Friday October 19, 2018

Combination of Drugs for Diabetes and Hypertension may offer an effective new way to combat Cancer

the researchers found that the combination of the diabetes drug metformin and the antihypertensive drug syrosingopine drives cancer cells to programmed "suicide".

1
//
351
Suicide for cancer cells via a combination drug
A combination drug of diabeties and hypertension to cure cancer,pixabay
Republish
Reprint

London, December 28, 2016: A combination of drugs for diabetes and hypertension may offer an effective new way to combat cancer, suggests a new research.

In their experiments, the researchers found that the combination of the diabetes drug metformin and the antihypertensive drug syrosingopine drives cancer cells to programmed “suicide”.

NewsGram brings to you current foreign news from all over the world.

 “We have been able to show that the two known drugs lead to more profound effects on cancer cell proliferation than each drug alone,” said study first author Don Benjamin from the University of Basel in Switzerland.

“The data from this study support the development of combination approaches for the treatment of cancer patients,” Benjamin noted.

NewsGram brings to you top news around the world today.

Metformin is a widely prescribed drug for the treatment of Type-2 diabetes.

Besides its blood sugar lowering effect, it also displays anti-cancer properties. The usual therapeutic dose, however, is too low to effectively fight cancer.

At higher doses, the antidiabetic drug inhibits the growth of cancer cells but could also induce unwanted side effects.

The new research published in the journal Science Advances showed that the antihypertensive drug syrosingopine enhances the anti-cancer efficacy of metformin.

The study showed the cocktail of these two drugs is effective in a wide range of cancers.

“For example, in samples from leukemia patients, we demonstrated that almost all tumour cells were killed by this cocktail and at doses that are actually not toxic to normal cells”, Benjamin said.

Check out NewsGram for latest international news updates.

“And the effect was exclusively confined to cancer cells, as the blood cells from healthy donors were insensitive to the treatment,” Benjamin noted.

In mice with malignant liver cancer, enlargement of the liver was reduced after the therapy. Also the number of tumor nodules was less — in some animals the tumours disappeared completely.

The researchers found that the drugs interrupt the vital processes which provide energy for the cancer cell. (IANS)

Click here for reuse options!
Copyright 2017 NewsGram

  • Ruth

    I don’t like drink cocktail.

Next Story

Aishwarya Rai Bachchan Feels Need For More Awareness Among People Regarding Cancer

She applauded WCI's event for supporting and taking care of various issues related to cancer, especially amongst underprivileged women

0
Aishwarya Rai Bachchan.
Aishwarya Rai Bachchan.

Actress Aishwarya Rai Bachchan, who supported a Women’s Cancer Initiative (WCI) event here, says people generally need to be more aware about the disease as early detection can give them a better chance at a cure.

Aishwarya interacted with the media when she supported WCI’s Soul Stirrings event, hosted by Tata Memorial Hospital here on Tuesday.

The actress and former Miss World pointed out that there are many myths in the country about cancer as a disease.

“There are so many myths and misconceptions in our country that it is astonishing to realise and recognise that there are so many people even in this day and age who believe that a disease like cancer could possibly be contagious to us. That’s shocking, but to many it seems that’s a fact.

“That just boils down to lack of awareness, education, access to information, recognising what this disease is all about and the step you need to take as simple as early detection,” she said.

Aishwarya Rai hopes people get more aware around cancer
Aishwarya Rai hopes people get more aware around cancer. Pixabay

Aishwarya Rai Bachchan said it is important to educate people and create awareness among them about cancer.

“Events such as these have come together to draw attention and raise awareness, increase dialogue, make information more accessible to people and have people coming for their regular check-ups for early detection because that in the course of action is referred to as a baby step, but it is the most important step to a possible cure of the disease when a patient has it.

Also Read- ASUS Unveils 2 New Smartphones In India

“So, earlier detection gives you a higher chance at a cure and that’s a possibility that every person should humanly have a right to access. We hope this early detection of curable cancer in women will be an important component of the cancer control program in India.”

She applauded WCI’s event for supporting and taking care of various issues related to cancer, especially amongst underprivileged women. (IANS)