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Donald Trump Presidency likely to spark “Brain Drain” as Foreign-born Researchers Educated in American Universities may leave Country

57.11 per cent, believe that the president-elect will hurt research funding of Health (NIH), a public biomedical research facility

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Representational image. Pixabay

New York, November 12, 2016: Adding to the anxiety that the US Presidential election results have caused, a large number of scientists in the country, according to a survey, now fear that a Donald Trump presidency might spark a “brain drain” as foreign-born researchers educated in American universities will be more likely to leave the country.

Thousands of people all across the US marched down the streets and inter-states opposing Republican Donald Trump’s victory in the presidential election, the media reports said.

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According to the survey of more than 1,600 professionals, from industry and academia, 46.78 per cent believe that during the reign of Trump scientists born in other countries but educated in the US will be more likely to make an exit.

On other hand, 49.81 per cent opined that overseas researchers will still seek academic positions or jobs in the US biotech industry, while 30.21 per cent said they were uncertain, and 19.97 per cent, disagreed.

“The biotechnology industry faces the possibility of a brain drain, and this is most alarming,” said Mary Ann Liebert, founder and CEO of the the journal Genetic Engineering And Biotechnology News (GEN).

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Further, 57.11 per cent, believe that the president-elect will hurt research funding of Health (NIH) — a public biomedical research facility. As much as 24.26 per cent said it would not make a difference, and 9.79 per cent said Trump’s presidency would prove positive.

While 51.74 per cent, believe that science-technology-engineering-mathematics (STEM) education will not be a priority under a Trump administration, 29.25 per cent are uncertain.

However, 19.01 per cent believe that a Trump administration will focus attention on STEM education, as during the campaign to the White House, Trump had hinted at possible support for higher NIH budgets, even as he has called for cutting federal spending.

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“We must make the commitment to invest in science, engineering, healthcare and other areas that will make the lives of Americans better, safer and more prosperous,” Trump had said.

Whether Trump will make measures that benefit biopharma industry, remains uncertain, the researchers noted in the journal Genetic Engineering And Biotechnolgy News. (IANS)

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Chinese Scientists Develop Combined Tumor-Killing Therapy

The Chinese Academy of Sciences and Fudan University developed a common immune checkpoint inhibitor in a nanoparticle formulation

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Chinese, Scientists, Tumor
The study published on Friday in the journal Science Immunology described the new cancer immunotherapy that can prevent the immune system from becoming tolerant of tumors. Pixabay

Chinese scientists developed a combined tumor-killing therapy that can be activated specifically at tumor sites in mouse models of cancer, which is more effective than previous similar therapies.

The study published on Friday in the journal Science Immunology described the new cancer immunotherapy that can prevent the immune system from becoming tolerant of tumors, which occurs in 30 per cent of all cancer patients, the Xinhua news agency reported.

A team led by Wang Dangge from Shanghai Institute of Materia Medica under the Chinese Academy of Sciences and Fudan University developed a common immune checkpoint inhibitor in a nanoparticle formulation, which is highly tumor-specific.

The checkpoint inhibitor is a kind of increasingly popular anti-tumor drug. It can block proteins that keep immune T cells from killing cancer. But the checkpoint inhibitor used to target those immune system-suppressing proteins like PD-1 and PD-L1 often fails to reach deep-seated or metastatic tumors.

Chinese, Scientists, Tumor
Chinese scientists developed a combined tumor-killing therapy that can be activated specifically at tumor sites in mouse models of cancer, Pixabay

Wang’s team combined the nanoparticles carrying PD-L1-targeting antibodies with a light-activated molecule. The molecule called photosensitiser can produce tumor-killing reactive oxygen species after encountering a protein abundant in tumors, according to the study.

In mouse models, a local near-infrared radiation that activated the photosensitiser, along with the administration of antibodies-carrying nanoparticles, promoted the infiltration of cancer cell-killing T cells into the tumor site and made the tumors more sensitive to the checkpoint blockade.

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This combination also helped the nanoparticles effectively suppress tumor growth and metastasis to the lung and lymph nodes, resulting in approximately 80 per cent mouse survival over 70 days, compared to complete mouse death in 45 days in the group treated with only PD-L1 antibodies, according to the study. (IANS)