Monday April 22, 2019

Exercise may become anti-cancer therapy in future

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For the first time international clinical trial has been evaluating the effect of intense physical exercise on the body to improve survival of men with advanced prostate cancer is underway.

Physical exercise has a direct effect on cancer — as effective as drugs — for treating patients with prostate cancer even in advanced stages of the disease said Dr Fred Saad, urologist-oncologist and researcher at the University of Montreal Hospital Research Centre (CRCHUM)

“Typical patients with metastases often become sedentary. It is thought that this affects cancer progression,” he said.

Together with Robert Newton, professor at the Edith Cowan University Exercise Medicine Research Institute in Australia, Dr Saad is leading the first international study which aims to demonstrate that exercise literally extends the life of patients with metastatic prostate cancer.

Normally, patients at this stage have a life expectancy of two to three years.

“We want to reduce mortality by at least 22 percent, which represents about six months of longer survival. This is the equivalent benefit of a new drug. Exercise could therefore supplement available treatments, inexpensively,” said Dr Saad.

The study has already started in Ireland and Australia. In the coming weeks, some 60 hospitals across the world will begin recruiting patients. In total, nearly 900 men with advanced prostate cancer will participate.

“We will study exercise as if it were a drug added to standard treatments. All patients will be treated within the latest scientific knowledge for this type of cancer,” he explained.

The team has designed a specific strength and cardiovascular training programme for patients in the “exercise” group.They will have an hour of aerobic and resistance training three times a week.

An exercise specialist will supervise them for the first 12 months, and then they will continue without direct supervision. They will be evaluated for quality of life, appetite, and treatment tolerance in relation to their improved physical condition.

The Theory is that cancer progression is directly affected by exercise in addition it also helps patient tolerate therapy better

Overview of the Phase 3 clinical trial will be presented by Dr Saad at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago from June 3-7.

-by Bhaskar Raghavendran

Bhaskar is a graduate in Journalism and mass communication from Amity school of communication, Noida. Contact the author at Twitter: bhaskar_ragha

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  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

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  • Pritam Go Green

    Many scientists have proved that the power of yoga and exercise is much more than that of medicines. So yes people should definitely be taught the benefits of doing a regular exercise, Since it can cure dangerous diseases such as Cancer etc.

  • Akanksha Sharma

    Exercise can improve your health and reduce the risk of developing several diseases like diabetes, cancer and several heart diseases.

Next Story

Avoid Smoking During Pregnancy To Prevent Premature Births

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known. 

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smoking
The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality. Pixabay

Expecting mothers, take note. As smoking during pregnancy is linked with negative health outcomes, a team of researchers has found that smoking cessation during pregnancy may reduce the risk of pre-term birth.

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy.

baby
If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation. Pixabay

“Of concern, though, given the substantial benefits of smoking cessation during pregnancy is that the proportion of pre-pregnancy smokers who quit smoking during pregnancy has remained essentially stagnant since 2011,” said lead author Samir Soneji from The Dartmouth Institute for Health Policy and Clinical Practice in the US.

For the study, the researchers conducted a cross-sectional study of more than 25 million pregnant women who gave birth to live neonates during a six-year period — measuring their smoking frequency three months prior to pregnancy and for each trimester during pregnancy.

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known.

But the good news is that the proportion of women who start their pregnancy as smokers has been declining in recent years, the researchers said.

smoking

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy. Pixabay

However, the study also found that only about 25 per cent of women who smoked prior to pregnancy were able to quit throughout their pregnancy, and approximately 50 per cent of women who smoked during their pregnancy did so with high frequency (more than 10 cigarettes per day).

The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality.

Also Read: How Netflix Binge-Watching Can Lead You The “Mean World Syndrome”

“Thankfully most premature babies end up doing well,” he said.

“But premature birth is strongly linked to infant mortality. If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation,” he added. (IANS)