Tuesday April 23, 2019

Distress May Spike up Risk of Dementia

For the study, the team included 6,807 Danish participants aged 60 years on average

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Extreme distress increases risk for dementia: Study. Pixabay

Men and women who are distressed in midlife could be at higher risk of developing dementia in their old age, suggests a new study.

The study showed that vital exhaustion, which can be perceived as an indicator of psychological distress, is a risk factor for future risk of dementia.

Psychological distress is potentially linked to the risk of dementia through neurological and cardiovascular mechanisms.

The findings, led by researchers from the University of Copenhagen in Denmark, revealed that for each additional symptom of vital exhaustion, the risk of dementia rose by two per cent.

While participants reporting five to nine symptoms had a 25 per cent higher risk of dementia than those with no symptoms, those reporting 10 to 17 symptoms had a 40 per cent higher risk of dementia compared with not having symptoms.

However, the researchers are yet not aware of "exactly how anticholinergics might cause dementia", the researchers said.
Representational Image- dementia, Pixabay

Importantly, physiological stress response, including cardiovascular changes and excessive production of cortisol over a prolonged period, may also contribute to linking psychological distress with an increased risk of dementia, revealed the study published in the Journal of Alzheimer’s Disease.

“Stress can have severe and harmful consequences not just for our brain health, but our health in general. Cardiovascular risk factors are well-known modifiable risk factors for dementia, and in some countries, a stagnation or even a decreasing incidence of dementia has been observed,” said Sabrina Islamoska, postdoctoral student from the varsity.

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For the study, the team included 6,807 Danish participants aged 60 years on average.

Psychological distress is an important risk factor that should receive more focus when considering prevention initiatives in relation to later dementia, the team said. (IANS)

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Late Onset of Menstruation May Spike up Dementia Risk, Says Study

For the study, the researchers involved 6,137 women among which 42 per cent later developed dementia

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However, the researchers are yet not aware of
Representational Image- dementia, Pixabay

Women whose menstruation starts later and those who enter menopause early may have a greater risk of developing dementia, say researchers.

The findings showed that women who had their first menstrual cycle at age 16 or older had a 23 per cent greater risk of dementia than women who had their first menstrual cycle at age 13.

Women who went through natural menopause before age 47 had a 19 per cent greater risk of dementia than women who went through menopause at age 47 or older.

In addition, women who had hysterectomy — surgery to remove all or part of the uterus — had an eight per cent greater risk of dementia than those who did not, according to the study, published in the journal Neurology.

1 in 6 people over the age of 80 have dementia. Pixabay
1 in 6 people over the age of 80 have dementia. Pixabay

“Oestrogen levels can go up and down throughout a woman’s lifetime. Our results show that less exposure to oestrogen over the course of a lifetime is linked to an increased risk of dementia,” said Paola Gilsanz, Researcher at Kaiser Permanente – a US-based healthcare company.

For the study, the researchers involved 6,137 women among which 42 per cent later developed dementia.

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“Since women are 50 per cent more likely to develop dementia over their lifetimes than men, it’s important to study any risk factors that are specific to women that could eventually lead us to potential points of intervention,” Gilsanz suggested. (IANS)