Monday July 23, 2018

Exercise may become anti-cancer therapy in future

2
//
176
Republish
Reprint

For the first time international clinical trial has been evaluating the effect of intense physical exercise on the body to improve survival of men with advanced prostate cancer is underway.

Physical exercise has a direct effect on cancer — as effective as drugs — for treating patients with prostate cancer even in advanced stages of the disease said Dr Fred Saad, urologist-oncologist and researcher at the University of Montreal Hospital Research Centre (CRCHUM)

“Typical patients with metastases often become sedentary. It is thought that this affects cancer progression,” he said.

Together with Robert Newton, professor at the Edith Cowan University Exercise Medicine Research Institute in Australia, Dr Saad is leading the first international study which aims to demonstrate that exercise literally extends the life of patients with metastatic prostate cancer.

Normally, patients at this stage have a life expectancy of two to three years.

“We want to reduce mortality by at least 22 percent, which represents about six months of longer survival. This is the equivalent benefit of a new drug. Exercise could therefore supplement available treatments, inexpensively,” said Dr Saad.

The study has already started in Ireland and Australia. In the coming weeks, some 60 hospitals across the world will begin recruiting patients. In total, nearly 900 men with advanced prostate cancer will participate.

“We will study exercise as if it were a drug added to standard treatments. All patients will be treated within the latest scientific knowledge for this type of cancer,” he explained.

The team has designed a specific strength and cardiovascular training programme for patients in the “exercise” group.They will have an hour of aerobic and resistance training three times a week.

An exercise specialist will supervise them for the first 12 months, and then they will continue without direct supervision. They will be evaluated for quality of life, appetite, and treatment tolerance in relation to their improved physical condition.

The Theory is that cancer progression is directly affected by exercise in addition it also helps patient tolerate therapy better

Overview of the Phase 3 clinical trial will be presented by Dr Saad at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago from June 3-7.

-by Bhaskar Raghavendran

Bhaskar is a graduate in Journalism and mass communication from Amity school of communication, Noida. Contact the author at Twitter: bhaskar_ragha

Related Article:

Click here for reuse options!
Copyright 2016 NewsGram

  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

SHARE
  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

Next Story

Why Exercise on Empty Stomach May be Better for Your Health

This is the first study to show that feeding prior to acute exercise affects post-exercise adipose tissue gene expression

0
exercise
The study analysed effects of eating versus fasting on gene expression in adipose (fat) tissue in response to exercise. Pixabay

If you have been wondering whether it is better to eat or fast before a workout, researchers now have an answer. A new study has found that exercise on empty stomach is better for your health in the long term.

The study analysed effects of eating versus fasting on gene expression in adipose (fat) tissue in response to exercise.

After eating, adipose tissue “is busy responding to the meal and a bout of exercise at this time will not stimulate the same (beneficial) changes in adipose tissue”, explained corresponding author of the study Dylan Thompson from University of Bath in Britain.

“This means that exercise in a fasted state might provoke more favourable changes in adipose tissue, and this could be beneficial for health in the long term,” Thompson added.

“We propose that feeding is likely to blunt long-term adipose tissue adaptation to regular exercise,” the researchers noted in the study published in the American Journal of Physiology — Endocrinology and Metabolism.

The study participants were a group of overweight males who walked for 60 minutes at 60 per cent maximum oxygen consumption on an empty stomach and, on another occasion, two hours after consuming a high-calorie carbohydrate-rich breakfast.

The research team took multiple blood samples after eating or fasting and after exercising.

exercise
Representational image. Pixabay

The researchers also collected fat tissue samples immediately before and one hour after walking.

Gene expression in the adipose tissue differed significantly in the two trials.

The expression of two genes, PDK4 and HSL, increased when the men fasted and exercised and decreased when they ate before exercising.

The rise in PDK4 likely indicates that stored fat was used to fuel metabolism during exercise instead of carbohydrates from the recent meal.

Also Read: Even Light Exercises Have Health Benefits

HSL typically increases when adipose tissue uses stored energy to support increased activity, such as during exercise, Thompson said.

These results reinforce the view that “adipose tissue often faces competing challenges,” Thompson wrote.

“This is the first study to show that feeding prior to acute exercise affects post-exercise adipose tissue gene expression,” the study said. (Bollywood Country)