Tuesday December 11, 2018

Exercise may become anti-cancer therapy in future

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For the first time international clinical trial has been evaluating the effect of intense physical exercise on the body to improve survival of men with advanced prostate cancer is underway.

Physical exercise has a direct effect on cancer — as effective as drugs — for treating patients with prostate cancer even in advanced stages of the disease said Dr Fred Saad, urologist-oncologist and researcher at the University of Montreal Hospital Research Centre (CRCHUM)

“Typical patients with metastases often become sedentary. It is thought that this affects cancer progression,” he said.

Together with Robert Newton, professor at the Edith Cowan University Exercise Medicine Research Institute in Australia, Dr Saad is leading the first international study which aims to demonstrate that exercise literally extends the life of patients with metastatic prostate cancer.

Normally, patients at this stage have a life expectancy of two to three years.

“We want to reduce mortality by at least 22 percent, which represents about six months of longer survival. This is the equivalent benefit of a new drug. Exercise could therefore supplement available treatments, inexpensively,” said Dr Saad.

The study has already started in Ireland and Australia. In the coming weeks, some 60 hospitals across the world will begin recruiting patients. In total, nearly 900 men with advanced prostate cancer will participate.

“We will study exercise as if it were a drug added to standard treatments. All patients will be treated within the latest scientific knowledge for this type of cancer,” he explained.

The team has designed a specific strength and cardiovascular training programme for patients in the “exercise” group.They will have an hour of aerobic and resistance training three times a week.

An exercise specialist will supervise them for the first 12 months, and then they will continue without direct supervision. They will be evaluated for quality of life, appetite, and treatment tolerance in relation to their improved physical condition.

The Theory is that cancer progression is directly affected by exercise in addition it also helps patient tolerate therapy better

Overview of the Phase 3 clinical trial will be presented by Dr Saad at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago from June 3-7.

-by Bhaskar Raghavendran

Bhaskar is a graduate in Journalism and mass communication from Amity school of communication, Noida. Contact the author at Twitter: bhaskar_ragha

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  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

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  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

Next Story

Here’s How Exercise Can Help Breast Cancer Survivors

Among those who completed the program, those who received the lifestyle intervention were about 50 per cent more likely to have disease-free survival than those who received the general recommendations

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exercise
How exercise can help breast cancer survivors. Pixabay

Survivors of early-stage breast cancer who exercise and eat a healthy diet are more likely to lose weight and experience higher rates of disease-free survival, a new study suggests.

The research is based on an examination of a lifestyle intervention that included exercise, diet, and at least one other component such as counselling, stress management, and discontinuing tobacco smoking.

The study showed that obesity and low physical activity are associated with higher risks of developing breast cancer, as well as an increased risk of recurrence and reduced survival.

“Lifestyle intervention might improve the prognosis of breast cancer patients if adherence is high,” said Wolfgang Janni from the University of Ulm in Germany.

“Many breast cancer survivors would like to contribute actively to improving their prognosis, and guiding them on lifestyle factors that can help them control weight is one possible way to positively impact patient outcomes,” said Janni.

For the study, the researchers enrolled 2,292 women among which all had a body mass index of 24 or higher.

Cancer
Cancer Ribbon. Pixabay

Some women were randomly assigned to receive either telephone-based lifestyle intervention for two years while others received general recommendations for a healthy lifestyle alone.

Those who received the telephone calls were given advice on how to improve their diets, lower fat intake, increase physical activity, achieve moderate weight loss and other tips that were geared to their specific needs.

Findings, presented at the 2018 San Antonio Breast Cancer Symposium in the US, demonstrated that patients in the lifestyle intervention arm had lost an average of one kg, while the patients in the control group had gained an average of 0.95 kg.

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Overall, 1,477 patients completed the lifestyle intervention. Those who completed the program had a 35 per cent higher rate of disease-free survival than those who began the program but did not complete it.

Among those who completed the program, those who received the lifestyle intervention were about 50 per cent more likely to have disease-free survival than those who received the general recommendations. (IANS)