Tuesday January 21, 2020

Eating almonds, peanuts may boost colon cancer survival

Patients may not be eating nuts due to concerns about the high-fat content and that increasing nut consumption will lead to obesity, which leads to worse outcomes says a study

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Almonds and other nuts can improve survival of patients suffering from colon cancer as well.
  • Eating peanuts and almonds can boost colon cancer survival
  • They also lower its occurrence
  • Patients should not worry about high fat-content

People with colon cancer who regularly eat nuts such as almonds, walnuts, hazelnuts, cashews and peanuts may be at significantly lower risk of cancer recurrence and mortality, researchers say.

Colon Cancer can be very dangerous. Pixabay

The findings showed that those who regularly consumed at least two, one-ounce servings of nuts each week showed a 42 percent improvement in disease-free survival and a 57 percent improvement in overall survival. In patients with stage III colon cancer, recurrence was reduced by nearly half.

“These findings are in keeping with several other observational studies that indicate that a slew of healthy behaviours, including increased physical activity, keeping a healthy weight, and lower intake of sugar and sweetened beverages, improve colon cancer outcomes,” said lead author Temidayo Fadelu, postdoctoral student at Dana-Farber Cancer Institute in Boston.

Also Read: New Combo Therapy Found Effective In Kidney Cancer Patients

“The results highlight the importance of emphasising dietary and lifestyle factors in colon cancer survivorship,” Fadelu added. The study, published in the Journal of Clinical Oncology, followed 826 participants in a clinical trial for a median of 6.5 years after they were treated with surgery and chemotherapy.

Almonds can help increase survival during the colon cancer.

Patients may not be eating nuts due to concerns about the high-fat content and that increasing nut consumption will lead to obesity, which leads to worse outcomes. On the contrary, “our studies, and across the scientific literature in general, have found regular consumers of nuts tend to be leaner”, explained Charles S. Fuchs, Director at Yale Cancer Centre in the US.

Also Read: Omega-3s from fish more effective in cancer prevention

Many previous studies have reported that nuts also help to reduce insulin resistance. “These studies support the hypothesis that behaviours that make you less insulin resistant, including eating nuts, seem to improve outcomes in colon cancer,” Fuchs said. Nuts also might play a positive role by satisfying hunger with less intake of carbohydrates or other foods associated with poor outcomes, Fuchs noted. IANS

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Males Have Higher Risk of Suffering from Cancer: Study

Researchers explain why cancer risk is higher in males

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Cancer
DNA differences between men and women may explain why cancer risk is higher in males. Pixabay

DNA differences between men and women may explain why cancer risk is higher in males, according to a new study.

In findings published in the Journal of the National Cancer Institute, researchers have reported that loss of function in certain genes of the sex-determining Y chromosome, which is present only in men, may cause them to have an elevated risk for cancer.

Using data from 9,000 individuals, the researchers studied Y-chromosome gene function in patients with various types of cancer. The findings showed that cancer risk increases with loss of function of six key Y-chromosome genes in various types of cells.

“Recent studies have shown that complete loss of the Y chromosome, which is essential to foetal sex differentiation, occurs, with aging, in the cells of some men,” said study author Juan Ramon Gonzalez from Barcelona Institute for Global Health in Spain.

Cancer DNA
Suppression of the Y chromosome can occur as a result of loss of function in the chromosome. Pixabay

“Although the loss of the Y chromosome has previously been associated with higher incidence of cancer, the causes of this association are poorly understood,” Gonzalez added.

These six Y-chromosome genes are involved in cell-cycle regulation, the failure of which can lead to tumour development.

According to the study, understanding the biological differences between men and women in cancer is crucial for the development of personalised lines of treatment and prevention.

“Men are not only at higher risk of cancer than women, they also face a worse prognosis. In fact, these differences partially account for the lower life expectancy of men,” Gonzalez added.

According to the researchers, although men may be more exposed to carcinogens due to the type of work they do and at higher risk because they are less likely to consult a doctor, the study has shown that there are also biological factors that increase cancer risk among men.

“In fact, it seems that one of these factors can be found in the Y chromosome, the very essence of maleness,” said study lead author Alejandro Caceres.

Also Read- Know About the Health Benefits of Green Tea

Suppression of the Y chromosome can occur as a result of loss of function in the chromosome, which would explain previous findings, or as a result of other mechanisms mediated by the chemical (epigenetic) inactivation of the same regions, the research said.

“Certain environmental exposures, for example to tobacco or other harmful substances, could affect chromosome function and lead to epigenetic modifications,” Gonzalez said. (IANS)