suppress rather than promote.

The researchers, using a mouse model, showed that WBV alters the microbiome, a collection of microorganisms in our body, which help protect us from invaders and, in the gut, help us digest food.

They saw several changes including increased levels of a bacterium that makes short chain fatty acids, which can help the body better utilise glucose.

Body, Vibration, Glucose
Whole body vibration (WBV) can significantly improve how well our body uses glucose as an energy source and adjust our microbiome and immune cells to reduce diabetic inflammation. Pixabay

Glucose is used by the body for fuel but at high levels it promotes inflammation, insulin insensitivity and ultimately can cause diabetes.

“While there were other changes, the most dramatic they documented was the 17-fold increase in this bacterium called Alistipes, a gut bacterium not typically in high supply there but known to be proficient at making short chain fatty acids which, in turn, are “very good” at decreasing inflammation in the gut,” said Jack Yu, chief of pediatric plastic surgery at Medical College of Georgia, Augusta University.

Alistipes, which helps ferment our food without producing alcohol, generally improves the metabolic status of our gut and makes us more proficient at using the glucose we consume for energy.

The researchers reiterated that while no one is certain just how WBV works, but it appears to help address a key concern in diabetes and many common diseases: inflammation.

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While acute inflammation helps us fight disease, chronic inflammation helps start and sustain a variety of diseases from cardiovascular problems to cancer as well as diabetes, the researchers said. (IANS)